A5034701753- Health disparities and outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Primary Care and Health Outcomes
- Healthcare Policy and Management
- Chronic Disease Management Strategies
- Palliative Care and End-of-Life Issues
- Geriatric Care and Nursing Homes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Global Health Care Issues
- Vaccine Coverage and Hesitancy
- Smoking Behavior and Cessation
- Migration, Health and Trauma
- Diabetes Management and Education
- Health Promotion and Cardiovascular Prevention
- Influenza Virus Research Studies
- Nutritional Studies and Diet
- Frailty in Older Adults
- SARS-CoV-2 detection and testing
- Obesity, Physical Activity, Diet
- Global Health Workforce Issues
- Food Security and Health in Diverse Populations
- Emergency and Acute Care Studies
- Cardiovascular Health and Risk Factors
- COVID-19 epidemiological studies
- Global Public Health Policies and Epidemiology
Ottawa Hospital Research Institute
2016-2025
Ottawa Hospital
2016-2025
University of Ottawa
2016-2025
Bruyère
2016-2025
Statistics Canada
2016-2025
Institute for Clinical Evaluative Sciences
2015-2024
Government of Canada
2022-2024
Children's Hospital of Eastern Ontario
2020-2024
Wilfrid Laurier University
2023
McMaster University
2021-2023
OBJECTIVE The definition of obesity (BMI ≥30 kg/m2), a key risk factor diabetes, is widely used in white populations; however, its appropriateness nonwhite populations has been questioned. We compared the incidence rates diabetes across white, South Asian, Chinese, and black identified equivalent ethnic-specific BMI cutoff values for assessing risk. RESEARCH DESIGN AND METHODS conducted multiethnic cohort study 59,824 nondiabetic adults aged years living Ontario, Canada. Subjects were from...
Rates of obesity and diabetes have increased substantially in recent decades; however, the potential role built environment mitigating these trends is unclear.To examine whether walkable urban neighborhoods are associated with a slower increase overweight, obesity, than less ones.Time-series analysis (2001-2012) using annual provincial health care (N ≈ 3 million per year) biennial Canadian Community Health Survey 5500 cycle) data for adults (30-64 years) living Southern Ontario...
The majority of immigrants to Canada originate from the developing world, where most rapid increase in prevalence diabetes mellitus is occurring. We undertook a population-based study involving Ontario, Canada, evaluate distribution risk for this population.We used linked administrative health and immigration records calculate age-specific age-adjusted rates among men women aged 20 years or older 2005. compared 1,122,771 Ontario by country region birth long-term residents province. logistic...
The risk of inflammatory bowel disease (IBD) contributed by the environment can be elucidated assessing in migrants from low prevalence to Western countries. incidence IBD immigrants Canada and their Canadian-born children was compared with nonimmigrants.A population-based cohort patients derived health administrative data linked immigration determine standardized Ontario, Canada, region birth between 1994 2010. hazard younger age at determined. Incidence for Ontario-born immigrant mothers...
Health administrative data is increasingly being used for chronic disease surveillance. This study explored agreement between and survey ascertainment of seven key diseases, using individually linked from a large population individuals in Ontario, Canada. All adults who completed any one three cycles the Canadian Community Survey (2001, 2003 or 2005) agreed to have their responses provincial health were included. The sample included 85,549 persons. Previously validated case definitions...
As people diagnosed with HIV and receiving combination antiretroviral therapy are now living longer, they likely to acquire chronic conditions related normal ageing the effects of its treatment. Comordidities for have not previously been described from a representative population perspective.
International cohort studies have reported increased incidence of inflammatory bowel disease (IBD) in recent years, and Canada has among the highest rates IBD world. This study assessed prevalence Ontario, most populous province Canada, to determine changing trends age onset.We used a population-based derived from validated health administrative data consisting all Ontario residents living with 1999 2008. We determined over time using Poisson regression analysis, assessing 10-year groups,...
Ontario, the most populous province in Canada, has a universal healthcare system that routinely collects health administrative data on its 13 million legal residents is used for research. Record linkage become vital tool this research by enriching with Immigration, Refugees and Citizenship Canada Permanent Resident (IRCC-PR) database Office of Registrar General's Vital Statistics-Death (ORG-VSD) registry. Our objectives were to estimate rates compare characteristics individuals linked versus...
Optimal performance is critical for decision-making tasks from medicine to autonomous driving, however common measures may be too general or specific. For binary classifiers, diagnostic tests prognosis at a timepoint, such as the area under receiver operating characteristic curve, precision recall are because they include unrealistic decision thresholds. On other hand, accuracy, sensitivity F1 score single threshold that reflect an individual probability predicted risk, rather than range of...
Importance Despite public health concerns that cannabis legalization may increase the number of cases schizophrenia caused by cannabis, there is limited evidence on this topic. Objective To examine changes in population-attributable risk fraction (PARF) for use disorder (CUD) associated with after liberalization medical and nonmedical Canada. Design, Setting, Participants This population-based cohort study was conducted Ontario, Canada, from January 1, 2006, to December 31, 2022, among 13...
Temporal trends in risk factors for cardiovascular disease and the impact of socio-economic status on these remain unclear.
Background Coordinated and appropriate health care across sectors is an ongoing challenge, especially at the end-of-life. Population-level data on end-of-life use cost, however, are seldom reported a comprehensive array of sectors. Such will identify level being provided areas where can be optimized. Methods This retrospective cohort study identified all deaths in Ontario from April 1, 2010 to March 31, 2013. Using population-based administrative databases, we examined cost last year life....
In 2000, Ontario, Canada, initiated a universal influenza immunization program (UIIP) to provide free vaccines for the entire population aged 6 mo or older. Influenza increased more rapidly in younger age groups Ontario compared other Canadian provinces, which all maintained targeted programs. We evaluated effect of Ontario's UIIP on influenza-associated mortality, hospitalizations, emergency department (ED) use, and visits doctors' offices.
<b>Aim:</b> To examine neighbourhood income differences in deaths amenable to medical care and public health over a 25-year period after the establishment of universal insurance for doctors hospital services Canada. <b>Methods:</b> Data census metropolitan areas were obtained from Canadian Mortality Database population censuses years 1971, 1986, 1991 1996. Deaths care, health, ischaemic heart disease other causes considered. on grouped into quintiles basis tract percentage below Canada's...
Behaviours such as smoking, poor diet, physical inactivity, and unhealthy alcohol consumption are leading risk factors for death. We assessed the Canadian burden attributable to these behaviours by developing, validating, applying a multivariable predictive model of all-cause death.A algorithm 5 y death-the Mortality Population Risk Tool (MPoRT)-was developed validated using 2001 2008 Community Health Surveys. There were approximately 1 million person-years follow-up 9,900 deaths in...
Use of routinely collected electronic health data to identify people for epidemiology studies and performance reports can lead serious bias
Abstract Background In classification and diagnostic testing, the receiver-operator characteristic (ROC) plot area under ROC curve (AUC) describe how an adjustable threshold causes changes in two types of error: false positives negatives. Only part AUC are informative however when they used with imbalanced data. Hence, alternatives to have been proposed, such as partial precision-recall curve. However, these cannot be fully interpreted AUC, because ignore some information about actual...
Depression is strongly linked to increased mortality in individuals with type 2 diabetes. Despite high rates of co-occurring anxiety and depression, the risk death associated comorbid diabetes poorly understood. This study documented excess symptoms depression and/or diabetes.Using data for 64,177 Norwegian adults from second wave Nord-Trøndelag Health Study (HUNT2), linkage Causes Death Registry, we assessed all-cause survey participation 1995 through 2013. We used Cox proportional hazards...