Jianmin Li

ORCID: 0000-0002-0572-6324
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About
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Research Areas
  • Crop Yield and Soil Fertility
  • Rice Cultivation and Yield Improvement
  • Neurological Disease Mechanisms and Treatments
  • MicroRNA in disease regulation
  • Sperm and Testicular Function
  • Reproductive Biology and Fertility
  • Wheat and Barley Genetics and Pathology
  • CRISPR and Genetic Engineering
  • Plant Stress Responses and Tolerance
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Environmental and Agricultural Sciences
  • Plant nutrient uptake and metabolism
  • Silicon Effects in Agriculture
  • GABA and Rice Research
  • Heat shock proteins research
  • Molecular Biology Techniques and Applications
  • Calpain Protease Function and Regulation
  • RNA Research and Splicing
  • Soil Carbon and Nitrogen Dynamics
  • Plant responses to water stress
  • Ubiquitin and proteasome pathways
  • Signaling Pathways in Disease
  • Wastewater Treatment and Nitrogen Removal
  • Garlic and Onion Studies
  • Circular RNAs in diseases

Northwest A&F University
2024

Wenzhou Medical University
2010-2024

First Affiliated Hospital of Wenzhou Medical University
2010-2024

Model Animal Research Center
2016-2024

State Key Laboratory of Reproductive Medicine
2004-2024

Nanjing Medical University
2013-2024

Tongliao Academy of Agricultural Sciences
2024

Nanjing Agricultural University
2023-2024

Hunan Normal University
2024

Hunan Provincial People's Hospital
2015-2024

Free fatty acids induce apoptosis in cardiomyocytes, which is implicated lipotoxic cardiomyopathy. However, the underlying mechanisms remain not fully understood. MicroRNAs (miRNAs) are non-coding small RNAs that control gene expression at post-transcriptional level. Dysregulated miRNAs have been shown to be involved heart diseases. This study was examine whether miR-195 regulates palmitate-induced cardiomyocyte by targeting Sirt1, a known anti-apoptotic protein. In cultured neonatal mouse...

10.1093/cvr/cvr145 article EN Cardiovascular Research 2011-05-27

Jinping Neutrino Experiment (Jinping) is proposed to significantly improve measurements on solar neutrinos and geoneutrinos in China Laboratory - a lab with number of unparalleled features, thickest overburden, lowest reactor neutrino background, etc., which identify it as the world-best low-energy laboratory. The experiment will have target mass 4 kilotons liquid scintillator or water-based scintillator, fiducial 2 for neutrino-electron scattering events 3 inverse-beta interaction events. A...

10.1088/1674-1137/41/2/023002 article EN Chinese Physics C 2017-02-01

Mumps commonly affects children 5–9 yr of age, and can lead to permanent adult sterility in certain cases. However, the etiology this long-term effect remains unclear. infection results progressive degeneration seminiferous epithelium and, occasionally, Sertoli cell–only syndrome. Thus, remaining cells may be critical spermatogenesis recovery after orchitis healing. Here, we report that protein farnesylation/geranylgeranylation balance is for patients’ fertility. The expression...

10.1084/jem.20121806 article EN cc-by-nc-sa The Journal of Experimental Medicine 2013-07-01

Drought represents a key limiting factor of global crop distribution. Receptor-like kinases play major roles in plant development and defence responses against stresses such as drought. In this study, LRK2, which encodes leucine-rich receptor-like kinase, was cloned characterized found to be localized on the plasma membrane rice. Promoter-GUS analysis revealed strong expression tiller buds, roots, nodes anthers. Transgenic plants overexpressing LRK2 exhibited enhanced tolerance drought...

10.1111/pbi.12707 article EN cc-by Plant Biotechnology Journal 2017-02-09

A novel and accurate analytical method for the determination of tolfenpyrad in four leafy green vegetables, Brassica bara L., Spinacia oleracea Lactuca sativa L. chinensis was developed applied to investigate residue distribution dietary risk under greenhouse conditions. The established approach determined be adequate, with recoveries 79.2%-92.9% relative standard deviations < 8%. Tolfenpyrad dissipated relatively rapidly vegetables. Terminal residues were below 0.5 mg/kg (maximum limit set...

