A5072337296- Advanced Fiber Optic Sensors
- Photonic and Optical Devices
- Advanced Fiber Laser Technologies
- Photonic Crystal and Fiber Optics
- Cancer Immunotherapy and Biomarkers
- Computational Drug Discovery Methods
- Cancer-related molecular mechanisms research
- Mechanical and Optical Resonators
- Optical Network Technologies
- Optical Coherence Tomography Applications
- Advanced Chemical Sensor Technologies
- Electromagnetic wave absorption materials
- Asthma and respiratory diseases
- Aluminum Alloy Microstructure Properties
- Ovarian cancer diagnosis and treatment
- Semiconductor Lasers and Optical Devices
- Solidification and crystal growth phenomena
- Traditional Chinese Medicine Studies
- Histone Deacetylase Inhibitors Research
- Ferroptosis and cancer prognosis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Acupuncture Treatment Research Studies
- IL-33, ST2, and ILC Pathways
- Immunotherapy and Immune Responses
- S100 Proteins and Annexins
Jiangsu Province Hospital
2023-2025
Nanjing Medical University
2022-2025
Harbin Medical University
2020-2024
China North Industries Group Corporation (China)
2024
Northwestern Polytechnical University
2013-2023
Yahoo (United Kingdom)
2023
Brocade (United States)
2022
Weatherford College
2022
Beijing Institute of Technology
2013-2019
Beijing Institute of Optoelectronic Technology
2013-2018
The oncogene Aurora kinase A (AURKA) has been implicated in various tumor, yet its role meningioma remains unexplored. Recent studies have suggested a potential link between AURKA and ferroptosis, although the underlying mechanisms are unclear. This study presented evidence of upregulation high grade ability to enhance malignant characteristics. We identified as suppressor erastin-induced ferroptosis meningioma. Mechanistically, directly interacted with phosphorylated kelch-like...
Regulation of the oxidative stress response is crucial for management and prognosis traumatic brain injury (TBI). The copper chaperone Antioxidant 1 (Atox1) plays a role in regulating intracellular ion balance impacting antioxidant capacity mitochondria, as well state cells. However, it remains unknown whether Atox1 involved modulating following TBI. Here, we investigated regulatory on neurons both vivo vitro, elucidated underlying mechanism through culturing hippocampal HT-22 cells with...
In this paper, the thermo-optic coefficient of silica fiber is analyzed and measured within a wide temperature range 0-1200 °C for first time. To obtain coefficient, experiments were carried out by using optic extrinsic Fabry-Perot interferometers (EFPIs) embedded in fiber. The optical cavity lengths EFPIs with white-light interferometry. experimental results show that second orders are 1.090 × 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML"...
A self-temperature-calibrated gas pressure sensor with a sandwich structure made of single-mode fiber (SMF)-hollow core (HCF)-SMF is proposed and experimentally demonstrated. Fabry-Perot interferometer (FPI) formed by the SMF-HCF-SMF along axial direction, an antiresonant reflecting optical waveguide (ARROW) ring-cladding HCF radial direction. micro-channel drilled on using femtosecond laser to facilitate air entering/exiting HCF. The FPI functions as sensor, ARROW temperature sensor....
A compact optical fiber sensor based on a Fabry–Perot interferometer (FPI) with an integrated Bragg grating is proposed to measure pressure and temperature simultaneously. The light reflectors of the FPI comprise graphene film end face. sensitivities for measuring are 501.4 nm/kPa 306.2 nm/°C, respectively. Conflicting signals can cause cross-impact errors at 610 Pa/°C. introduction effectively prevent sensor. sensitivity obtained 7.96 12 times higher than previous study. simultaneously using matrix.
Untargeted metabolomics based on liquid chromatography–mass spectrometry is affected by nonlinear batch effects, which cover up biological result in nonreproducibility, and are difficult to be calibrate. In this study, we propose a novel deep learning model, called Normalization Autoencoder (NormAE), autoencoders (AEs) adversarial learning. An additional classifier ranker trained provide regularization during the training of AE latent representations extracted encoder, then decoder...
Background: Resveratrol has been found to have anti-inflammatory and anti-allergic properties. The effects of resveratrol on thymic stromal lymphopoietin (TSLP)-mediated atopic march remain unclear. Purpose: To explore the potential role in TSLP-mediated march. Methods: mouse model was established by topical application MC903 (a vitamin D3 analog). Following treatment with resveratrol, airway resistance mice discovered pulmonary function apparatus, number total cells, neutrophils,...
