A5100420320- Birth, Development, and Health
- Immune cells in cancer
- Neonatal and fetal brain pathology
- Liver Disease and Transplantation
- Childhood Cancer Survivors' Quality of Life
- Cerebrovascular and Carotid Artery Diseases
- Prenatal Screening and Diagnostics
- Polyomavirus and related diseases
- Hematopoietic Stem Cell Transplantation
- Medical and Biological Ozone Research
- Electrolyte and hormonal disorders
- Inflammatory mediators and NSAID effects
- Renal and related cancers
- Biomedical Research and Pathophysiology
- Epigenetics and DNA Methylation
- Neuroscience of respiration and sleep
- Land Use and Ecosystem Services
- Renal cell carcinoma treatment
- Intracranial Aneurysms: Treatment and Complications
- Bacterial Infections and Vaccines
- Neonatal Respiratory Health Research
- Nausea and vomiting management
- Gestational Trophoblastic Disease Studies
- Cardiac tumors and thrombi
- Neonatal Health and Biochemistry
International Peace Maternity & Child Health Hospital
2025
Shanghai Jiao Tong University
2025
Sichuan Normal University
2024
Second Affiliated Hospital of Xi'an Jiaotong University
2017-2023
First Affiliated Hospital of Gannan Medical University
2023
Tianjin People's Hospital
2012-2022
First Affiliated Hospital of Henan University
2022
Institute of Hematology & Blood Diseases Hospital
2022
Academy of Medical Sciences
2022
Chinese Academy of Medical Sciences & Peking Union Medical College
2019-2022
Background The exploration of genetic signatures within the ovarian cancer (OC) tumor microenvironment (TME) remains limited. M2-like tumor-associated macrophages (M2-like TAMs) are pivotal in OC progression and therapy. This study aims to establish a novel prognostic signature identify TAM-related biomarkers using RNAseq-based transcriptome analysis. Methods Prognostic genes were identified through univariate Cox regression, consensus clustering, LASSO regression. Immune landscape analysis...
Previous related studies have mainly focused on renal cell carcinoma (RCC) with venous tumor thrombus, specifically inferior vena cava thrombus vein (RVTT). However, only a few postoperative long-term survival of RCC patients exclusively RVTT. Our aim was to investigate the independent prognostic factors for locally advanced RVTT in China.Patients were enrolled study from January 2000 December 2015. All underwent radical nephrectomy. Survival analysis estimated using Kaplan-Meier....
Background The current study aims to detect the expression of C1q tumor necrosis factor related protein 3 (CTRP3) and CTRP9 in serum patients with gestational diabetes mellitus (GDM), so as provide basis for prevention treatment GDM. Methods A total 129 pregnant women GDM were selected, 130 normal glucose metabolism selected control group. levels CTRP3 detected by enzyme-linked immunosorbent assay (ELISA). Pearson's correlation was used compare between level clinical indicators. ROC analysis...
Liver fibrosis is a global health problem caused by number of diseases related to liver damage. 6-Shogaol biologically active substance derived from the rhizome Zingiber officinale Roscoe with anti-tumor, anti-inflammatory, and antioxidant properties. To explore effects on fibrosis, we used mouse model condition in which mice were injected intraperitoneally carbon tetrachloride (CCl4) at dose 2 mL/kg three times per week for period 4 weeks. was administered orally two different doses (5...
It has been well-documented that haplo-identical hematopoietic stem cell transplantation (HID-HSCT) can provide outcomes comparable to conventional matched sibling donor (MSD) HSCT, however, little is known about the effects on quality of life (QoL) in long-term survivors. This study investigate differences longitudinal performance QoL between HID and MSD HSCT using a comprehensive assessment system.
Non-invasive prenatal testing (NIPT) using cell-free DNA has been widely used for screening to detect the common fetal aneuploidies (such as trisomy 21, 18, and 13). NIPT shown be highly sensitive specific in previous studies, but false positives (FPs) negatives (FNs) occur. Although prevalence of FN results Down syndrome is rare, impact on families society significant.This article described two cases foetuses that tested "negative" 21 by technology semiconductor sequencing platform....
