A5100769024- Sepsis Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Cardiac Arrest and Resuscitation
- Chronic Kidney Disease and Diabetes
- Renal Diseases and Glomerulopathies
- Mesenchymal stem cell research
- Antibiotic Use and Resistance
- Long-Term Effects of COVID-19
- Heart Rate Variability and Autonomic Control
- Radiomics and Machine Learning in Medical Imaging
- Antibiotic Resistance in Bacteria
- Lung Cancer Diagnosis and Treatment
- COVID-19 and healthcare impacts
- Cardiovascular Function and Risk Factors
- Intensive Care Unit Cognitive Disorders
- Cardiac electrophysiology and arrhythmias
- Gastric Cancer Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Thermal Regulation in Medicine
- COVID-19 diagnosis using AI
- Lipid metabolism and disorders
- Liver Disease Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Cardiac Valve Diseases and Treatments
- Respiratory Support and Mechanisms
Capital Medical University
2018-2025
Qilu Hospital of Shandong University
2015-2025
Shandong University
2015-2025
Beijing Tian Tan Hospital
2018-2025
Shanghai University of Traditional Chinese Medicine
2011-2025
First People's Hospital of Chongqing
2024-2025
Chongqing University
2020-2025
Huazhong University of Science and Technology
2020-2025
Air Force Medical University
2016-2025
First Affiliated Hospital of Dalian Medical University
2018-2025
<h3>Importance</h3> Secondary hyperparathyroidism contributes to extraskeletal calcification and is associated with all-cause cardiovascular mortality. Control suboptimal in the majority of patients receiving hemodialysis. An intravenously (IV) administered calcimimetic could improve adherence reduce adverse gastrointestinal effects. <h3>Objective</h3> To evaluate relative efficacy safety IV etelcalcetide oral cinacalcet. <h3>Design, Setting, Participants</h3> A randomized, double-blind,...
Electrospun hybrid nanofibers prepared using combinations of natural and synthetic polymers have been widely investigated in cardiovascular tissue engineering. In this study, electrospun gelatin/polycaprolactone (PCL) collagen/poly(l-lactic acid-co-ε-caprolactone) (PLCL) scaffolds were successfully produced. Scanning electron micrographs showed that fibers both membranes smooth homogeneous. Water contact angle measurements further demonstrated hydrophilic. To determine cell attachment...
Background Urinary tract infections (UTIs) are one of the most common worldwide, but little is known about their global scale and long-term trends. We aimed to estimate spatiotemporal patterns UTIs' burden along with its attributable risk factors at a level, as well variations burdens according socio-demographic status, regions, nations, sexes, ages, which may be helpful in guiding targeted prevention treatment programs. Methods Data from Global Burden Disease Study 2019 were analyzed depict...
Abstract On the basis of Covid-19-induced pulmonary pathological and vascular changes, we hypothesize that anti-vascular endothelial growth factor (VEGF) drug bevacizumab might be beneficial for treating Covid-19 patients. From Feb 15 to April 5, 2020, conducted a single-arm trial (NCT04275414) recruited 26 patients from 2-centers (China Italy) with severe Covid-19, respiratory rate ≥30 times/min, oxygen saturation ≤93% ambient air, or partial arterial pressure fraction inspiration O 2 ratio...
The regeneration and repair of articular cartilage remains a major challenge for clinicians scientists due to the poor intrinsic healing this tissue. Since injuries are often clinically irregular, tissue-engineered scaffolds that can be easily molded fill defects any shape fit tightly into host needed.In study, bone marrow mesenchymal stem cell (BMSC) affinity peptide sequence PFSSTKT (PFS)-modified chondrocyte extracellular matrix (ECM) particles combined with GelMA hydrogel were...
Background: The prognostic significance of serum albumin levels in patients with sepsis has previously been reported; however, these studies have not excluded the potential confounding effect exogenous administration. In this study, we investigate predictive value for prognosis severe without interference Methods: A prospective cohort study was conducted from April to November 2014 internal and surgical intensive care units a tertiary hospital. During period, due supply shortage, were...
To investigate the different CT characteristics which may distinguish influenza from 2019 coronavirus disease (COVID-19).A total of 13 confirmed patients with COVID-19 were enrolled January 16, 2020, to February 25, 2020. Furthermore, 92 scans pneumonia, including 76 A and 16 B, scanned between 1, 2019, retrospectively reviewed. Pulmonary lesion distributions, number, attenuation, lobe predomination, margin, contour, ground-glass opacity involvement pattern, bronchial wall thickening, air...
