Aims: The purpose of this study was to provide micrographic evidences for the damaged membrane structure and intracellular change Escherichia coli strain 8099, induced by polyhexamethylene guanidine hydrochloride (PHMG). Methods Results: bactericidal effect PHMG on E. investigated based β‐galactosidase activity assay, fluorescein‐5‐isothiocyanate confocal laser scanning microscopy, field emission electron microscopy transmission microscopy. results revealed that a low dose (13 μg ml−1)...

The combination of transparency, antimicrobial activities, nonleaching component and green preparation for poly(vinyl alcohol) (PVA) films is importance practical applications in industry. However, until now it remains a challenge. Herein, facile PVA containing polyhexamethylene guanidine (PHMG) reported via solution casting method. Such show high transparency 91%, above 99.99% rates against Escherichia coli Staphylococcus aureus, characteristic PHMG due to the hydrogen-bond (H-bond)...

Fabrication of superhydrophobic surfaces based on PEW and SiO₂ though a vapor-induced method.

Abstract Background Gemcitabine is a cornerstone drug for the treatment of all stages pancreatic cancer and can prolong survival patients with cancer, but resistance to gemcitabine in hinders its efficacy. The overexpression Early growth response 1(EGR1) ductal adenocarcinoma as mechanism chemoresistance has not been explored. major mechanisms are related uptake, metabolism, action. One common causes tumor multidrug (MDR) chemotherapy cells that transporter proteins increase intracellular...

Abstract In order to protect the marine environment, traditional antifouling coatings such as tributyltin (TBT)‐based have been phased out. There is an urgent need develop environmentally friendly coatings. this work, antibacterial poly(hexamethylene guanidine) (PHMG) was introduced into polyurethane (PU) through chemical bond prepare a green coating (PU‐PHMG). The morphology, antimicrobial properties, mechanical properties and thermostability of PU‐PHMG films were investigated. rates...

Abstract More information regarding the bactericidal properties of polyhexamethylene guanidine hydrochloride (PHMG) against clinically important antibiotic‐resistant ESKAPE ( Enterococcus faecium , Staphylococcus aureus Klebsiella pneumoniae Acinetobacter baumannii Pseudomonas aeruginosa and Enterobacter species) pathogens needs to be provided for its uses in infection control. The PHMG chlorhexidine digluconate (CHG) were compared based on their minimum inhibitory concentrations (MICs),...

This study investigated the relationship between extensional rheological behaviors and foamability of polypropylenes (PPs). Both shear properties four types PPs with different molecular structures (linear PP, linear PP high-molecular component, long-chain-branched cross-linked PP) were tested by rheometers foamed batch process supercritical carbon dioxide as foam agent. It was found that when showed strain-hardening behavior at certain strain rates (on order 1 s −1 ), obtained foams had high...

ABSTRACT The thermal aging behavior of poly(3,3,3‐trifluoropropyl)methylsiloxane was investigated by gravimetric analysis and isothermal tests, the results indicated degradation mechanism II, oxidation scission side groups, played a more important role when temperature below 350 °C. addition ceria had significantly improved stability fluorosilicone rubber (FSR) inhibiting scission. Moreover, two types including laminar‐structure (LS‐CeO 2 ) nanoparticle (N‐CeO were prepared surface modified...

It is still crucial to improve the mechanical characteristics of polyvinyl alcohol (PVA) films without resorting chemical cross-linking. In this study, boric acid (BA) was used enhance PVA while maintaining their excellent transparency and biodegradability. The hydrogen bond interaction between BA resulted in a 70% increase tensile strength (from 48.5 82.1 MPa) 46% elongation at break 150 220%). To introduce antibacterial properties, polyhexamethylene guanidine hydrochloride (PHMG)...

Novel antimicrobial PVP-GP hydrogels were prepared by polycondensation of hexamethylenediamine and guanidine hydrochloride, followed cross-linking reaction using N-vinyl pyrrolidone (NVP) N,N'-methylene bisacrylamide (MBAm). The products characterized 1H NMR, FTIR, SEM, their performances for wound dressing applications also evaluated. Swelling study showed that the water absorptivity decreased as density increased either in or physiological saline solution. Both PVP possessed excellent...

Abstract Polyhexamethylene guanidine hydrochloride (PHMG) oligomer is attracting increasing attention for its highly efficient biocidal activity and nontoxicity. To make it bearing carbon‐to‐carbon double bonds enlarge application in production of antimicrobial materials via copolymerization, PHMG was modified reaction with glycidyl methacrylate (GMA). The influence parameters on the conversion rate GMA investigated using ultraviolet absorption spectroscopy. structures before after...

Biofouling is one of the major obstacles in application poly(vinylidene fluoride) (PVDF) membrane water and wastewater treatment. Developing antimicrobial PVDF could kill attached microbe initial stage, thus theoretically inhibiting formation biofilm delaying occurrence biofouling. However, leaching component deterioration properties remain a concern. In this work, an (PVDF-g-AGE-PHMG) was developed by chemical bonding with poly(hexamethylene guanidine hydrochloride) (PHMG). The obtained...