A5100639155- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- HIV Research and Treatment
- Sex work and related issues
- Adolescent Sexual and Reproductive Health
- HIV/AIDS drug development and treatment
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Cardiovascular Health and Disease Prevention
- Syphilis Diagnosis and Treatment
- Cytomegalovirus and herpesvirus research
- Birth, Development, and Health
- Cerebrovascular and Carotid Artery Diseases
- Nutritional Studies and Diet
- LGBTQ Health, Identity, and Policy
- HIV-related health complications and treatments
- Blood Pressure and Hypertension Studies
- Mobile Health and mHealth Applications
- Pneumocystis jirovecii pneumonia detection and treatment
- Stroke Rehabilitation and Recovery
- Obesity, Physical Activity, Diet
- Medication Adherence and Compliance
- Neuroinflammation and Neurodegeneration Mechanisms
- Herpesvirus Infections and Treatments
- Intracerebral and Subarachnoid Hemorrhage Research
Beijing Center for Disease Prevention and Control
2015-2024
Center for Disease Control
2011-2024
Guangxi Center for Disease Prevention and Control
2010-2024
Ningxia Medical University
2023
National Center for AIDS/STD Control and Prevention,China CDC
2021
Huazhong University of Science and Technology
2017-2018
Tianjin Medical University General Hospital
2015-2018
Chinese Center For Disease Control and Prevention
2016
Tianjin Medical University
2015
Centers for Disease Control and Prevention
2011-2014
Real-time adherence monitoring is now possible through medication storage devices equipped with cellular technology. We assessed the effect of triggered cell phone reminders and counseling using objective data on antiretroviral therapy (ART) among Chinese HIV-infected patients.We provided ART patients in Nanning, China, a device (Wisepill) to monitor their electronically. After 3 months, we randomized subjects within optimal (≥95%) suboptimal (<95%) strata intervention vs. control arms. In...
Abstract Human immunodeficiency virus (HIV) sexual transmission among men who have sex with (MSM) has increased markedly in Beijing, China the past decade. Pre-exposure prophylaxis (PrEP) is a highly efficacious biomedical prevention strategy that remarkably reduces HIV-transmission risk. This study examined PrEP awareness MSM and factors influencing it. From April to July 2021, respondent-driven sampling was used conduct cross-sectional survey China. Demographic, behavior, data regarding...
Objectives Undiagnosed HIV presents great potential for the spread of infection. The authors identify prevalence and correlates never testing being unaware infection in Beijing men who have sex with (MSM). Methods Cross-sectional biological behavioural survey using respondent-driven sampling; 500 MSM were included. Results was 7.2% 86.1% their infection; 33.2% had tested. Never associated lower educational (adjusted odds ratio (AOR) 1.6, 95% CI (CI) 1.1 to 2.5), living ≤3 years (AOR 1.5, 1.0...
Diagnosis of HIV is the entry point into continuum care; a well-recognized necessary condition for ultimate prevention onward transmission. In China, testing rates among men who have sex with (MSM) are low compared to other high risk subgroups, yet experiences MSM in China not well understood. To address this gap and prepare intervention development promote rapid linkage treatment, six focus groups (FGs) were conducted Beijing (40 HIV-positive participated one four FGs 20 HIV-negative or...
We assessed HIV prevalence and associated behaviors risk factors among men who have sex with (MSM) in Beijing, China. Five hundred MSM were recruited for a biological behavioral survey using respondent-driven sampling (RDS) 2009. Serologic specimens tested markers of syphilis infection. A computer-assisted personal interview (CAPI) administered questionnaire gathered information including demographic characteristics, sexual behaviors, testing, social norms concerning condom use. The adjusted...
Objective: Our objective was to explore the effect of depression and anxiety on adherence antiretroviral therapy (ART) among MSM with newly diagnosed HIV infections. Design: We conducted a prospective study Chinese Methods: The Hospital Anxiety Depression Scale used measure at baseline, 6 12 months, separately. ART self-reported once every 3 months ('perfect' or no missing dose in past vs. 'imperfect' least one months). utilized priori substantial knowledge guided by causal models identify...
Depression and anxiety are common among persons recently diagnosed with HIV infection. We examined whether depression or was associated delayed initiation of antiretroviral therapy (ART) a prospective cohort Chinese men who have sex (MSM) were newly HIV. The Hospital Anxiety Scale (HADS) used for measuring anxiety, scores 0–7, 8–10, 11–21 representing normal, borderline, likely, respectively. ART information extracted from the National Database. Cox regression performed to assess...
