A5101951263- Atrial Fibrillation Management and Outcomes
- Acute Ischemic Stroke Management
- Cardiac Arrhythmias and Treatments
- Stroke Rehabilitation and Recovery
- Blood Pressure and Hypertension Studies
- Cardiac electrophysiology and arrhythmias
- Venous Thromboembolism Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Heart Rate Variability and Autonomic Control
- Rheumatoid Arthritis Research and Therapies
- Cerebrovascular and Carotid Artery Diseases
- Immunotherapy and Immune Responses
- Reproductive Biology and Fertility
- Transgenic Plants and Applications
- Video Analysis and Summarization
- Advanced Steganography and Watermarking Techniques
- Advanced Computational Techniques and Applications
- Peptidase Inhibition and Analysis
- Osteoarthritis Treatment and Mechanisms
- Cardiac tumors and thrombi
- Nausea and vomiting management
- Fungal Infections and Studies
- Estrogen and related hormone effects
- Aortic Disease and Treatment Approaches
- vaccines and immunoinformatics approaches
Shanghai Jiao Tong University
2014-2023
National Institute of Allergy and Infectious Diseases
2023
National Institutes of Health
2023
XinHua Hospital
2020-2023
Xuzhou Medical College
2023
Second Hospital of Anhui Medical University
2020-2022
Anhui Medical University
2020-2022
Institute of Cardiology
2021
Creative Commons
2020
Zero to Three
2020
Atrial fibrillation(AF) has become a significant public health concern in China, with population aging and urbanization.Data screening was performed for 30,244,930 subjects medical insurance the Shanghai Municipal Health Commission database between 2015 2020. Patients diagnosed AF were identified further assessed treatment information clinical outcomes, as well sex differences impact of COVID-19 pandemic on managment.AF prevalence 0.88% Shanghai, which increased age reached 6.70% at 80 years...
Background and Purpose— Although stroke in the young middle aged accounts for 31% of all strokes China, disease burden is unknown. We aimed to determine secular trends incidence transition subtypes rural China over a 24-year period. Methods— In 1992, 14 920 residents were recruited participate Tianjin Brain Study. Stroke events deaths registered annually. assessed first-ever stroke, including intracerebral hemorrhage ischemic among adults 35 64 years during 1992 1999, 2000 2007, 2008 2015....
Collagen type IV α1 chain (COL4A1) is a collagen protein that acts as tumor-promoting factor in several types of cancer. However, the role and potential mechanisms involving COL4A1 oral squamous cell carcinoma (OSCC) remain unclear. Using reverse transcription-quantitative PCR western blotting, expression levels (nidogen-1) NID1 OSCC cells were assessed. Cell Counting Kit-8, EdU staining colony formation assays used to evaluate proliferation. migration invasion assessed using wound healing...
Limited information exists on the long-term consequences of stroke in China. We aimed to describe profile and determinants health-related quality life among 12-month survivors stroke.The ChinaQUEST (QUality Evaluation Stroke care Treatment) study was a prospective 62-hospital registry patients with acute (ischemic intracerebral hemorrhage). Health-related determined using 35-item quality-of-life questionnaire (QOL-35) designed specifically for use Chinese people. Proxy responses were used...
Recently, the impact of fine particulate matter pollution on cardiovascular system is drawing considerable concern worldwide. The association between ambient and cardiac arrhythmias not clear now. To study associations with incidence in outpatients. Data was collected from remote electrocardiogram (ECG) covering 282 community hospitals Shanghai June 24th, 2014 to 23rd, 2016. ECG performed for patients admitted above complaining chest discomfort or palpitation, regular check-ups. Air quality...
Stroke is a major health issue in China.We aimed to describe the management of patients admitted hospitals China with acute ischaemic stroke, and determine whether there were any differences by age gender.Using multicentre prospective hospital register across all eight economic (geographic) regions China, data on socioeconomic characteristics, medical history, clinical features, in-hospital investigations, management, outcomes collected consecutive stroke due cerebral ischaemia during...
Abstract Background Moyamoya disease (MMD) is a rare and complex cerebrovascular disorder characterized by the progressive narrowing of internal carotid arteries formation compensatory collateral vessels. The etiology MMD remains enigmatic, making diagnosis management challenging. MOYAOMICS project was initiated to investigate molecular underpinnings explore potential diagnostic therapeutic strategies. Methods employs multidisciplinary approach, integrating various omics technologies,...
Post-operative nausea and vomiting (PONV) is a major peri-operative complication. It has numerous adverse consequences that seriously affect the post-operative recovery of patients. The aim present study was to investigate efficacy intravenous lidocaine in improving PONV after laparoscopic gynaecological surgery. A total 40 patients were randomly assigned 2 groups: Group L (lidocaine group) C (control group). received throughout operation, while given saline infusion. Vital signs, time,...
With population aging, the prevalence of both cancer and atrial fibrillation (AF) have increased. However, there is scarce epidemiological data concerning comorbid state AF in low- middle-income countries, including China.We aimed to evaluate site-, sex-, age-specific profiles comorbidities Chinese populations.Data from Shanghai Municipal Health Commission database between 2015 2020 were screened, covering all medical records residents with insurance. Site-specific evaluated for relative...