The biochemical markers of rat under low oxygen concentration, including brain water level, lactic acid, necrosis and Na+-K+-ATPase, was detected to analyze the hypoxia-induced damage, mechanism injury. Histopathological alteration in tissue induced by hypoxia were investigated through hematoxylin eosin stain (HE). Hypoxia factor-1a (HIF-1a) expression level carried out using immunohistochemistry. Lactic acid positively correlated with hypoxia, while concentration-dependent decrease total...
To evaluate the therapeutic effect of Saccharomyces boulardii supplementation on jaundice in premature infants undergoing phototherapy.In this article, authors reviewed 100 hospitalized jaundiced under 35 weeks gestational age. All were assigned to a control group (n = 45) and treatment 55) randomly. The received S. by phototherapy only treated phototherapy. total serum bilirubin levels detected before at end phototherapy, transcutaneous measured 1st, 4th, 8th 15th day treatment. duration...
ObjectivesOne-lung ventilation (OLV) for children under the age of two years is difficult. The authors hypothesize that a combination supraglottic airway (SGA) device and intraluminal placement bronchial blocker (BB) may provide an appropriate choice.DesignA prospective method-comparison study.SettingSecond Affiliated Hospital Xi'an Jiaotong University, China.Participants120 patients undergoing thoracoscopic surgery with OLV.InterventionsParticipants were randomly assigned to receive BB SGA...
Abstract Background: Spent culture medium (SCM) as a source of DNA for preimplantation genetic tests aneuploidy (PGT-A) has been widely discussed. Methods: Seventy-five blastocysts donated research provided unique possibility in which multiple specimens, including trophectoderm (TE) biopsy, SCM, and paired corresponding whole blastocyst (WB) specimens from the same source, could be utilized purpose this preclinical validation. Results: To conduct validation ploidy concordance assessment, we...
Chronic limb-threatening ischemia (CLTI) affects millions of people and causes health care burden around the globe. Global Limb Anatomic Staging System (GLASS) was proposed as a new anatomic system for integrating complexity threatened limb.We retrospectively classified computed tomography angiography images limbs into GLASS stages between January 2018 April 2020. Comorbidities, limb treatments, outcomes including amputation-free survival (AFS), reintervention mortality were compared...
Objective To investigate the influence of intracranial infection in incidence neonatal with epilepsy. Methods From May 2012 to 2015, 80 epilepsy were selected, and they divided into infected group non-infected according infection, 40 cases each group. The children given anti-seizure treatment, while therapy combined anti-infective therapy, then seizure frequency mean onset time, improvement EEG, risk factors two groups statistically analyzed. Results The seizures was...
Objective To explore the magnetic resonance angiography (MRA),digital subtraction (DSA) imaging characteristics of blood stream related aneurysms associated with Moyamoya disease and its treatment method.Methods Retrospective analysis was carried out on clinical data 6 patients to disease,admitted our hospital from January 2000 September 2012.Results Among patients,3 had ischemic cerebrovascular un-ruptured aneurysm; 2 3 ruptured aneurysm manifested as subarachnoid hemorrhage 1 in basal...
Objective To verify the validity of standard air cushion inflation method, and to explore relationship between patients' body mass index (BMI) optimal pressure. Methods A total 90 orthopedic patients who were treated in Liangxiang Hospital Fangshan District Beijing from June 2017 March 2018 randomly divided into experimental group control group, with 45 cases each group. The used bed routinely according experience nurses, while observation method previous research. Comparing skin...
Abstract Background: It has been well-documented that haplo-identical hematopoietic stem cell transplantation (HID-HSCT) can provide outcomes comparable to conventional matched sibling donor (MSD) HSCT, however, little is known about the effects on quality of life (QoL) in long-term survivors. This study investigate differences longitudinal recovery QoL between HID and MSD HSCT using a comprehensive assessment system. Methods: prospective enrolled consecutive patients who had received...