A5053030535- Nutrition and Health in Aging
- Frailty in Older Adults
- Body Composition Measurement Techniques
- Inflammatory Biomarkers in Disease Prognosis
- Cancer, Lipids, and Metabolism
- Parasitic infections in humans and animals
- Aldose Reductase and Taurine
- Nutritional Studies and Diet
- Cancer Risks and Factors
- Cancer Immunotherapy and Biomarkers
- Immune Cell Function and Interaction
- Liver Disease Diagnosis and Treatment
- Childhood Cancer Survivors' Quality of Life
- Clinical Nutrition and Gastroenterology
- RNA modifications and cancer
- Prenatal Substance Exposure Effects
- GDF15 and Related Biomarkers
- Advancements in Solid Oxide Fuel Cells
- Biochemical effects in animals
- Esophageal and GI Pathology
- RNA Research and Splicing
- Pancreatic and Hepatic Oncology Research
- T-cell and B-cell Immunology
- Plant Physiology and Cultivation Studies
- Ferroptosis and cancer prognosis
Daping Hospital
2015-2025
First People's Hospital of Yunnan Province
2009-2025
Army Medical University
2015-2025
Hangzhou Center for Disease Control and Prevention
2024-2025
Xinqiao Hospital
2025
Chongqing Municipal Health Commission
2024-2025
Xian Yang Central Hospital
2025
Shaanxi Provincial People's Hospital
2025
Shanxi Medical University
2025
International Peace Maternity & Child Health Hospital
2025
How cell-to-cell copy number alterations that underpin genomic instability
The assessment of nutritional status and the quality life in patients with gastric cancer has become one important goals current clinical treatment. purpose this study was to assess hospitalized by using patient-generated subjective global (PG-SGA) analyze influence on patients' (QOL). We reviewed pathological diagnosis for 2322 PG-SGA their collected data symptoms, anthropometric parameters (height, weight, body mass index (BMI), mid-arm circumference (MAC), triceps skin-fold thickness...
Abstract Background Handgrip strength (HGS) is associated with poor clinical outcomes, including all‐cause, non‐cardiovascular, and cardiovascular mortalities. The published cut‐off points for HGS are mostly based on community populations from Western countries, lacking information cancer patients China. objective of this study was to establish sex‐specific Chinese investigate the effect low mortality. Methods We did a retrospective cohort who were diagnosed malignant June 2012 December...
Although systemic inflammation is an important feature of the cancer cachexia, studies on association between and prognostic cachexia are limited. The objective this study to evaluate whether neutrophil-to-lymphocyte ratio (NLR) associated with outcome quality life for patients investigated any interaction NLR clinical parameters.This a multicentre cohort 2612 suffering from diagnosed June 2012 December 2019. main parameters measured were overall survival (OS) time all-cause mortality....
Abstract Background Malnutrition is prevalent in lung cancer (LC) patients, yet there are no globally accepted criteria for diagnosing malnutrition. Recently, the Global Leadership Initiative on (GLIM) were proposed. However, role of these prospective LC cohorts remains unclear. Methods We performed a multicenter, observational cohort study including 1219 patients. Different anthropometric measures compared assessment reduced muscle mass (RMM) GLIM criteria. Least absolute shrinkage and...
There are several approaches that can be used for the pre-treatment identification of malnutrition in oncology populations including Patient-Generated Subjective Global Assessment (PG-SGA), 2015 consensus statement by European Society Clinical Nutrition and Metabolism (ESPEN 2015) Leadership Initiative on Malnutrition (GLIM).
Examining the analytical worth of preoperative hemoglobin, albumin, lymphocyte, platelet (HALP) score and lymphocyte-to-monocyte ratio (LMR) within diseased persons having non-small cell lung cancer (NSCLC) after radical surgery.Clinical data concerning 238 with NSCLC who underwent resection Nantong Cancer Hospital between January 2009 October 2015 had been looking back studied. ROC curve employed in regulating optimal critical HALP LMR that 48.00 6.30 singly. A 5-year amplification observed...
The role of statin therapy in the development kidney disease patients with type 2 diabetes mellitus (DM) remains uncertain. We aimed to determine relationships between initiation and outcomes DM.
Background The exploration of genetic signatures within the ovarian cancer (OC) tumor microenvironment (TME) remains limited. M2-like tumor-associated macrophages (M2-like TAMs) are pivotal in OC progression and therapy. This study aims to establish a novel prognostic signature identify TAM-related biomarkers using RNAseq-based transcriptome analysis. Methods Prognostic genes were identified through univariate Cox regression, consensus clustering, LASSO regression. Immune landscape analysis...
Malnutrition is a problem affecting tumor patients greatly. This study aims to investigate whether demographic characteristics are related the malnutrition of cancer patients. Twenty-three thousand nine hundred and four (23,904) with 16 common malignant tumors were enrolled in study. Patient Generated Subjective Global Assessment (PG-SGA) was used as screening tool assess nutritional risk analysis variance compare PG-SGA scores Correlations between evaluated by correlation analysis. We...
The newly proposed Global Leadership Initiative on Malnutrition (GLIM) framework is promising to gain global acceptance for diagnosing malnutrition. However, the role of machine learning in facilitating its application clinical practice remains largely unknown.We performed a multicenter, observational cohort study including 3998 patients with cancer. Baseline malnutrition was defined using GLIM criteria, and population randomly divided into derivation group (n = 2998) validation 1000). A...
MDiverse indicators have been used to represent adipose tissue, while the relationship between body mass and prognosis of patients with cancer remains controversial. In this study, we aimed explore optimal composition that fat predict risk cancer-related mortality. We conducted a population-based multicenter prospective cohort study initial February 2012 September 2020. Clinical information, indicators, hematologic test results, follow-up data were collected. Body analyzed using principal...
The concept of possible sarcopenia (PS) was recently introduced to enable timely intervention in settings without the technologies required make a full diagnosis sarcopenia. This study aimed investigate association between PS and all-cause mortality patients with solid cancer. Retrospective observational study. 13,736 16 types cancer who were ≥18 years old. presence both low calf circumference (men <34 cm or women <33 cm) handgrip strength <28 kg <18 kg) considered indicate PS. Harrell's...
Many peptide hormones are synthesized as larger precursors which undergo endoproteolytic cleavage at paired basic residues to generate a bioactive molecule. Morphological evidence from several laboratories has implicated either the TGN or immature secretory granules site of prohormone cleavage. To identify where is initiated, we have used retrovirally infected rat anterior pituitary GH3 cells express high levels prosomatostatin (proSRIF) (Stoller, T. J., and D. Shields. J. Cell Biol. 1988....