A5080252318- Multiple Sclerosis Research Studies
- Influenza Virus Research Studies
- Vaccine Coverage and Hesitancy
- Data-Driven Disease Surveillance
- Health disparities and outcomes
- Bacterial Infections and Vaccines
- Pneumonia and Respiratory Infections
- Primary Care and Health Outcomes
- Chronic Disease Management Strategies
- Respiratory viral infections research
- Systemic Sclerosis and Related Diseases
- Emergency and Acute Care Studies
- Systemic Lupus Erythematosus Research
- Birth, Development, and Health
- Health Promotion and Cardiovascular Prevention
- Assisted Reproductive Technology and Twin Pregnancy
- Injury Epidemiology and Prevention
- Diabetes Management and Education
- Public Health Policies and Education
- Viral gastroenteritis research and epidemiology
- Herpesvirus Infections and Treatments
- Trauma and Emergency Care Studies
- Salmonella and Campylobacter epidemiology
- Gestational Diabetes Research and Management
- Health Systems, Economic Evaluations, Quality of Life
University of Alberta
2014-2023
University of Calgary
2014-2023
Alberta Health
2014-2023
Government of Alberta
2005-2023
Ministry of Health
2006-2022
University of Waterloo
2022
General Department of Preventive Medicine
2018-2021
Alberta Health Services
2005-2021
McGill University
2012-2016
University of Manitoba
2013-2016
Previously, we have demonstrated a high incidence and prevalence of Crohn's disease (CD) ulcerative colitis (UC) in the Canadian province Manitoba. However, epidemiology inflammatory bowel (IBD) other regions Canada has not been defined. The aim this study was to estimate CD UC diverse overall burden IBD Canada.We applied common case identification algorithm, previously validated Manitoba provincial health databases British Columbia (BC), Alberta (AB), Saskatchewan (SK), (MB), Nova Scotia...
Abstract Introduction Severe acute renal failure (sARF) is associated with considerable morbidity, mortality and use of healthcare resources; however, its precise epidemiology long-term outcomes have not been well described in a non-specified population. Methods Population-based surveillance was conducted among all adult residents the Calgary Health Region (population 1 million) admitted to multidisciplinary cardiovascular surgical intensive care units between May 1999 April 30 2002....
Studies of achalasia epidemiology are important as they often yield new insights into disease etiology. In this study, our objective was to carry out the first North American population-based study using a governmental administrative database.All residents in province Alberta, Canada receive universal healthcare coverage benefit. The provincial health ministry, Alberta Health and Wellness, maintains central stakeholder database patient demographic information physician billing claims. We...
<b><i>Background:</i></b> The risk of stroke is elevated in the first 48 hours after TIA. Previous prognostic models suggest that diabetes mellitus, age, and clinical symptomatology predict stroke. authors evaluated magnitude predictors TIA an entire population over time. <b><i>Methods:</i></b> Administrative data from four different databases were used to define for province Alberta fiscal year (April 1999–March 2000). age-adjusted incidence was estimated using direct standardization 1996...
Abstract Objective To estimate the effectiveness of mRNA covid-19 vaccines against symptomatic infection and severe outcomes (hospital admission or death). Design Test negative design study. Setting Ontario, Canada between 14 December 2020 19 April 2021. Participants 324 033 community dwelling people aged ≥16 years who had symptoms were tested for SARS-CoV-2. Interventions BNT162b2 (Pfizer-BioNTech) mRNA-1273 (Moderna) vaccine. Main outcome measures Laboratory confirmed SARS-CoV-2 by reverse...
To evaluate the direct and indirect influences of physical comorbidity, symptoms depression anxiety, fatigue, disability on health-related quality life (HRQoL) in persons with multiple sclerosis (MS).A large (n = 949) sample adults MS was recruited from 4 Canadian clinics. HRQoL assessed using patient-reported Health Utilities Index Mark 3. Expanded Disability Status Scale scores, depression, fatigue were evaluated as predictors a cross-sectional path analysis.All significantly associated...
Low income appears to be associated with a higher prevalence of diabetes and related complications, however, little is known about how influences access care. The objective the present study was determine whether referral centre within universal health care system.
Objective. This study quantified the impact of delayed childbearing (maternal age ≥35 years) on population rate changes in low birth weight (LBW; &lt;2500 g), preterm delivery (&lt;37 weeks), multiple births, and small for gestational (SGA; &lt;10th percentile) Alberta, Canada, between 1990 (N = 42 930) 1996 37 710). Methods. Data were obtained from provincial notification a live or stillbirth. Analyses included relative risk estimates χ2 tests trend. Potential confounding...
Temporal trends in risk factors for cardiovascular disease and the impact of socio-economic status on these remain unclear.
The purpose of this study was to identify key demographic and health factors associated with physical activity (PA) participation in adults type 1 or 2 diabetes.Participants were > = 18 yr age living the province Alberta, Canada who previously diagnosed (N 697) 1614) diabetes. Individuals recruited from Canadian Diabetes Association (Alberta) registry through a random digit-dialing protocol. Multiple logistic regression models employed related PA levels, which many date have not been...