Background Atrial fibrillation (AF) is the most common arrhythmia, and incidence increases rapidly all over world. The global prevalence of AF (age-adjusted) 0.60% for men 0.37% women in China 0.65%. It expected that number patients with will continue to rise future worldwide due population aging. Objective To explore Chinese community 2019 clarify complicated other arrhythmias myocardial ischemia (MI) events. Methods remote electrocardiogram (ECG) diagnosis system Xinhua Hospital was...
Cholecystokinin (CCK) and gastrin exert their influences via CCK receptors. This research was conducted to look at the responses of sling clasp fibers forming human lower esophageal sphincter (LES) gastrin, role receptors in responses.Muscle strips from LES were obtained patients undergoing subtotal esophagectomy. Isometric tension CCK-8 gastrin-17 studied, maximum effect (E(max)) for each agonist derived. CCK-A receptor antagonist, CR1409 CCK-B CR2945 applied pK(B) values calculated.Sling...
So far, a large number of transformation systems have been established for japonica rice, but only few reported cold-region varieties. In our study, we highly efficient tissue culture two rice cultivars, Dongnong 427 and Longdao 14. Plant growth regulator (PGR) levels were optimized by an orthogonal experimental design. The ability, constituted induction differentiation rate, served as the detection index experiments. optimal combinations PGRs callus regeneration 14 1 mg/l...
To enable rationale vaccine design, studies of molecular and cellular mechanisms immune recognition need to be linked with clinical in humans. A major challenge conducting such translational research lies the management integration large amounts various types data collected from multiple sources. For this purpose, we have established “IMMUNOCAT”, an interactive system for epitope discovery projects conducted by our group. The provides functions store, query, analyze experimental data,...
We describe, to our knowledge, the first case of limb-threatening necrotizing alternariosis whose limbs were successfully salvaged by adjunctive hyperbaric oxygen therapy (HBO2). This 58-y-old patient was immunocompromised with both diabetes and Cushing's syndrome. She suffered from soft tissue infection legs caused Alternaria. It impossible halt progression invasive standard anti-fungal treatment aggressive surgical debridement. After use HBO2, wound stabilized eventually healed. Adjunctive...
Background: Atrial fibrillation(AF) has become a significant public health concern in China, with population aging and urbanization.Methods: Data screening was performed for 30,244,930 Medicare subjects the Shanghai Municipal Health Commission database between 2015 2020. Patients diagnosed AF were identified further assessed treatment information clinical outcomes.Findings: prevalence 0·88% adult (>18 years) Shanghai, which increased age reached 6·70% at 80 years over. more prevalent women...
Background The COVID-19 pandemic has led to concerns around its subsequent impact on global health. Objective To investigate the health-seeking behavior, reflected by ECG utilization patterns, of patients with non-COVID-19 diseases during and after epidemic. Methods Taking advantage remote system covering 278 medical institutions throughout Shanghai, numbers visits examinations lockdown (between January 23 April 7, 2020), post-lockdown 8 December 31, 2020) post-SARS-CoV-2 2021) periods were...
Abstract Background The purpose of this study was to evaluate the clinical outcomes thoracic and lumbar spinal tuberculosis treated with isolated posterior instrumentation without radical debridement. Methods This retrospectively analyzed 73 patients who were using debridement in our hospital between January 2012 December 2019. patient group composed 42 men 31 women a mean age 67.3 ± 8.6 years. spine instability score (TSIS) used stability. All received chemotherapy for 18 months after...
The purpose of this study was to evaluate the effectiveness and safety long fusion (LF) versus short (SF) for treatment degenerative scoliosis (DS).We will search MEDLINE, EMBASE, PubMed, Cochrane Library, Web Science collect randomized non-randomized controlled studies that compared LF with SF in DS from inception June 1, 2019. quality included be assessed by 2 evaluation members according collaboration network standard or Newcastle-Ottawa Scale. analyzed using RevMan 5 (version 5.3.3).The...
Portal hypertension is a common complication of many chronic liver diseases and an important factor affecting the clinical prognosis patients. can bring series serious complications such as esophagogastric varices, gastrointestinal bleeding, ascites, spontaneous peritonitis, renal insufficiency, hypersplenism, hepatopulmonary syndrome. Hepatic venous pressure gradient best indicator that indirectly reflects portal pressure. Currently, it gold standard test for diagnosing clinically...
Objective To review our patients who underwent reconstruction of the defect after combined cranio-maxillo-facial resection in recent years.Methods From January,2005 to January,2011,88 resection.Different reconstructive techniques were used according classifications dura,skull base bone,and facial tissues.For dural defects,no repair (37 cases),primary closure (25 cases),and (26 cases) performed,respectively.Dural materials included thigh fascia lata (2 cases),temporalis cases),pericranium (1...
BackgroundThe residual device patency (RDP) after left atrial appendage closure (LAAC) with the LACbes has not been specifically explored in fibrillation (AF) patients. This study aims to explore incidence, impact and predictors of RDP detected by cardiac computed tomography angiography (CCTA) post LAAC.MethodsAF patients implanted were prospectively enrolled. CCTA surveillance was performed at 3 months post-procedure. Major adverse events (MAEs), including stroke/transient ischemic attack,...