10.1016/j.fochx.2022.100241 article EN cc-by Food Chemistry X 2022-02-04

We investigated the effects of variety, planting density, and irrigation amount on grain yield, water-use efficiency (WUE), evapotranspiration (ETc). The trial was conducted in Tong Liao, Inner Mongolia, from 2021 to 2022, with compact variety Dika159 (DK159) conventional Zhengdan958 (ZD958) as test materials. density set 6.0 × 104 plants/ha (D1, local farmer density) 9.0 (D2), five levels: 450 mm (W450, used by farmers, CK); 360 (W360); 270 (W270); 180 (W180); 90 (W90). results indicate...

10.3390/agronomy14020400 article EN cc-by Agronomy 2024-02-19

Abstract An objective requirement of the sustainable utilization soil resources and agricultural production management is determination status salinization an understanding its dynamics. This study selected coastal plain, Yellow River flood key inland areas with in Shandong Province. Sampling analysis cultivated lands were conducted 2015–2016, 3,551 valid samples obtained. Statistical spatial analyses performed compared data from Second Soil Survey (1979–1985). The degree, area,...

10.1002/ldr.3236 article EN Land Degradation and Development 2018-12-04

Abstract Background Bacterial blight (BB), caused by Xanthomonas oryzae pv. ( Xoo ) is one of the most devastating bacterial diseases rice in temperate and tropical regions. Breeding deployment resistant cultivars carrying major resistance R genes has been effective approach for BB management. However, because specific interaction each gene with product corresponding pathogen avirulence or effector gene, new strains that can overcome deployed often emerge rapidly. To deal ever-evolving , it...

10.1186/s12284-021-00462-3 article EN cc-by Rice 2021-02-27

This study explored the role of fibulin-3 in osteosarcoma progression and possible signaling pathway involved. Fibulin-3 mRNA protein expression normal tissue, benign fibrous dysplasia, osteosarcoma, cell lines (HOS U-2OS), osteoblastic line hFOB, different invasive subclones was evaluated by immunohistochemistry (IHC) or immunocytochemistry (ICC) real time reverse transcriptase-polymerase chain reaction (real qRT-PCR). To assess invasion metastasis cells, lentiviral vectors with small...

10.1038/s41598-017-06353-2 article EN cc-by Scientific Reports 2017-07-18

Abstract Background Oral squamous cell carcinoma (OSCC) is one of the most prevalent and fatal oral cancers. Mitochondria-targeting therapies represent promising strategies against various cancers, but their applications in treating OSCC are limited. Alantolactone (ALT) possesses anticancer properties also regulates mitochondrial events. In this study, we explored effects ALT on related mechanisms. Methods The cells were treated with varying concentrations duration N -Acetyl- l -cysteine...

10.1186/s12967-023-04188-2 article EN cc-by Journal of Translational Medicine 2023-05-18

The piRNA pathway is essential for female fertility in golden hamsters and likely humans, but not mice. However, the role of individual PIWIs mammalian reproduction remains poorly understood outside Here, we describe expression profiles, subcellular localization, knockout-associated reproductive defects all four hamsters. In hamsters, PIWIL1 PIWIL3 are highly expressed throughout oogenesis early embryogenesis, while knockout leads to sterility, deficiency results subfertility with lagging...

10.1038/s41467-023-40650-x article EN cc-by Nature Communications 2023-08-29

Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal tract, but molecular mechanisms underlying IBD are incompletely understood. In this study, we explored role and regulating mechanism otubain 2 (OTUB2), deubiquitinating enzyme, in IBD.

10.1002/ctm2.70038 article EN cc-by Clinical and Translational Medicine 2024-10-01
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