ABSTRACT: Objectives: To describe the incidence and pattern of traumatic spinal cord injury cauda equina (SCI) in a geographically defined region Canada. Methods: The study period was April 1, 1997 to March 31, 2000. Data were gathered from three provincial sources: administrative data Alberta Ministry Health Wellness, records Trauma Registry, death certificates Office Medical Examiner. Results: From all sources, 450 cases SCI identified. Of these, 71 (15.8%) died prior hospitalization....
Objective. We describe the frequency and patterns of injury affecting 96 359 children between 0 10 years old living in Alberta, Canada. Design. This population-based, longitudinal study involved born 3 fiscal April 1, 1985 to March 31, 1988, recruited before age who remained until at least 5. used International Classification Diseases, Ninth Revision, Clinical Modification chapter-17 diagnostic codes provided by physicians. Codes were grouped into 17 categories; episodes calculated, age-...
In 2000, Ontario, Canada, initiated a universal influenza immunization program (UIIP) to provide free vaccines for the entire population aged 6 mo or older. Influenza increased more rapidly in younger age groups Ontario compared other Canadian provinces, which all maintained targeted programs. We evaluated effect of Ontario's UIIP on influenza-associated mortality, hospitalizations, emergency department (ED) use, and visits doctors' offices.
To date, no study has examined influenza vaccine effectiveness (IVE) against laboratory-confirmed influenza-associated hospitalizations during pregnancy. The Pregnancy Influenza Vaccine Effectiveness Network (PREVENT) consisted of public health or healthcare systems with integrated laboratory, medical, and vaccination records in Australia, Canada (Alberta Ontario), Israel, the United States (California, Oregon, Washington). Sites identified pregnant women aged 18 through 50 years whose...
While mental comorbidity is considered common in multiple sclerosis (MS), its impact poorly defined; methods are needed to support studies of comorbidity. We validated and applied administrative case definitions for any comorbidities MS. Using health data we identified persons with MS a matched general population cohort. Administrative comorbidity, mood disorder, depression, anxiety, bipolar disorder schizophrenia were developed against medical records using kappa statistic (k). these...
Province-wide population-based administrative health data from British Columbia (BC), Canada (population: approximately 4.5 million) were used to estimate the incidence and prevalence of multiple sclerosis (MS) examine potential trends over time. All BC residents meeting validated case definitions for MS identified using hospital, physician, death, registration files. Estimates annual (1991–2008), (1996–2008; allowing a 5-year disease-free run-in period) age sex standardized 2001 Canadian...
Background: Despite the importance of comorbidity in multiple sclerosis (MS), methods for assessment MS are poorly developed. Objective: We validated and applied administrative case definitions diabetes, hypertension, hyperlipidemia MS. Methods: Using provincial data we identified persons with a matched general population cohort. Case were derived using hospital, physician, prescription claims, 430 examined temporal trends age-adjusted prevalence these conditions from 1984–2006. Results:...
<h3>Objective:</h3> To determine the prevalence of comorbidity in multiple sclerosis (MS) population at time MS diagnosis. We also compared to that a matched cohort from general population. <h3>Methods:</h3> Using population-based administrative health data 4 Canadian provinces, we identified 23,382 incident cases and 116,638 age-, sex-, geographically controls. estimated hypertension, diabetes, hyperlipidemia, heart disease, chronic lung epilepsy, fibromyalgia, inflammatory bowel...
To evaluate the association between comorbidity and relapse rate in individuals with multiple sclerosis (MS).We recruited prevalent relapsing-onset MS from 4 Canadian Clinics to participate a 2-year prospective multicenter cohort study involving cross-sectional assessment of comorbidities relapses. Comorbidities were recorded using questionnaires, relapses captured medical records at each visit. The baseline over subsequent follow-up period was examined Poisson regression, adjusting for age,...
Summary Background Medical therapy is standard treatment for ulcerative colitis with colectomy reserved medically refractory disease or malignancy. The introductions of ciclosporin in 1994 and anti‐ TNF 2005 have extended medical management options. Aim To determine whether the incidence rate has changed since introduction therapy. Methods Adult patients a diagnosis who subsequently underwent an urgent elective Edmonton, Canada between 1 January 1998 31 December 2011 were identified....
Objective: To describe the regional distribution of multiple sclerosis (MS) prevalence in Canada, controlling for age and sex. Methods: This study used data from Canadian Community Health Survey, a large general health survey (n=131,535) conducted 2000/2001. Subjects aged 18 over were included current analysis (n=116,109). The presence MS was determined by self-report. Prevalence computed five regions (Atlantic, Quebec, Ontario, Prairies British Columbia). Logistic regression to compare...
The association between injurious falls requiring a visit to the emergency department and various classes of medications was examined in case-control study community living persons aged 66 years older.Administrative databases from an urban health region provided information used. Five controls for each case were randomly selected dwelling older who had not reported fall one six regional departments year. Two series analyses on medication use within 30 days conducted using logistic...
Background: Ethnic disparities in access to health care and outcomes are well documented. It is unclear whether similar differences exist between Aboriginal non-Aboriginal people with chronic kidney disease Canada. We determined differed status (Aboriginal registered under the federal Indian Act) disease. Methods: identified 106 511 1182 patients (estimated glomerular filtration rate less than 60 mL/min/1.73 m2). compared outcomes, including hospital admissions, that may have been...