- Pregnancy and preeclampsia studies
- Maternal and fetal healthcare
- Maternal and Perinatal Health Interventions
- Ectopic Pregnancy Diagnosis and Management
- Birth, Development, and Health
- Gestational Diabetes Research and Management
- Immune Cell Function and Interaction
- Cancer-related gene regulation
- Cancer-related molecular mechanisms research
- Pregnancy and Medication Impact
- MicroRNA in disease regulation
- CAR-T cell therapy research
- Pregnancy-related medical research
- Epigenetics and DNA Methylation
- RNA modifications and cancer
- Kruppel-like factors research
- RNA Interference and Gene Delivery
- Biomarkers in Disease Mechanisms
- Assisted Reproductive Technology and Twin Pregnancy
- Cancer Risks and Factors
- Cardiovascular Issues in Pregnancy
- Cancer Immunotherapy and Biomarkers
- Gestational Trophoblastic Disease Studies
- Uterine Myomas and Treatments
- Cancer, Hypoxia, and Metabolism
Yuxian People's Hospital
2024-2025
First Affiliated Hospital of Zhengzhou University
2015-2024
Xinqiao Hospital
2023-2024
Army Medical University
2021-2024
Peking University
2018-2020
Peking University First Hospital
2018-2020
Zhengzhou University
2010
To explore the efficacy and safety of prophylactic temporary balloon occlusion infrarenal abdominal aorta during caesarean for management patients with placenta praevia accreta. Two hundred sixty-eight cases accreta from January 2012 to June 2015 were retrospectively reviewed. Group A included two thirty who underwent followed by section. B thirty-eight without endovascular intervention. The parameters including operating room time, estimated blood loss, transfusion volume, PT (prothrombin...
Abstract Growing evidence has shown that long noncoding RNAs (lncRNAs) play crucial roles in cervical cancer. Dy000sregulation of lncRNA SOX21 antisense RNA 1 (SOX21‐AS1) been reported several tumors. However, its expression pattern and potential biological function cancer (CC) have not investigated. In this study, we first SOX21‐AS1 was significantly upregulated both CC tissues cell lines. High found to be correlated with Federation Gynecology Obstetrics (FIGO) stage, lymph node metastasis...
BackgroundLow-dose aspirin has been the most widely studied preventive drug for preeclampsia. However, guidelines differ considerably from country to regarding prophylactic use of There is limited evidence large trials determine effect 100 mg preeclampsia screening in women with high-risk pregnancies, based on maternal risk factors, and guide low-dose prevention China.ObjectiveThe Low-Dose Aspirin Prevention Preeclampsia China study was designed evaluate preventing among pregnant screened...
To compare the efficacy of temporary abdominal aortic occlusion with internal iliac artery for management placenta accreta.105 patients accreta were selected treatment (n = 57, group A) or bilateral 48, B). Temporary and balloon occlusions performed during caesarean sections. Data regarding clinical success, blood loss, transfusion, insertion time, fluoroscopy foetal radiation dose, complications collected.Temporary technically successful in all patients. The amount loss (P < 0.001),...
Abstract S-palmitoylation is essential for cancer development via regulating protein stability, function and subcellular location, yet the roles plays in diffuse large B-cell lymphoma (DLBCL) progression remain enigmatic. In this study, we uncovered a novel of palmitoyltransferase ZDHHC21 as tumor suppressor DLBCL identified key regulator fatty acid synthetase (FASN) first time. Specifically, was downregulated DLBCL, its expression level associated with clinical prognosis patients DLBCL....
To investigate the relationship between first trimester subchorionic hematoma (SCH) and fetal growth restriction (FGR), to develop a nomogram for predicting risk of FGR in patients with SCH. We conducted retrospective cohort study from January 2021 December 2021, involving singleton pregnancies that received routine prenatal care since at our hospital. excluded loss before 20 weeks ultimately included 1,055 individuals study, dividing them into two groups based on whether they were diagnosed...
Abstract Maternal diet is an important potential factor associated with the risk of preeclampsia. However, it unclear whether adherence to a Dietary Approaches Stop Hypertension (DASH)-style can reduce development To examine association, we conducted hospital-based case-control study at First Affiliated Hospital Zhengzhou University, China. A total 449 cases preeclampsia and controls were studied. information was collected using validated food frequency questionnaire (FFQ). DASH scores...
