- Folate and B Vitamins Research
- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Nutrition and Health in Aging
- Cardiovascular Health and Disease Prevention
- Artificial Intelligence in Healthcare
- Blood Pressure and Hypertension Studies
- Vitamin C and Antioxidants Research
- Alcoholism and Thiamine Deficiency
- Birth, Development, and Health
- Gastric Cancer Management and Outcomes
- Radiomics and Machine Learning in Medical Imaging
- Nutritional Studies and Diet
- Inflammatory Biomarkers in Disease Prognosis
- Chromium effects and bioremediation
- GDF15 and Related Biomarkers
- Antioxidant Activity and Oxidative Stress
- Children's Physical and Motor Development
- Heavy metals in environment
- Frailty in Older Adults
- Advanced Data Processing Techniques
- Pharmacology and Obesity Treatment
- Infrared Thermography in Medicine
- Apelin-related biomedical research
- Safety and Risk Management
Inner Mongolia University of Technology
2025
Southern Medical University
2016-2024
Nanfang Hospital
2016-2024
Harvard University
2021-2023
Institute of Electrical and Electronics Engineers
2023
Antea Group (France)
2023
Engineering Systems (United States)
2023
University of Memphis
2023
Nanchang University
2022
Duke University
2018-2021
In addition to the controversy regarding association of hyperuricemia with mortality, uncertainty also remains between low serum uric acid (SUA) and mortality. We aimed assess relationship SUA all-cause cause-specific mortality.This cohort study included 9118 US adults from National Health Nutrition Examination Survey (1999-2002). Multivariable Cox proportional hazards models were used evaluate Our analysis use a generalized additive model smooth curve fitting (penalized spline method),...
Pulse wave velocity (PWV) has been shown to influence the effects of antihypertensive drugs in prevention cardiovascular diseases. Data are limited on whether PWV is an independent predictor stroke above and beyond hypertension control. This longitudinal analysis examined joint effect brachial-ankle (baPWV) with control risk first stroke. report included 3310 hypertensive adults, a subset China Stroke Primary Prevention Trial (CSPPT) baseline measurements for baPWV. During median follow-up...
The main purpose of academic warning is to promptly detect students' learning crises during the teaching process, and provide effective intervention, thereby achieving supervision entire process by teachers students effectively improving quality learning. author used method data comparison analysis conduct a detailed comparative collection source processing methods, algorithm evaluation result methods in methods. Then, an was conducted on machine learning, linear regression, artificial...
Background: Previous studies support an association between elevated total homocysteine (tHcy) levels and increased all-cause mortality. However, few prospective have examined this in hypertensive patients, and/or tested any effect modification by the methylene tetrahydrofolate reductase (MTHFR) C677T genotype. Methods: This was a post hoc analysis of China Stroke Primary Prevention Trial. Serum tHcy folate were measured at baseline. Individual MTHFR genotype (CC, CT, TT) determined....
Abstract We aimed to investigate the association of brachial–ankle pulse wave velocity (baPWV) with carotid plaque presence and number in a Chinese hypertensive population. A total 13,554 subjects from China Stroke Primary Prevention Trial (CSPPT) were recruited. Arterial stiffness evaluated by baPWV B-mode ultrasonography, respectively. Multivariate logistic regression analysis was used determine correlation presence. Multinomial number. Further interactions between examined using subgroup...
Serum choline levels were associated with multiple chronic diseases. However, the association between serum and all-cause mortality in Chinese adults hypertension remains unclear. The purpose of this study is to explore concentrations risk hypertension, a high-risk population.A nested, case-control was conducted that included 279 patients death, matched, living controls, derived from China Stroke Primary Prevention Trial (CSPPT). Baseline measured by liquid chromatography tandem quadrupole...
Stroke is a major global health burden, and risk prediction essential for the primary prevention of stroke. However, uncertainty remains about optimal model analyzing stroke risk. In this study, we aim to determine most effective method in Chinese hypertensive population using machine learning establish general methodological pipeline future analysis.The training set included 70% data (n = 14,491) from China Primary Prevention Trial (CSPPT). Internal validation was processed with rest 30%...
Tobacco smoking is a major known risk factor for lung cancer. While micronutrients, especially those involved in maintaining DNA integrity and regulating gene expression, may be protective, research on this association limited. This report aimed to investigate associations of total folate, 5-methyltetrahydrofolate (5-mTHF) vitamin B12 with incident cancer, whether the vary by status. A nested case-control study 490 cancer cases controls matched age (±1 year), sex, residence, center, drawn...
Aim: To date, findings on the overall and sex-specific effects of plasma pyridoxal 5′-phosphate (PLP, active coenzyme form vitamin B6) risk coronary heart disease (CHD) have been inconsistent. This study sought to advance our understanding association PLP with CHD, particular attention paid sex differences effect modifiers. Methods: We conducted a hospital-based, case-control suspected CHD patients undergoing diagnostic angiography. A total 429 cases controls matched by age, sex, operation...
<title>Abstract</title> Background Gastric cancer (GC) remains a major challenge in oncology due to its late diagnosis and poor prognosis. Predicting Vascular Endothelial Growth Factor (VEGF) levels survival outcomes accurately can significantly enhance therapeutic decision-making. This study introduces an innovative approach utilizing [18F] FDG PET/CT radiomics predict VEGF status outcomes, aiming improve personalized treatment strategies GC. Methods We performed retrospective analysis of...
Background Vitamin K plays a role in preventing vascular calcification and may have synergetic influence with vitamin D on cardiovascular health. However, whether this relationship applies to stroke, especially high-risk population of hypertensive individuals, remains unclear. The present study aims the joint association low K1 status first stroke general adults. Methods This used nested, case–control design data from China Stroke Primary Prevention Trial. analysis included 604 total...
Background Mortality is one of the most fundamental metrics population health. The role nutrition in reducing mortality great public health interest. High levels homocysteine (HHcy, part, due to low folate intake) are known increase risk cardiovascular diseases. However, data limited on longitudinal association HHcy with all‐cause regions such as China. Objective In a relatively intake and high rate HHcy, we aimed test hypothesis that associated increased folic acid therapy can reduce HHcy....
Background: The association between plasma vitamin E levels and first stroke risk in men women remains unclear. Objective: We aimed to examine the prospective stroke, evaluate effect modifiers for association, among hypertensive patients. Design: study sample was drawn from China Stroke Primary Prevention Trial (CSPPT), which randomized a total of 20,702 patients double-blind, daily treatment with either 10 mg enalapril 0.8 folic acid or alone. This nested case-control study, including 618...
OBJECTIVE: Obtain pilot data to explore whether transpinal direct current stimulation (tsDCS) administered in association with locomotor training, could increase training-dependent learning. BACKGROUND: Adequate gait is required for daily living and impaired brain spinal cord disorders. Locomotor training the gold standard of neurorehabilitation; however recovery usually incomplete. It would be important develop strategies improve beneficial effects on function. DESIGN/METHODS: In this...
Background Pulse wave velocity (PWV) has been shown to affect the effects of anti‐hypertensive treatment in prevention cardiovascular diseases. Data are very limited regarding whether PWV is an independent predictor stroke above and beyond hypertension control. In their current guidelines for management arterial hypertension, European Society Hypertension included as a potential consideration managing middle‐aged hypertensive patients with increased aortic stiffness. However, none have...