- Infant Nutrition and Health
- Probiotics and Fermented Foods
- Proteins in Food Systems
- Animal health and immunology
- Protein Hydrolysis and Bioactive Peptides
- Fatty Acid Research and Health
- Animal Diversity and Health Studies
- Meat and Animal Product Quality
- COVID-19 and healthcare impacts
- Digestive system and related health
- Metabolomics and Mass Spectrometry Studies
- Lipid metabolism and biosynthesis
- Photochromic and Fluorescence Chemistry
- Atrial Fibrillation Management and Outcomes
- COVID-19 Clinical Research Studies
- Glycosylation and Glycoproteins Research
- 14-3-3 protein interactions
- Plant Physiology and Cultivation Studies
- Shape Memory Alloy Transformations
- Cardiac Arrhythmias and Treatments
- Mechanical Behavior of Composites
- Textile materials and evaluations
- Long-Term Effects of COVID-19
- Additive Manufacturing and 3D Printing Technologies
- Advanced Glycation End Products research
Xihua University
2025
Chengdu University
2023-2024
Shenyang Agricultural University
2019-2024
Guangdong Pharmaceutical University
2024
ShenZhen People’s Hospital
2024
Anhui Medical University
2017-2024
Università della Svizzera italiana
2024
University of California, San Diego
2023-2024
Second Hospital of Anhui Medical University
2017-2024
Beijing Tongren Hospital
2023
The sarcomeric interaction of α-myosin heavy chain (α-MHC) with Titin is vital for cardiac structure and contraction. However, the mechanism regulating this in normal failing hearts remains unknown. Lactate a crucial energy substrate heart. Here, we identify that α-MHC undergoes lactylation on lysine 1897 to regulate Titin. We observed reduction K1897 mice patients heart failure. Loss K1897R knock-in reduces α-MHC-Titin leads impaired function. Furthermore, identified p300 Sirtuin 1 act as...
Jinping Neutrino Experiment (Jinping) is proposed to significantly improve measurements on solar neutrinos and geoneutrinos in China Laboratory - a lab with number of unparalleled features, thickest overburden, lowest reactor neutrino background, etc., which identify it as the world-best low-energy laboratory. The experiment will have target mass 4 kilotons liquid scintillator or water-based scintillator, fiducial 2 for neutrino-electron scattering events 3 inverse-beta interaction events. A...
We report the enhanced photovoltaic properties in polycrystalline BiFeO3 (BFO) thin films with graphene as top electrodes. The short circuit current density (Jsc) and open voltage of heterojunction are measured to be 25 μA/cm2 0.44 V, respectively, much higher than reported values for BFO indium tin oxide (ITO) Influence HNO3 treatment on is studied, a significant photocurrent improvement from 2.8 mA/cm2 observed. A metal-intrinsic semiconductor-metal model proposed explain induced...
Aim: To evaluate the genetic associations of visceral adipose tissue (VAT) mass with metabolic risk factors and cardiovascular disease (CVD) endpoints to construct a network analysis about underlying mechanism using Mendelian randomization (MR) analysis. Methods Results: Using summary statistics from genome-wide association studies (GWAS), we conducted two-sample MR assess effects VAT on 10 53 CVD endpoints. Genetically predicted was associated factors, including triglyceride (odds ratio,...
This study investigated the impact of erythritol (ERY) on structural and functional properties whey protein isolate (WPI). FTIR CD revealed that WPI underwent changes, including formation β‐folds random coils, upon interaction with 20 mg/mL ERY. SEM showed increased surface roughness WPI, indicating enhanced exposure. Moreover, binding rate exceeded 85%, accompanied by hydrophobicity. Fluorescence spectroscopy indicated a red shift in fluorescence tyrosine (Tyr) residues, altering polarity...
The objective of the present study was to reveal antibacterial mechanism lactobionic acid (LBA) against methicillin-resistant Staphylococcus aureus (MRSA) using quantitative proteomics by sequential window acquisition all theoretical mass spectra (SWATH-MS) analyze 100 differentially expressed proteins after LBA treatment. Furthermore, multiple experiments were conducted validate results proteomic analysis including reactive oxygen species (ROS), virulence-associated gene expression, and...