Seyed Parsa Eftekhar

ORCID: 0000-0002-1175-4380
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Viral Infections and Immunology Research
  • Diet, Metabolism, and Disease
  • Stress Responses and Cortisol
  • Tryptophan and brain disorders
  • Cardiac electrophysiology and arrhythmias
  • Liver Disease Diagnosis and Treatment
  • Cardiovascular Function and Risk Factors
  • Bacterial Infections and Vaccines
  • Circular RNAs in diseases
  • Anesthesia and Sedative Agents
  • Antifungal resistance and susceptibility
  • Vitamin D Research Studies
  • Sepsis Diagnosis and Treatment
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Colorectal Cancer Treatments and Studies
  • Chemotherapy-induced organ toxicity mitigation
  • Cancer-related molecular mechanisms research
  • Venous Thromboembolism Diagnosis and Management
  • Long-Term Effects of COVID-19
  • Inflammatory mediators and NSAID effects
  • Adipose Tissue and Metabolism
  • Pediatric Pain Management Techniques
  • Nigella sativa pharmacological applications

Tehran University of Medical Sciences
2025

Babol University of Medical Sciences
2020-2024

Aja University of Medical Sciences
2024

Universal Scientific Education and Research Network
2021

Percutaneous valve implantation or surgical replacement with mechanical biological valves are standard therapies for severe valvular heart diseases. Prosthetic thrombosis, though rare, is a serious complication, particularly prostheses. This study aimed to investigate the predictive value of platelet volume parameters, including mean (MPV), distribution width (PDW), and platelet-large cell ratio (P-LCR), thrombosis risk in patients undergoing therapy. A retrospective cross-sectional was...

10.1177/10760296241311268 article EN cc-by-nc Clinical and Applied Thrombosis/Hemostasis 2025-01-01

Hydroxychloroquine with or without azithromycin was one of the common therapies at beginning COVID-19 pandemic. They can prolong QT interval, cause torsade de pointes, and lead to sudden cardiac death. We aimed assess interval prolongation its risk factors in patients who received hydroxychloroquine azithromycin.

10.1155/2021/6683098 article EN cc-by Cardiovascular Therapeutics 2021-02-27

Thymoquinone (TQ) is one of the components extracted from Nigella sativa seeds and has antioxidant, anti-inflammatory, anticancer effects. We evaluated effect TQ on 5-fluorouracil (5-FU) pharmacokinetics (PK) in vivo vitro human colorectal cancer cell line. Ten Adult male Wistar rats were assigned to two groups. treated group received intraperitoneal once daily for 14 consecutive days (5 mg/kg). Both groups 5-FU (50 mg/kg) day 15 blood samples collected retro-orbital plexus. The parameters...

10.1177/09603271221145422 article EN Human & Experimental Toxicology 2022-01-01

Abstract This Study describes eleven patients positive for severe acute respiratory syndrome coronavirus 2. In our cases, females and younger developed more disease. contrast, improvement in left ventricular ejection fraction N‐terminal prohormone brain natriuretic peptide within the first week of treatment contributed to promising outcomes.

10.1002/ccr3.5236 article EN Clinical Case Reports 2021-12-01

Abstract We present a case of aspergillus brain abscess in 48‐year‐old woman with history kidney transplantation and no underlying central nervous system (CNS) disease. Follow‐up the patient for 4 years shows normal findings. Early diagnosis aggressive treatment could improve prognosis this fatal complication.

10.1002/ccr3.6169 article EN Clinical Case Reports 2022-08-01

Abstract Background Intravenous lidocaine has shown promise as an effective analgesic in various clinical settings, but its utility for pain management emergency departments, especially bone fractures, remains relatively understudied. Objective This study compared intravenous to pethidine femoral fracture management. Methods double-blind, randomized, controlled trial was conducted the department of AJA University Medical Sciences affiliated hospitals. Patients aged 18–70 years-old with and...

10.1186/s12871-024-02640-4 article EN cc-by BMC Anesthesiology 2024-07-23

Maintaining the proper fluid balance is a fundamental step in management of hospitalized patients. The current study evaluated impact negative on outcomes patients with confirmed COVID-19.

10.1155/2023/6957341 article EN cc-by Canadian Journal of Infectious Diseases and Medical Microbiology 2023-06-05

We described eleven patients positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The younger age and female gender seem to contribute poor outcomes possibly. Furthermore, the left ventricle ejection fraction pro-BNP improvement within first week of treatment might indicate a good prognosis.

10.22541/au.162757208.89784925/v2 preprint EN Authorea (Authorea) 2021-08-02

This study aimed to evaluate the impact of ketorolac on pharmacokinetics 5-FU and its effect efficacy 5-fluorouracil (5-FU) HT-29 cell line.Cell culture: line was treated with different concentrations 5-FU, ketorolac, combination for 24 48 hours. The viability (%) calculated by MTT assay. Animal study: rats were randomly divided into control pretreatment groups. group received physiological saline, whereas intraperitoneal (i.p.) injections a daily basis 14 days. On 15th day, both groups...

10.1155/2022/5267861 article EN cc-by Journal of Tropical Medicine 2022-09-21

Abstract Background Hydroxychloroquine with or without azithromycin was one of the common therapies at beginning COVID-19 pandemic. They can prolong QT interval, cause Torsade de pointes, and lead to sudden cardiac death. We aimed assess interval prolongation its risk factors in patients who received hydroxychloroquine azithromycin. Methods This a retrospective cohort study. 172 included, hospitalized hospitals Babol University Medical Sciences between March 5, 2020, April 3, 2020. Patients...

10.1101/2021.01.16.21249941 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2021-01-26

We described eleven patients positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The younger age and female gender seem to contribute poor outcomes possibly. Furthermore, the left ventricle ejection fraction pro-BNP improvement within first week of treatment might indicate a good prognosis.

10.22541/au.162757208.89784925/v1 preprint EN Authorea (Authorea) 2021-07-29
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