Aberrant endoplasmic reticulum (ER) stress and autophagy are associated with diabetic nephropathy. Here we investigated the effect of astragaloside IV (AS-IV) on progression nephropathy (DN) underlying mechanism involving ER in streptozotocin (STZ)-induced mice high glucose (HG)-incubated podocytes. The developed progressive albuminuria glomerulosclerosis within 8 weeks, which were significantly ameliorated by AS-IV treatment a dose-dependent manner. Moreover, diabetes or HG-induced podocyte...
We report a human case of viral encephalitis caused by pseudorabies virus (PRV) in China. A 43-year-old man with no previous medical history presented high-grade fever, headache and tonic-clonic seizures as well coma. Plain computer tomography (CT) brain imaging showed hypo-density the bilateral basal ganglia, occipital lobe, limbic left thalamic. Next-generation sequencing (NGS) confirmed presence PRV cerebral spinal fluid (CSF). Regular polymerase chain reaction (PCR) was applied to...
We aimed to estimate the spatiotemporal patterns of encephalitis burden along with its attributable risk factors at national, regional, and global levels, which may be helpful in guiding targeted prevention treatment programs.Based on available data sources, incidence, mortality, disability-adjusted life years (DALYs) 204 countries regions from 1990 2019 were reconstructed by Global Burden Disease Study using Cause Death Ensemble model, Gaussian process regression, DisMod-MR 2.1. conducted a...
Abstract Background The role of systemic inflammation in promoting cardiovascular diseases has attracted attention, but its correlation with various arrhythmias remains to be clarified. We aimed comprehensively assess the association between indicators and atrial fibrillation/flutter (AF), ventricular arrhythmia (VA), bradyarrhythmia UK Biobank cohort. Methods After excluding ineligible participants, a total 478,524 eligible individuals (46.75% male, aged 40–69 years) were enrolled study...
Adrenal medullary chromaffin cells are a potential source of neuroactive substances for transplantation into the CNS to alleviate neurochemical deficits. In particular, work in our laboratory has suggested that adrenal transplants spinal subarachnoid space can pain by providing sustained local delivery catecholamines and opioid peptides. One major limitations clinical application neural is availability donor material sufficient quantities. This limitation may be overcome use xenogeneic...
Background: Recently, surgical apgar score (SAS) has been reported to be strongly associated with major morbidity after abdominal surgery. The aim of this study was assess the value esophagectomy SAS (eSAS) in predicting risk open a high volume cancer center.
Abstract: Electrospinning has recently received considerable attention, showing notable potential as a novel method of scaffold fabrication for cartilage engineering. The aim this study was to use coculture strategy chondrocytes combined with electrospun gelatin/polycaprolactone (GT/PCL) membranes, instead pure chondrocytes, evaluate the formation cartilaginous tissue. We prepared GT/PCL seeded bone marrow stromal cell (BMSC)/chondrocyte cocultures (75% BMSCs and 25% chondrocytes) in...
Hemorrhagic shock may contribute to acute kidney injury (AKI) by profoundly altering renal mitochondrial function. Resveratrol (RSV), a naturally occurring sirtuin 1 (SIRT1) activator, has been shown promote function and reduce oxidative damage in variety of aging-related disease states. We hypothesized that RSV treatment during resuscitation would ameliorate dysfunction decrease following hemorrhagic shock.Using decompensated model, male Long-Evans rats (n = 6 per group) were killed prior...
The authors examined the acceptability and feasibility of telehealth services shortly after their rapid introduction into a community behavioral health agency as part response to COVID-19 pandemic.
// Wei-dong Qin 1 , Guo-liang Liu 2 Juan Wang 3 Hao Jian-ning Zhang Fan Yang Ma Xin-ying Ji Chen Li and Ming-xiang 4 Department of Critical Care Medicine, Qilu Hospital Shandong University, Jinan, Shandong, China The Henan Provincial Key Engineering Laboratory Antibody Drugs, School Kaifeng, Henan, Cardiology, Second Cardiovascular Remodeling Function Research, Chinese Ministry Education Public Health, Correspondence to: Qin, email: Zhang, Keywords : diabetic cardiomyopathy, poly(ADP-ribose)...
Dachshund homolog 1 (DACH1), a key cell-fate determinant, regulates transcription by DNA sequence–specific binding. We identified diminished Dach1 expression in large-scale screen for mutations that convert injury-resistant podocytes into injury-susceptible podocytes. In diabetic kidney disease (DKD) patients, podocyte DACH1 levels are diminished, condition strongly correlates with poor clinical outcomes. Global KO mice manifest renal hypoplasia and die perinatally. Podocyte-specific mice,...