A5100453450- Cancer survivorship and care
- Acupuncture Treatment Research Studies
- Dialysis and Renal Disease Management
- Cancer Treatment and Pharmacology
- Complementary and Alternative Medicine Studies
- Acute Lymphoblastic Leukemia research
- HER2/EGFR in Cancer Research
- Medical Research and Treatments
- Orthopaedic implants and arthroplasty
- Spine and Intervertebral Disc Pathology
- Palliative Care and End-of-Life Issues
- CAR-T cell therapy research
- Lung Cancer Treatments and Mutations
- Management of metastatic bone disease
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Bone health and treatments
- Hip and Femur Fractures
- Childhood Cancer Survivors' Quality of Life
- Lung Cancer Diagnosis and Treatment
- Gout, Hyperuricemia, Uric Acid
- Healthcare and Venom Research
- Cancer-related cognitive impairment studies
- Traditional Chinese Medicine Studies
- Nausea and vomiting management
- Breast Cancer Treatment Studies
Charles Darwin University
2020-2025
Peking Union Medical College Hospital
2023-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2025
Shanghai Jiao Tong University
2014-2025
University of Shanghai for Science and Technology
2025
Renji Hospital
2016-2025
Third Xiangya Hospital
2025
Central South University
2017-2025
University of Southern Queensland
2025
Yan'an University
2025
Fatigue and diarrhea are the most frequent adverse effects of pelvic radiotherapy, while their etiologies largely unknown. The aim this study is to investigate correlations between fatigue, diarrhea, alterations in gut microbiota induced by radiotherapy. During 5-week treatment radiotherapy 11 cancer patients, general fatigue score significantly increased was more prominent patients with diarrhea. closely correlated decrease serum citrulline (an indicator functional enterocyte mass)...
In addition to the controversy regarding association of hyperuricemia with mortality, uncertainty also remains between low serum uric acid (SUA) and mortality. We aimed assess relationship SUA all-cause cause-specific mortality.This cohort study included 9118 US adults from National Health Nutrition Examination Survey (1999-2002). Multivariable Cox proportional hazards models were used evaluate Our analysis use a generalized additive model smooth curve fitting (penalized spline method),...
Rapid detection of allelic variation and identification advantage haplotypes responsible for spike related traits play a crucial role in wheat yield improvement. The released genome sequence hexaploid (Chinese Spring) provides an extraordinary opportunity rapid natural promotes breeding application. Here, selection signals genome-wide association study (GWAS) were conducted traits. Based on the genotyping results by 90K SNP chip, 192 common samples from southwest China analyzed. One hundred...
Background: Optimal treatment strategy for nonagenarians and centenarians with hip fractures (NCHF) remained unknown. We aimed to compare the outcomes of surgical conservative management in NCHF. Methods: A prospective cohort study was conducted based on CPMHF database NCHF patients hospitalized during 2014–2020. Comorbidities were evaluated by mECM score restricted cubic spline utilized visually assess dose-effect relationship between outcomes. Propensity matching performed balance baseline...
Attaining complete remission of acute lymphoblastic leukemia (ALL) before hematopoietic stem cell transplantation (HSCT) correlates with better post-transplant outcomes. Inotuzumab ozogamicin (InO), an anti-CD22 antibody conjugated to calicheamicin, has shown significantly higher rates remission, minimal residual disease negativity, and HSCT versus standard chemotherapy in treating relapsed/refractory (R/R) ALL. We investigated the role previous transplant proceeding directly after as...
Abstract Adults with relapsed/refractory acute lymphoblastic leukemia (R/R ALL) have a poor prognosis, especially if disease burden is high. This post hoc analysis of the phase 3 INO-VATE trial examined efficacy and safety inotuzumab ozogamicin (InO) vs. standard care chemotherapy (SC) among R/R ALL patients low, moderate, or high burden, respectively, defined as bone marrow blasts (BMB) < 50% ( n = 53 48), 50–90% 79 83), >90% 30 30). Patients in InO SC arm BMB%, had improved rates...
Abstract Background Previous studies of primarily Western populations have reported contrasting associations dairy consumption with certain cancers, including a positive association prostate cancer and inverse colorectal premenopausal breast cancers. However, there are limited data from China where rates levels differ importantly those in populations. Methods The prospective Kadoorie Biobank study recruited ~0.5 million adults ten diverse (five urban, five rural) areas across during...
Femoral head necrosis is a rare but devastating complication following femoral neck fracture. The reported incidence of avascular after fracture fixation varies widely, and there no consensus regarding its risk factors. aim this study was to analyze the factors for internal in This retrospective included 166 patients with fractures treated surgical reduction at authors’ institution from January 2004 December 2008. Eight died reasons unrelated surgery, 12 were lost follow-up. remaining 146...
BACKGROUND Inotuzumab ozogamicin (InO) has demonstrated efficacy and tolerability in patients aged 18 to 78 years with relapsed/refractory acute lymphoblastic leukemia (ALL) the INO‐VATE trial. This subset analysis compared safety of InO younger older patients. METHODS Intent‐to‐treat analyses morphologic responses overall survival (OS) included 326 randomized patients, assessments 307 receiving 1 or more doses study treatment. Of 164 received at a starting dose 1.8 mg/m 2 /cycle (0.8 on day...
Abstract Background The relevance of folic acid for stroke prevention in low-folate populations such as China is uncertain. Genetic studies the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism, which increases plasma homocysteine (tHcy) levels, could clarify causal elevated tHcy levels stroke, ischaemic heart disease (IHD) and other diseases without fortification. Methods In prospective Kadoorie Biobank, 156 253 participants were genotyped MTHFR 12 240 developed a during...