A5076716729- Inflammatory Bowel Disease
- Dermatology and Skin Diseases
- Epigenetics and DNA Methylation
- Ferroptosis and cancer prognosis
- Obesity, Physical Activity, Diet
- Allergic Rhinitis and Sensitization
- Microscopic Colitis
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Treatment and Management
- Food Allergy and Anaphylaxis Research
- MicroRNA in disease regulation
- Cancer Genomics and Diagnostics
- TGF-β signaling in diseases
- Eosinophilic Esophagitis
- Bone health and treatments
- Liver physiology and pathology
- Health and Lifestyle Studies
- Spinal Cord Injury Research
- Venous Thromboembolism Diagnosis and Management
- Complementary and Alternative Medicine Studies
- Cancer Risks and Factors
- Circular RNAs in diseases
- Polyomavirus and related diseases
- Chronic Kidney Disease and Diabetes
- Peptidase Inhibition and Analysis
Huazhong University of Science and Technology
2011-2025
Tongji Hospital
2012-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
Guangdong Medical College
2025
Ministry of Education of the People's Republic of China
2024
National Health and Family Planning Commission
2024
Zhongshan People's Hospital
2024
Jinan University
2024
AbbVie (United States)
2019-2023
Brigham and Women's Hospital
2023
Current understanding of the associations between actual body weight status, perception, dissatisfaction, and control practices among low-income urban African American adolescents is limited. The knowledge can help direct future intervention efforts.Cross-sectional data including measured height self-reported status collected from 448 in four Chicago Public Schools were used.The prevalence overweight obesity (BMI > or = 85th percentile) was 39.8%, but only 27.2% considered themselves as...
Resistance to anoikis, cell death due matrix detachment, is acquired during tumor progression. The 14-3-3σ protein implicated in the development of chemo- and radiation resistance, indicating a poor prognosis multiple human cancers. However, its function anoikis resistance metastasis hepatocellular carcinoma (HCC) currently unknown. Methods: Protein expression levels were measured paired HCC normal tissue samples using western blot immunohistochemical (IHC) staining. Statistical analysis was...
<b><i>Background:</i></b> Renal tubulointerstitial fibrosis is the final common stage of renal failure. CD4+ T lymphocyte recruitment and activation after injury could be very important early event that mediates onset fibrogenesis. But role lymphocytes in controversial its cellular mechanism needs to further investigated. <b><i>Methods:</i></b> Biopsy specimens were from patients with minimal-change or IgA nephropathy. Mouse was induced by...
Primary sclerosing cholangitis (PSC) is a rare obliterative fibrotic condition of the bile ducts. We assessed PSC epidemiology and natural history within UK Clinical Practice Research Datalink (CPRD). Incidence were evaluated in retrospective cohort study using linkage CPRD, Hospital Episode Statistics, Office for National Statistics data. Data from age, sex, general practice-matched population controls provided context incident patients. Liver disease other than was defined as autoimmune...
To assess overweight and related risk factors among urban low socio-economic status (SES) African-American adolescents in an attempt to study the underlying causes of ethnicity gender disparities overweight.Cross-sectional data collected on anthropometric measures, diet, physical activity family characteristics from 498 students grades 5-7 four Chicago public schools were analysed for using stepwise regression analysis.Only 37.2% lived with two parents. Nearly 90% had a television (TV) their...
Abstract Background In USA, total shoulder arthroplasty (TSA) ranks amongst the top five surgeries that require hospitalization. As a result, healthcare system in USA could face considerable financial strain due to emergence of subsequent pulmonary problems. This study aimed conduct thorough examination prevalence, influential factors and medical importance complications, with emphasis on pneumonia, respiratory failure embolism (PE) following procedures USA. Methods The National Inpatient...
Immune checkpoint inhibitors (ICIs) have revolutionized systemic hepatocellular carcinoma (HCC) treatment. Nevertheless, numerous patients are refractory to ICIs therapy. It is currently unknown whether diet therapies such as short-term starvation (STS) combined with can be used treat HCC. This study aimed investigate STS could sensitize HCC tumors immunotherapy. was found attenuate tumor progression by inducing tumor-associated macrophages (TAMs) switch an antitumoral phenotype, enhancing...
Diabetes is an important global disease, associated with significant morbidity and increased risk of death due to chronic end-organ complications. The thiazolidinediones, used mainly as third-line agents in type 2 diabetes mellitus (T2DM), have been some safety concerns, such bladder cancer, bone fracture heterogeneous effects on cardiovascular events. This study aimed evaluate data pioglitazone for several outcomes examine them context each other well insulin, another treatment T2DM....
Real-world data on the epidemiology and economic burden of atopic dermatitis (AD) are limited. Here we describe AD using electronic healthcare from Israel. A retrospective study was performed Maccabi Healthcare Services database. incidence in 2008–2017 point prevalence (ADprev) 31 December 2017 were described diagnosis codes for overall patients, sex age subgroups. For ADprev, severity defined recently dispensed treatments AD. Annual resource utilization prevalent patients compared with...
Background Certain immune-mediated inflammatory diseases (IMIDs) may increase patients' risk for venous thromboembolisms (VTEs), yet how atopic dermatitis (AD) influences VTE remains unclear. Objective Describe incidence in patients with AD compared other IMIDs and unaffected, AD-matched controls. Methods This retrospective, observational, comparative cohort study used Optum® Clinformatics® United States claims data (2010–2019) of adults AD, rheumatoid arthritis (RA), Crohn's disease (CD),...
To assess incidence rates (IRs) of VTE in patients with rheumatoid arthritis (RA) on different DMARDs and DMARD switchers.Adults RA a between 2007 2017 were studied US claims database. Conventional synthetic (csDMARD) users, first biologic/targeted (b/tsDMARD) users b/tsDMARD switchers (from to another b/tsDMARD) followed for inpatient (pulmonary embolism (PE)/deep vein thrombosis (DVT)). Crude adjusted IR 95% CIs estimated. HRs estimated via Cox regression. risk was also evaluated by number...
ABCC1 belongs to the ATP-binding cassette (ABC) superfamily, which encompasses a total of 48 constituent members. has been shown be associated with growth, progression, and drug resistance various types cancer. However, impact on cancer immune infiltration pan-cancer prognosis rarely studied. Our comprehensive analysis unveiled elevated expression across cancers. overexpression consistently predicted unfavorable outcomes based TCGA data. Moreover, exhibited intricate associations diverse...
To rigorously evaluate the short-term and long-term effectiveness of Tuina (TN), alone in combination with physiotherapy (PT), for Chronic nonspecific low back pain (CNLBP) through a comprehensive, high-quality clinical trial.
Objectives:The objectives of this study were to assess and compare all-cause mortality rates between pioglitazone (PIO) insulin (INS).Research design:The population included 56,536 patients with type 2 diabetes aged ≥45 years who first-time users PIO or INS. Data from 1 May 2000 until 30 June 2010 the i3 InVision Mart database linked death records US Social Security Administration obtained in March 2012, approval Institutional Review Board full compliance Health Insurance Portability...
Progressive multifocal leukoencephalopathy is a serious condition linked to certain diseases and immunosuppressant therapies, including the α4 integrin antagonist natalizumab. No cases have been reported date with vedolizumab, selective of α4β7 expressed on gut-homing lymphocytes. This analysis aimed describe current future expected occurrence progressive vedolizumab use, were risk same as in other populations which this disease has studied. The number vedolizumab-associated was estimated up...