Background and Purpose— Although stroke in the young middle aged accounts for 31% of all strokes China, disease burden is unknown. We aimed to determine secular trends incidence transition subtypes rural China over a 24-year period. Methods— In 1992, 14 920 residents were recruited participate Tianjin Brain Study. Stroke events deaths registered annually. assessed first-ever stroke, including intracerebral hemorrhage ischemic among adults 35 64 years during 1992 1999, 2000 2007, 2008 2015....
The HIV epidemic among men who have sex with (MSM) has been increasing at an alarming rate in most areas of China recent years. Many Chinese MSM still lack sufficient access to prevention services, despite ongoing scale-up comprehensive testing and intervention services. purpose this study was investigate utilization related factors that influence the people test or other services prevent Beijing, China. Three successive cross-sectional surveys were conducted Beijing from September 2009...
Background Sexual transmission of HIV among men who have sex with (MSM) increased markedly in China during the past decade. incidence is a critical indicator surveillance and we use HIV-1 BED-capture-enzyme immunoassay (BED-CEIA) to examine MSM Beijing from 2008 2016. Risk factors related recent infection were also assessed. Methods Consecutive cross-sectional surveys on conducted yearly through Demographic behaviors data collected. status was determined positive specimens tested for using...
Objective To project the HIV/AIDS epidemics among men who have sex with (MSM) under different combinations of HIV testing and linkage to care (TLC) interventions including antiretroviral therapy (ART) in Beijing, China. Design Mathematical modeling. Methods Using a mathematical model fit prevalence estimates from 2000–2010, we projected trends incidence during 2011–2020 five scenarios: (S1) current intervention levels by averaging 2000–2010 coverage; (S2) increased ART coverage TLC; (S3)...
Background Various studies have modeled the impact of test-and-treat policies on HIV epidemics worldwide. However, few modeling taken into account China’s context. To understand potential effect epidemic among men who sex with (MSM) in China, we developed a mathematical model to evaluate strategy. Method Based natural history CD4 count people living and AIDS (PLWHA), constructed dynamic compartmental transmission Chinese MSM project number new infections prevalence over 10 years. We...
Background This study investigated HIV and syphilis incidence among men who have sex with (MSM) in Beijing, China. Methods An open cohort was established from September 2009 to April 2012. Participants were followed up every three four months after recruitment for thirty-one total. Chi-square tests used compare demographic behavioral characteristics between participants those lost follow up. Univariate multivariate Cox proportional hazards regression analyses examine associations incidence....
Background: The HIV epidemic continues to expand among men who have sex with (MSM) in China. NIMH Project Accept/HPTN 043 trial suggested a borderline significant trend toward incidence reduction persons higher testing rates. Methods: We assessed histories and infection status community-based Beijing MSM. serostatus was lab confirmed. ascertained demographic/behavioral factors through questionnaire-based interviews. Associations of previous odds current were assessed, seeking improved...
To explore the epidemic history of HIV-1 CRF01_AE in China, 408 fragments gag gene sequences sampled 2002–2010 were determined from different geographical regions and risk populations China. Phylogenetic analysis indicates that can be grouped into four clusters, suggesting at least genetically independent descendants are circulating which two closely related to isolates Thailand Vietnam. Cluster 1 has most extensive distribution In North cluster 4 mainly transmitted through homosexuality.The...
This study assessed the changes of HIV incidence and its predictors among Beijing’s men who have sex with (MSM). Three consecutive cross-sectional surveys were carried out using a consistent respondent-driven sampling (RDS) approach in 2009, 2010, 2011, respectively. Structured-questionnaire based interviews completed computer-assisted self-administration. Incident infection was examined BED capture enzyme immunoassay (BED-CEIA). The overall rate prevalence 8.0% three years (95% confidence...
Abstract Carotid intima-media thickness (CIMT) is an established predictor of cardiovascular disease and stroke. However, risk factors associated with CIMT remain unclear. Therefore, we aimed to identify in a low-income Chinese population. Stroke-free disease-free residents aged ≥45 years were recruited. B-mode ultrasonography was performed measure CIMT. The mean age participants (n = 3789) 59.92 overall, 61.13 men, 59.07 women (P < 0.001). Male sex, older age, low education level,...