Shuang Gao

ORCID: 0000-0003-2012-8768
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About
Contact & Profiles
Research Areas
  • Pesticide and Herbicide Environmental Studies
  • Weed Control and Herbicide Applications
  • Synthesis and Biological Evaluation
  • Synthesis and biological activity
  • Electrospun Nanofibers in Biomedical Applications
  • Allelopathy and phytotoxic interactions
  • Fungal Plant Pathogen Control
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Click Chemistry and Applications
  • Quinazolinone synthesis and applications
  • Photosynthetic Processes and Mechanisms
  • Polymer-Based Agricultural Enhancements
  • Microwave-Assisted Synthesis and Applications
  • Pesticide Exposure and Toxicity
  • Conducting polymers and applications
  • Glutathione Transferases and Polymorphisms
  • Synthesis and Reactions of Organic Compounds
  • Analytical Chemistry and Chromatography
  • Molecular Sensors and Ion Detection
  • Antimicrobial agents and applications
  • Nanocomposite Films for Food Packaging
  • Synthesis of Organic Compounds
  • Chemical Reaction Mechanisms
  • Metal-Catalyzed Oxygenation Mechanisms
  • Enzyme Catalysis and Immobilization

Northeast Agricultural University
2016-2025

Education Department of Heilongjiang Province
2025

Innovation Academy for Microsatellites of Chinese Academy of Sciences
2022-2024

Shanghai Micro Satellite Engineering Center
2022-2024

Xi'an City Planning&Design Institute (China)
2024

Collaborative Innovation Center of Chemistry for Energy Materials
2024

University of Science and Technology of China
2024

Shanghai Jiao Tong University
2023

Jining Medical University
2023

Peking University
2022-2023

Crystallization orientation plays a crucial role in determining the performance and stability of perovskite solar cells (PVSCs), whereas effective strategies for realizing oriented crystallization is still lacking. Herein, facile efficient top-down strategy reported to manipulate via treating wet film with propylamine chloride (PACl) before annealing. The PA

10.1002/adma.202313524 article EN Advanced Materials 2024-03-08

Protoporphyrinogen oxidase (PPO, EC 1.3.3.4) is an important target for discovering novel herbicides, and it causes bleaching symptoms by inhibiting the synthesis of chlorophyll heme. In this study, active fragments several commercial herbicides were joined substructure splicing bioisosterism, a series diphenyl ether derivatives containing five-membered heterocycles synthesized. The greenhouse herbicidal activity PPO inhibitory in vitro discussed detail. results showed that most compounds...

10.1021/acs.jafc.1c05210 article EN Journal of Agricultural and Food Chemistry 2022-01-18

Mitochondrial dysfunction is a hallmark of heart failure. transplantation has been demonstrated to be able restore function, but its mechanism action remains unresolved. Using an in-house optimized mitochondrial isolation method, we tested efficacy mitochondria in two different failure models. First, using doxorubicin-induced model, demonstrate that before doxorubicin challenge protects cardiac function vivo and prevents myocardial apoptosis, contraction improvement relies on the metabolic...

10.1016/j.ymthe.2023.02.016 article EN cc-by-nc-nd Molecular Therapy 2023-02-20

4-Hydroxyphenylpyruvate dioxygenase (HPPD, EC 1.13.11.27) is an important target site for discovering new bleaching herbicides. To explore novel HPPD inhibitors with excellent herbicidal activity, a series of N-aroyl diketone/triketone derivatives were rationally designed by splicing active groups and bioisosterism. Bioassays revealed that most these displayed preferable activity against Echinochloa crus-galli (EC) at 0.045 mmol/m2 Abutilon juncea (AJ) 0.090 mmol/m2. In particular, compound...

10.1021/acs.jafc.9b01412 article EN Journal of Agricultural and Food Chemistry 2019-10-07

Tribenuron-methyl (TM), as one of the sulfonylurea (SU) herbicides, has been widely and effectively applied for many kinds plants. SUs inhibit plant growth by restraining biosynthetic pathway branched-chain amino acids (BCAAs) catalyzed acetolactate synthase (ALS). Safeners are agrochemicals that protect crops from herbicide injuries. To improve crop tolerance under TM toxicity stress, this paper evaluated protective effect N-tosyloxazolidine-3-carboxamide. It turned out most tested...

10.1021/acs.jafc.9b03587 article EN Journal of Agricultural and Food Chemistry 2019-10-04

To seek new protoporphyrinogen oxidase (PPO) inhibitors with better biological activity, a series of novel diphenyl ether derivatives containing tetrahydrophthalimide were designed based on the principle substructure splicing and bioisomerization. PPO inhibition experiments exhibited that 6c is most potential compound, half-maximal inhibitory concentration (IC50) value 0.00667 mg/L, showing 7 times higher activity than Oxyfluorfen (IC50 = 0.0426 mg/L) against maize similar herbicidal...

10.1021/acs.jafc.0c00947 article EN Journal of Agricultural and Food Chemistry 2020-03-03

Abstract BACKGROUND Thiabendazole (TBZ) is a poorly water‐soluble benzimidazole fungicide. However, the water solubility of TBZ can be significantly enhanced by inclusion complexation with cyclodextrins. In this study, thiabendazole/hydroxypropyl‐ β ‐cyclodextrin (TBZ/HP CD) complex was synthesized and electrospinning performed to produce TBZ/HP CD nanofibrous CD‐NF) that improved antifungal activity. RESULTS The formation CD‐NF characterized Fourier transform infrared spectroscopy, X‐ray...

10.1002/ps.5885 article EN Pest Management Science 2020-05-07

Herbicide safeners selectively protect crops from herbicide damage without reducing the herbicidal efficiency on target weed species. The title compounds were designed by intermediate derivatization approach and fragment splicing to exploit novel potential safeners. A total of 31 diazabicyclo derivatives synthesized microwave-assistant method using isoxazole-4-carbonyl chloride derivatives. All synthetic confirmed infrared, 1H 13C nuclear magnetic resonance, high-resolution mass...

10.1021/acs.jafc.9b07449 article EN Journal of Agricultural and Food Chemistry 2020-02-26

Herbicide safeners enhance herbicide detoxification in crops without reducing their herbicidal efficacy against target weeds. To alleviate maize injury caused by the sulfonylurea nicosulfuron, a series of 1,3-disubstituted imidazolidine or hexahydropyrimidine derivatives were rationally designed via bioisosterism and active subunit combinations. Thirty novel compounds synthesized using an efficient one-pot method low-cost raw materials characterized IR, 1H NMR, 13C high-resolution mass...

10.1021/acs.jafc.0c04436 article EN Journal of Agricultural and Food Chemistry 2020-12-29

Fenoxaprop-p-ethyl (FE), a type of acetyl-CoA carboxylase (ACCase) inhibitor, has been extensively applied to variety crop plants. It can cause damage wheat (Triticum aestivum) even resulting in the death crop. On prerequisite not reducing herbicidal efficiency on target weed species, herbicide safeners selectively protect crops from injury. Based fragment splicing, series novel substituted pyrazole derivatives was designed ultimately address phytotoxicity caused by FE. The title compounds...

10.1021/acs.jafc.1c02221 article EN Journal of Agricultural and Food Chemistry 2021-07-26
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