Objective: The objective of this study is to identify the maternal and neonatal outcomes in women with placenta increta or percreta China.Materials methods: We retrospectively analyzed 2219 cases from 20 tertiary care centers China between January 2011 December 2015. All were diagnosed percreta, based on either intraoperative findings histopathological findings.Results: incidence progressively increased 0.18% 0.78% Compared increta, was strongly related serious adverse outcomes: postpartum...
Background Placenta accreta spectrum (PAS) refers to a of conditions characterized by the abnormal adherence placenta implantation site and has been challenge due risk postpartum hemorrhage, peripartum hysterectomy maternal mortality. Despite sonographic findings, no consensus on prenatal evaluation PAS established yet. We are aiming establish scoring system increase accuracy prediction severity, especially differentiate percreta increta.Methods conducted retrospective study collected 2,219...
Abstract The association between dietary fat intake during pregnancy and the risk of developing preeclampsia has been examined in many epidemiological studies, but results remain inconsistent. aim this study was to clarify pregnant Chinese women. After conducting 1:1 matching, 440 pairs consisting women with hospital-based, healthy matched by gestational week (± 1 week) age 3 years) were recruited. A 79-item semi-quantitative food frequency questionnaire administered face-to-face interviews...
We aimed to evaluate our experience with the application of uterine wall local resection and reconstruction preserve uterus in patients morbidly adherent placenta. In a retrospective study, data from placenta who delivered by cesarean section between January 1, 2013 May 31, 2016 were analyzed. Prophylactic abdominal aorta balloon occlusion tourniquet used prevent massive hemorrhage all 62 cases, followed uterus. The quantity estimated blood loss (EBL), operation time, complications...
To identify the 24-h proteinuria value with quantitative analysis and how it correlates severity of preeclampsia subsequent adverse maternal outcomes in Chinese population.Eleven hospitals 10 provinces across China were chosen, which 1,738 pregnant women complicated by hypertensive disorders pregnancy (HDP) records 24 h enrolled. They allocated into four groups: patients maximal quantified < 0.3 g/24 (Group 1, n = 328); ≥ 2.0 2, 638); 5.0 3, 353); 4, 419). Logistic regression conducted to...
Massive bleeding is the main concern for management of placenta percreta (PP). Intra-abdominal aortic balloon occlusion (IABO) one method pelvic devascularization, but efficacy IABO uncertain. This study aims to investigate outcomes in PP patients.We retrospectively reviewed clinical data cases from six tertiary centers China between January 2011 and December 2015. with/without use were analyzed. Propensity score matching analysis was performed reduce effect selection bias. Postpartum...
To explore the association between inter-pregnancy intervals and placenta previa accreta spectrum among women who had prior cesarean deliveries with respect to maternal age at first delivery.This retrospective study included clinical data from 9981 singleton pregnant a history of delivery 11 public tertiary hospitals in seven provinces China January 2017 December 2017. The population was divided into four groups (<2, 2-5, 5-10, ≥10 years interval) according interval. rate compared,...
Previous studies on the relationship between dietary minerals and preeclampsia (PE) have given inconsistent results. The aim of this study was to further clarify intake PE in Chinese pregnant women. In study, 440 pairs hospital-based preeclamptic healthy women were matched 1:1. Dietary obtained through a 78-item semi-quantitative food frequency questionnaire. Multivariate conditional logistic regression used estimate odds ratios (ORs) 95% confidence intervals (CIs). Restricted cubic splines...
Abstract Background To determine the effects of maternal age at first cesarean on complications and adverse outcomes pregnancy with second cesarean. Methods This was a multicenter, historical, cross-sectional cohort study involving singleton pregnancies ≥28 gestational weeks, history 1 delivery, who underwent between January December 2017 11 public tertiary hospitals in 7 provinces China. We analyzed using multivariate logistic regression analysis. Results The consisted 10,206 pregnancies....
Objective To compare conservative management and cesarean hysterectomy in patients with placenta increta or percreta.Materials methods In this multicenter retrospective study, we recorded data on 2219 percreta from 20 tertiary care centers China 1 January 2011 to 31 December 2015. Propensity score analysis was used control for baseline characteristics. We divided into (C) (H) groups. The primary outcome operative/postoperative maternal morbidity; secondary outcomes were maternal–neonatal...