A5100352552- Plant Physiology and Cultivation Studies
- Plant Stress Responses and Tolerance
- Plant nutrient uptake and metabolism
- Photosynthetic Processes and Mechanisms
- Plant Disease Management Techniques
- Plant Reproductive Biology
- Enhanced Oil Recovery Techniques
- Plant Pathogens and Fungal Diseases
- Peanut Plant Research Studies
- GABA and Rice Research
- Nematode management and characterization studies
- Soybean genetics and cultivation
- Inflammatory Bowel Disease
- Plant Micronutrient Interactions and Effects
- Extracellular vesicles in disease
- Soil Carbon and Nitrogen Dynamics
- Plant Virus Research Studies
- Spectroscopy and Chemometric Analyses
- Genomics and Phylogenetic Studies
- Light effects on plants
- Plant Molecular Biology Research
- Polymer-Based Agricultural Enhancements
- Genetic diversity and population structure
- Microscopic Colitis
- Cancer-related molecular mechanisms research
Southern Medical University
2025
Shenyang Agricultural University
2015-2024
Sanya University
2024
Harbin Institute of Technology
2024
Shanxi Agricultural University
2024
Ministry of Agriculture and Rural Affairs
2020-2024
The University of Western Australia
2019-2024
Second Institute of Oceanography
2022-2024
Ministry of Natural Resources
2022-2024
Tianjin Medical University General Hospital
2024
How cell-to-cell copy number alterations that underpin genomic instability
Ferroptosis is a newly discovered form of cell death that featured in wide range diseases. Exosome therapy promising therapeutic option has attracted much attention due to its low immunogenicity, toxicity, and ability penetrate biological barriers. In addition, emerging evidence indicates exosomes possess the modulate progression diverse diseases by regulating ferroptosis damaged cells. Hence, mechanism which cell-derived noncellular-derived target different through system Xc
Breast cancer (BC) is a significant cause of cancer-related deaths among women worldwide. Hypoxia, common feature solid tumor, associated with drug resistance and poor prognosis in BC. In this study, we present strategy to overcome hypoxia-induced chemotherapy tolerance Specifically, synthesized hollow gold (Au)-platinum (Pt) bimetallic nanoshell for the first time, which acted as delivery system (DDS) doxorubicin (DOX). The photothermal effect, induced by surface plasmon resonance (SPR)...
Peroxisomes are components of virtually all eukaryotic cells. While much is known about peroxisomal matrix protein import, our understanding how membrane proteins (PMPs) targeted and inserted into the peroxisome extremely limited. Here, we show that PEX19 binds a broad spectrum PMPs, displays saturable PMP binding, interacts with regions PMPs required for their targeting to peroxisomes. Furthermore, mislocalization nucleus leads nuclear accumulation newly synthesized PMPs. At steady state,...
Actinidia chinensis is an important economic plant belonging to the basal lineage of asterids. Availability a complete chloroplast genome sequence crucial understanding phylogenetic relationships among major lineages angiosperms and facilitates kiwifruit genetic improvement. We report here nucleotide sequences genomes for A. var deliciosa obtained through de novo assembly Illumina paired-end reads produced by total DNA sequencing. The size ranges from 155,446 157,557 bp, with inverted repeat...
This paper studied the strengthening effects of silica nanoparticles on polyacrylamide (PAM)/hydroquinone (HQ)–hexamethylenetetramine (HMTA) composite gel. Pure PAM/HQ–HMTA gel and gels containing up to 0.3 wt % were prepared at 110 °C. Influences gelation performances systematically evaluated. By addition nanoparticles, time became shorter strength was improved observably. Rheological measurements showed that enhanced both elasticity viscosity significantly. Thermal stability by...
Recurring epidemics of kiwifruit (Actinidia spp.) bleeding canker disease are caused by Pseudomonas syringae pv. actinidiae (Psa). In order to strengthen understanding population structure, phylogeography, and evolutionary dynamics, we isolated from cultivated wild across six provinces in China. Based on the analysis 80 sequenced Psa genomes, show that China is origin pandemic lineage but strain diversity confined just a single clade. contrast, Korea Japan harbor strains multiple clades....
Background Diabetic nephropathy (DN) is one of the most common diabetic complications, which has become primary cause end-stage renal disease (ESRD) globally. Macrophage infiltration been proven vital in occurrence and development DN. This study was designed to investigate hub genes involved macrophage-mediated inflammation DN via bioinformatics analysis experimental validation. Methods Gene microarray datasets were obtained from Expression Omnibus (GEO) public website. Integrating...
