Yafei Zhang

ORCID: 0000-0003-2130-847X
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About
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Research Areas
  • Meat and Animal Product Quality
  • Plant Stress Responses and Tolerance
  • Mycotoxins in Agriculture and Food
  • Speech and Audio Processing
  • Protein Hydrolysis and Bioactive Peptides
  • Plant nutrient uptake and metabolism
  • Magnesium Alloys: Properties and Applications
  • Proteins in Food Systems
  • Plant Molecular Biology Research
  • Corrosion Behavior and Inhibition
  • Advanced Cellulose Research Studies
  • Plant-Microbe Interactions and Immunity
  • Polysaccharides Composition and Applications
  • Cancer-related gene regulation
  • Asymmetric Hydrogenation and Catalysis
  • Zeolite Catalysis and Synthesis
  • Plant responses to water stress
  • Advanced biosensing and bioanalysis techniques
  • Biochemical effects in animals
  • Genomics and Phylogenetic Studies
  • RNA modifications and cancer
  • MicroRNA in disease regulation
  • Advanced Data Compression Techniques
  • Collagen: Extraction and Characterization
  • Circular RNAs in diseases

China Agricultural University
2023-2025

Guiyang Medical University
2025

Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences
2025

Shanxi Agricultural University
2024

Tianjin University of Science and Technology
2021-2024

Xi'an Jiaotong University
2022-2024

Anhui Agricultural University
2018-2024

Jiangnan University
2024

Capital University of Economics and Business
2023

Wenzhou Medical University
2023

Drug-induced liver injury (DILI) is a major clinical issue associated with the majority of commercial drugs. During DILI, peroxynitrite (ONOO-) level upregulated in liver. However, traditional methods are unable to timely monitor dynamic changes ONOO- during DILI vivo. Therefore, ONOO--activated near-infrared (NIR) fluorescent probes high sensitivity and selectivity key early diagnosis situ. Herein, we report novel ONOO--responsive NIR probe, QCy7-DP, which incorporates donor-dual-acceptor...

10.1021/acs.analchem.3c00007 article EN Analytical Chemistry 2023-03-23

The development of supramolecular hosts with effective host–guest properties is crucial for their applications. Herein, we report the preparation a porphyrin-based metallacage, which serves as host series polycyclic aromatic hydrocarbons (PAHs). association constant between metallacage and coronene reaches 2.37 × 107 M–1 in acetonitrile/chloroform (ν/ν = 9/1), among highest values metallacage-based complexes. Moreover, exhibits good singlet oxygen generation capacity, can be further used to...

10.1021/jacsau.2c00245 article EN cc-by-nc-nd JACS Au 2022-06-01

ABSTRACT With advancing age, the decline in intestinal stem cell (ISC) function can lead to a series of degenerative changes epithelium, critical factor that increases risk diseases elderly. Consequently, there is an urgent imperative devise effective dietary intervention strategies target alterations senescent ISCs alleviate senescence‐related dysfunction. The 28‐month‐old naturally aging mouse model was utilized discover primary contributing compromised barrier and digestive absorption...

10.1111/acel.70052 article EN cc-by Aging Cell 2025-04-01

Abstract: Here, we report the hypoxia-responsive ionizable liposomes to deliver small interference RNA (siRNA) anticancer drugs, which can selectively enhance cellular uptake of siRNA under hypoxic and low-pH conditions cure glioma. For this purpose, malate dehydrogenase lipid molecules were synthesized, contain nitroimidazole groups that impart hypoxia sensitivity specificity as hydrophobic tails, tertiary amines hydrophilic head groups. These molecules, together with DSPE-PEG2000...

10.2147/ijn.s125286 article EN cc-by-nc International Journal of Nanomedicine 2017-02-01

In strawberry, sucrose is the major form of carbohydrate translocated from leaves to fruits and plays an important role in fruit ripening. As a conserved energy sensor, nonfermenting-1 (SNF1)-related kinase 1 (SnRK1) plant carbon metabolism. However, evidence that SnRK1 regulates accumulation lacking. this study, we transiently expressed FaSnRK1α strawberry found overexpression (OE) gene significantly increased content, whereas repression by RNA interference (RNAi) decreased content. Further...

10.1016/j.plaphy.2020.03.044 article EN cc-by-nc-nd Plant Physiology and Biochemistry 2020-04-02

Recently, circular RNAs (circRNAs) have been frequently reported to be involved in hepatocellular carcinoma (HCC) development and progression. However, the role of circRNAs hepatic fibrosis (HF) is still unclear. Our previous high-throughput screen revealed changes many mice with carbon tetrachloride (CCl4)-induced HF. For instance, expression circPSD3, a circRNA derived from Pleckstrin Sec7 domain-containing 3 (PSD3) gene, was considerably downregulated primary stellate cells (HSCs) liver...

10.1016/j.omtn.2021.01.007 article EN cc-by-nc-nd Molecular Therapy — Nucleic Acids 2021-01-18

Abstract Aerogel fibers are thermally insulating and can be woven, so they expected to form a new generation of smart textiles that efficiently reduce heat consumption. However, producing continuous aerogel have the necessary strength toughness woven remains great challenge. Herein, with aid freeze‐thaw treatment poly(vinyl alcohol) (PVA) solution freeze‐spinning technology, PVA an aligned porous morphology prepared in large‐scale. Freeze–thaw greatly contributes improving spinnability...

10.1002/mame.202100399 article EN Macromolecular Materials and Engineering 2021-08-13

BACKGROUND The authors built a model for lung cancer diagnosis previously based on the blood biomarkers progastrin‐releasing peptide (ProGRP), carcinoembryonic antigen (CEA), squamous cell carcinoma (SCC), and cytokeratin 19 fragment (CYFRA21‐1). In current study, they examined whether modification of to include relevant clinical information, risk factors, low‐dose chest computed tomography screening would improve performance biomarker panel in large cohorts Chinese adults. METHODS study was...

10.1002/cncr.31020 article EN Cancer 2017-09-20

It is very important to promote root growth and delay leaf senescence, improve nitrogen absorption utilization efficiency, the storage nutrition level of tree, so as fruit quality yield peach. In this experiment, we compared analyzed effects traditional fertilization bag-controlled release fertilizer (BCRF) on shoots roots, senescence leaves quality. Moreover, impacts BCRF ammonia volatilization, rate, fine turnover, plant nutrients were also investigated. Compared with conventional use,...

10.3389/fpls.2021.627313 article EN cc-by Frontiers in Plant Science 2021-03-31

Abstract Background Oral squamous cell carcinoma (OSCC) is one of the most prevalent and fatal oral cancers. Mitochondria-targeting therapies represent promising strategies against various cancers, but their applications in treating OSCC are limited. Alantolactone (ALT) possesses anticancer properties also regulates mitochondrial events. In this study, we explored effects ALT on related mechanisms. Methods The cells were treated with varying concentrations duration N -Acetyl- l -cysteine...

10.1186/s12967-023-04188-2 article EN cc-by Journal of Translational Medicine 2023-05-18
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