Alleviating the multiple types of programmed neuronal death caused by mechanical injury has been an impetus for designing neuro-therapeutical approaches after traumatic brain (TBI). The aim this study was to elucidate potential role PSMD14 (proteasome 26S subunit, non-ATPase 14) in neuron and specific mechanism through which it improves prognosis TBI patients. Here, we identified differential expression protein between controlled cortical impact (CCI) sham mouse groups LC-MS proteomic...
A fiber-optic dual-cavity Fabry-Perot interferometric sensor for the simultaneous measurement of temperature and pressure is proposed experimentally demonstrated. The cascades a intrinsic interferometer (IFPI) an extrinsic (EFPI). IFPI used as EFPI sensor. based on diaphragm-free structure can work stably at high temperature. Two optical path differences are interrogated simultaneously by using fast Fourier transform-based white-light interferometry peak-to-peak method. Experimental results...
A fiber-optic hybrid sensor based on dual-cavity Fabry-Perot interferometers is proposed and demonstrated for the simultaneous measurement of high temperature pressure. The fabricated by fusion splicing two single-mode fibers (SMFs), a hollow core fiber (HCF), coreless (CF), forming four-section structure leading SMF-SMF-HCF-CF. micro-hole at end SMF using femtosecond laser, an air gap between SMFs. CF thinned roughened laser to form diaphragm. SMF-based cavity used as HCF-based pressure...
A three-wavelength passive demodulation technique to interrogate extrinsic Fabry-Perot interferometric (EFPI) sensors with arbitrary cavity length has been developed. The DC component is obtained online, then the applied dynamic signal recovered by using three new signals without component. performance of demonstrated simulations and experiments. can extract signals, regardless whether phase modulation larger than 2π. Theoretically, EFPI be demodulated technique, lengths in 22.96-1002.3 μm...
A novel polarization splitter based on photonic crystal fibers (PCFs) with two nonidentical cores is proposed. The highly birefringent are vertically arranged to obtain selective coupling. horizontal exchanges its energy between the cores. However, vertical shows little coupling This achieved in single-material glass waveguides for first time our knowledge. PCF-based exhibits many advantages such as shorter length, high extinction ratio, and wide bandwidth over counterparts.
The polarization dependence of light coupling in photonic crystal fibers (PCFs) with sixfold symmetric dual cores and highly birefringent are numerically investigated. characteristics PCF-based couplers, such as length, extinction ratio form birefringence, examined functions the air-hole size pitch. silica bridges between air holes take an important role energy transfer across two cores. We believe that mechanism couplers is different from conventional waveguide couplers. dependent can be...
A dual-wavelength DC compensation technique for the demodulation of extrinsic Fabry-Perot interferometric (EFPI) fiber sensors is developed. The can overcome two problems in measurement: cavity length EFPI and wavelengths light sources must be matched, component fringe eliminated. proposed verified by demodulating with different lengths phase modulations. Experimental results show that interrogate an sensor any modulation. Besides, has properties high frequency, large dynamic range, sensitivity.
A compact microhole-induced fiber optic inline Mach–Zehnder interferometer (MZI) is demonstrated for measurements of refractive index (RI) and magnetic field. Inline MZIs with different etched diameters, interaction lengths sizes microholes are fabricated assessed. The optical transmission spectra the immersed into a series liquids characterized analysed. Experimental results show that liquid RI sensitivity as high 539.8436 nm RIU−1 in range 1.3352–1.4113 RIU achieved also exhibits good...
A diaphragm-free fiber gas pressure sensor based on the extrinsic Fabry-Perot interferometer (EFPI) is proposed and experimentally demonstrated. The fabricated by fusion splicing a sandwich structure of single mode fiber, hollow core (HCF), coreless fiber. femtosecond (fs) laser employed to drill micro-channel side wall HCF allow entering/exiting HCF. refractive index has linear relationship with pressure. Thus, can be detected investigating optical path difference EFPI. experimental results...
Abstract An on-fiber extrinsic Fabry–Perot interferometric (EFPI) vibration sensor based on micro-cantilever beam is proposed and experimentally demonstrated. The beam, with a cantilever length of 80μm thickness 5μm, created perpendicular to the fiber axis by using femtosecond laser micro-machining technique. has same diameter that single mode fiber. acceleration sensitivity 11.1 mV/g@300 Hz in range 0.5-5g demonstrated experimentally. This design allows for be smaller size higher...