Tubular epithelial cells (TECs) play critical roles in the development of diabetic nephropathy (DN), and can activate macrophages through secretion exosomes. However, mechanism(s) TEC-exosomes macrophage activation under DN remains unknown. By mass spectrometry, 1,644 differentially expressed proteins, especially Dll4, were detected urine exosomes patients compared with controls, which was confirmed by western blot assay. Elevated Epsin1 Dll4/N1ICD expression observed kidney tissues both...
In humans, defects in peroxisome biogenesis are the cause of lethal diseases typified by Zellweger syndrome. Here, we show that inactivating mutations human PEX3 syndrome, abrogate membrane synthesis, and result reduced abundance peroxisomal proteins (PMPs) and/or mislocalization PMPs to mitochondria. Previous studies have suggested may traffic through ER en route peroxisome, COPI inhibitor, brefeldin A, leads accumulation ER, overexpression alters morphology ER. However, were unable detect...
Kiwifruit (Actinidia chinensis Planchon) is an important specialty fruit crop that suffers from narrow genetic diversity stemming recent global commercialization and limited cultivar improvement. Here, we present high-density RAD-seq-based maps using interspecific F1 cross between Actinidia rufa 'MT570001' A. 'Guihai No4'. The (maternal) map consists of 2,426 single-nucleotide polymorphism (SNP) markers with a total length 2,651 cM in 29 linkage groups (LGs) corresponding to the chromosomes....
Peanut (Arachis hypogaea L.) is a globally important oil crop, which often experiences poor growth and seedling necrosis under low nocturnal temperatures (LNT). This study assessed the effects of supplementary calcium (Ca2+) calmodulin inhibitor on peanut photosynthetic characteristics plants exposed to LNT, followed by recovery at higher temperature. We monitored key parameters in climate-controlled chamber pots containing soil. LNT reduced dry matter accumulation, enhanced leaf...
Abstract Adjustments in root biomass allocation, morphology, carboxylate exudation and mycorrhizal symbiosis are well‐known strategies for plants to cope with phosphorus (P) deficiency. Large genotypic variation these functional traits has been demonstrated within numerous species. Yet, whether coordinated differently among genotypes of a species enhance P acquisition remains unknown. We characterized 11 associated 20 chickpea contrasting amounts rhizosheath carboxylates, grown glasshouse...
Mitochondrial quality control (MQC) plays a critical role in the progression of tubulointerstitial injury diabetic kidney disease (DKD). The mitochondrial unfolded protein response (UPRmt), which is an important MQC process, activated to maintain homeostasis stress. Activating transcription factor 5 (ATF5) mammalian UPRmt via mitochondria-nuclear translocation. However, ATF5 and tubular under DKD conditions unknown.ATF5 UPRmt-related proteins including heat shock 60 (HSP60) Lon peptidase 1...
Myricaria laxiflora is restricted to the riverbanks of Yangtze River valley and will be completely lost owing construction Three Gorges Dam. Genetic diversity structure nine natural one ex situ populations were investigated using amplified fragment length polymorphisms (AFLPs). A moderate level gene was found in populations, while population had highest. The F statistics calculated by different approaches consistently revealed a high genetic differentiation among contributing >45% total...
Abstract An outbreak of kiwifruit bacterial canker disease caused by Pseudomonas syringae pv. actinidiae (Psa) beginning in 2008 disaster to the industry. However mechanisms interaction between and Psa are unknown. Long noncoding RNAs (lncRNAs) known regulate many biological processes, but comprehensive repertoires lncRNAs their effects on Here, based in-depth transcriptomic analysis four materials at three stages infection with Psa, we identified 14,845 transcripts from 12,280 loci as...
The coordination/trade-off among below-ground strategies for phosphorus (P) acquisition, including root morphology, carboxylate exudation and colonisation by arbuscular mycorrhizal fungi (AMF), is not well understood. This the first study investigating relationships between nodulation, carboxylates an indigenous community of AMF under varying P levels source. Two chickpea genotypes with contrasting amounts rhizosheath were grown in pots at six (from 0 to 160 μg g-1 ) as KH2 PO4 (KP, highly...
Abstract Lung cancer is a widespread malignancy with high death rate and disorder of lipid metabolism. Lysophosphatidylcholine (lysoPC) has anti‐tumour effects, although the underlying mechanism not entirely known. The purpose this study aims at defining changes in lysoPC lung patients, effects on cells molecular mechanisms. cell sensitivity to was evaluated decisive roles long‐chain acyl‐coenzyme A synthase 5 (ACSL5) regulation were defined by comprehensively evaluating transcriptomic...