A5103152655- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Knee injuries and reconstruction techniques
- Pharmacological Effects of Natural Compounds
- Traditional Chinese Medicine Analysis
- Allergic Rhinitis and Sensitization
- Natural product bioactivities and synthesis
- Orthopedic Infections and Treatments
- Food Quality and Safety Studies
- Asthma and respiratory diseases
- Heme Oxygenase-1 and Carbon Monoxide
- Lower Extremity Biomechanics and Pathologies
- Ginseng Biological Effects and Applications
- Healthcare and Venom Research
- Traditional Chinese Medicine Studies
- Diverse Approaches in Healthcare and Education Studies
- Osteoarthritis Treatment and Mechanisms
- Phytochemistry and Biological Activities
- Immune Response and Inflammation
- Electrospun Nanofibers in Biomedical Applications
- Dyeing and Modifying Textile Fibers
- Genomics, phytochemicals, and oxidative stress
- Natural Fiber Reinforced Composites
- Hydrogels: synthesis, properties, applications
- Advanced Cellulose Research Studies
Korea Food Research Institute
2015-2024
The Graduate Center, CUNY
2024
Ulsan College
2023-2024
University of Ulsan
2023-2024
Asan Medical Center
2023-2024
Kangdong Sacred Heart Hospital
2023
Hallym University
2023
Yonsei University
2019-2023
Yonsei Sarang Hospital
2019-2023
Sookmyung Women's University
2023
The development of successful scaffolds for bone tissue engineering requires concurrent that combines different research fields. In previous studies, phenomenological computational models predicted the mechanical properties a scaffold in simple loading condition using mechano-regulation theory. Therefore, aim this study is to predict an optimum required cartilage regeneration three-dimensional knee joint developed from medical imaging and It was with optimal would result greater amounts...
Studies have shown that stem cells and their derivatives, including conditioned media (CM), inhibitory effects on skin pigmentation. However, evidence supporting the brightening effect of exosomes derived from is lacking. We studied antipigmentation in vitro efficacy vivo human adipose tissue-derived mesenchymal stem/stromal (ASC-exosomes). Exosomes were isolated CM ASCs using tangential flow filtration method. ASC-exosomes reduced intracellular melanin levels B16F10 melanoma regardless...
The fruit of Cornus officinalis Sieb. et Zucc. is commonly prescribed in Asian countries as a tonic formula. In this study, the hepatoprotective effect ethanolic extracts C. (ECO) was investigated mouse model acetaminophen- (APAP-) induced liver injury. Pretreatment mice with ECO (100, 250, and 500 mg/kg for 7 days) significantly prevented APAP (200 mg/kg) hepatic damage indicated by serum marker enzymes (AST, ALT, LDH). Parallel to these changes, treatment also APAP-induced oxidative stress...
The aim of this study was to improve the anti-inflammatory activities apigenin through co-treatment with resveratrol as a bioenhancer apigenin. RAW 264.7 cells pretreated hepatic metabolites formed by co-metabolism and (ARMs) in HepG2 were stimulated lipopolysaccharide (LPS). ARMs prominently inhibited (p < 0.05) production nitric oxide (NO), prostaglandin E2 (PGE2), interleukin (IL)-1β, IL-6 TNF-α. Otherwise no such activity observed alone (AMs). also effectively suppressed protein...
Abstract Background This study aimed to investigate the biomechanical effect on Takeuchi classification of lateral hinge fracture (LHF) after an opening wedge high tibial osteotomy (HTO). Methods We performed FE simulation for type I, II, and III in accordance with classification. The stresses bone plate, micromotion, forces ligaments were evaluated stress-shielding effect, plate stability, change, respectively, three different types LHF HTO without model (non-LHF) models. Results greatest...
Radical cystectomy with preoperative cisplatin-based neoadjuvant chemotherapy (NAC) is the standard care for muscle-invasive bladder cancers (MIBCs). However, complete response rate to this modality remains relatively low, and current clinicopathologic molecular classifications are inadequate predict NAC in patients MIBC. Here, we demonstrate that dysregulation of glutathione (GSH) pathway fundamental MIBC resistance. Comprehensive analysis multicohort transcriptomes reveals GSH metabolism...
The wear of tibial inserts in total knee arthroplasty (TKA) remains a major limitation longevity. However, tests are expensive and time-consuming. Computational prediction using finite-element (FE) model followed by validation through comparison with experimental data is effective for assessing new prosthetic designs or materials prior to functional testing surgical implementation. In this study, the kinematics, volumetric wear, depth made different (ultrahigh-molecular weight polyethylene...
Abstract Mentha haplocalyx Briq., a commonly used herb in traditional Oriental medicine, has variety of known pharmacological properties. However, neither the protective effects ethanol extract (MH) against inflammation airway an asthmatic model nor mechanisms involved, have previously been reported. In present study, ovalbumin (OVA)‐induced mouse allergic asthma was to investigate whether MH effective disease through regulation inflammation. The treatment significantly inhibited increases...