- Dialysis and Renal Disease Management
- Renal Transplantation Outcomes and Treatments
- Renal Diseases and Glomerulopathies
- Inflammasome and immune disorders
- Metabolism and Genetic Disorders
- Central Venous Catheters and Hemodialysis
- Muscle and Compartmental Disorders
- Organ Donation and Transplantation
- Genetic and Kidney Cyst Diseases
- Parathyroid Disorders and Treatments
- Hemoglobinopathies and Related Disorders
- Systemic Lupus Erythematosus Research
- Gout, Hyperuricemia, Uric Acid
- Genetic Syndromes and Imprinting
- Organ Transplantation Techniques and Outcomes
- Electrolyte and hormonal disorders
- Neurological and metabolic disorders
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Chronic Kidney Disease and Diabetes
- Folate and B Vitamins Research
- Neurological Complications and Syndromes
- Hepatitis B Virus Studies
- Transplantation: Methods and Outcomes
- Pharmacology and Obesity Treatment
- Pharmacological Effects and Toxicity Studies
Isparta University of Applied Sciences
2024
Akdeniz University
2015-2023
Akdeniz University Hospital
2019-2021
Antalya Eğitim ve Araştırma Hastanesi
2010-2016
Atatürk University
2000-2015
Ministry of Health
2013
Inonu University
2012
Erzurum Technical University
2010
Antalya IVF
2004
Izmir Tepecik Eğitim ve Araştırma Hastanesi
2003
HELLP syndrome, a syndrome of hemolysis, elevated liver enzymes and low platelets may occur in pregnancy with pre-eclampsia/eclampsia, its significant complication is acute renal failure (ARF).The aim study was to determine frequency outcome complicated by ARF.Thirty-nine patients pregnancy-related ARF were treated between Jan 1, 1989 1999. In these patients, the most frequent causes (n = 14; 36%), postpartum hemorrhage 10; 26%), pre-eclampsia/eclampsia 6;15%) abruptio placenta 4;10%). Seven...
Background. Adequate care of a hemodialysis patient requires constant attention to the need maintain vascular access (VA) patency. VA complications are main cause hospitalization in patients. The native arteriovenous fistula (NAVF), synthetic grafts (GAVF) and silastic cuffed central venous catheters (CVCs) used for permanent (PVA). CVCs primary method choice temporary access. But using this modality is increasing more PVA elderly patients when other not possible. aim study investigate...
In this study of 26 patients, clinical features diagnosed as urinary tuberculosis in our nephrology and urology clinics between 1993 2002 were investigated retrospectively. Fifteen patients (52%) male, mean age was 43.5 (18–71). Twenty percent the asymptomatic. Frequency-dysuria (46%), flank pain (33%), macroscopic hematuria (12%) presenting symptoms. Physical examination not diagnostically helpful most patients. Hematuria and/or pyuria detected 80% Eleven had positive urine cultures...
We aimed to determine the prevalence of sexual dysfunction and clarify relationship between depressive mood state, drugs, disease activities in patients with predialytic chronic kidney (CKD).In total, 150 CKD who had an estimated glomerular filtration rate 15-60 mL/min were included; 65 healthy controls selected. A detailed medical history was taken from individuals control patient groups by applying Golombok-Rust Inventory Sexual Satisfaction Hospital Anxiety Depression Scale.Sexual...
Objective There are various causes of halitosis, one which is chronic renal failure. The objective this study was to investigate halitosis levels in end-stage disease (ESRD) patients before and after peritoneal dialysis (PD) therapy. Methods 42 subjects with ESRD were included study. presence assessed using an organoleptic measurement compared blood urea nitrogen (BUN) salivary flow rates. Decayed, missing, filled teeth (DMFT) index Community Periodontal Index (CPI) calculated. All...
<i>Aim:</i> Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary disease. It accounts for 5–10% of patients with end-stage renal (ESRD). The aim this multicenter study was to investigate demographic and clinical characteristics ADPKD. <i>Methods:</i> 1,139 ADPKD who were followed up at 12 different centers recruited study. investigated gender, age, smoking history, educational status, existence hypertension, hematuria, urinary tract...
Omalizumab, a recombinant humanized monoclonal antibody to IgE, is recommended as new option for the treatment of severe persistent allergic asthma. The purpose this study assess effects omalizumab on life quality and its side in asthma patients.In study, we evaluated 19 patients who received therapy with 8 months. Omalizumab was administered every 2 weeks at doses between 150 375 mg. Symptoms severity reactions were recorded before after being omalizumab. IgE levels, mean platelet volume...
Objective: Von Willebrand factor (vWF) is a mediator that increases endotoxemic medium like in cirrhosis.In this study we evaluated the association of serum VWF antigen (Ag) level with stage cirrhosis (according to Child-Pugh classification). Materials and Methods:We included 82 cirrhotic patients (Female/ Male (F/M): 26/56) 86 healthy subjects (F/M: 44/42) study.Ages both groups were not different (P= 0.095).We excluded possible other reasons may cause increase.Diagnosis was made on basis...
Familial Mediterranean fever (FMF) is an autosomal recessive hereditary disease. Clinical symptoms and findings (phenotypes) seen in this disease are generally fever, abdominal pain, arthritis. Amyloidosis also a significant complication. Phenotype-genotype correlations FMF have not been conclusively resolved. The aims of study were to find the most frequent mutation/genotype FMF, as well investigate role genetic factors on phenotype development amyloidosis population living East Anatolia...
The aim of this study was to evaluate the long-term outcomes renal transplantation from Hbs Ag-positive donors Ag-negative recipients.A total 78 patients who underwent in our clinic between January 2006 and May 2014 were included study. Patients divided into 2 groups: Group 1: Donor Ag (+) (n=26, Ab (-), Hbe (+), Hbc Ig HBV DNA male/female (M/F): 16 (61.5%)/10 (38.5%), 2: (-) (n=52, M/F: 41 (78.8%)/11 (21.2%). levels similar recipients both groups. Data collected retrospectively. Analyses...
Patients who have vasculitis in pregnancy generally a grim prognosis. Vasculitis occurring during may more aggressive course and require treatment than at other times. A 29-year-old woman presented the 16th week of her third intrauterine was diagnosed as having active microscopic polyangiitis. Therapy consisting high-dose methylprednisolone cyclophosphamide instituted, but patient died pulmonary infection due to methicillin-resistant Staphylococcus aureus.
CD200 is a novel immune-effective molecule, existing in cell membrane-bound form, as well soluble form serum, which performs to modulate inflammatory and acquired immune responses. Autosomal dominant polycystic kidney disease (ADPKD) characterized by the development of large renal cysts progressive loss function. As defects cycle arrest apoptosis tubular epithelial cells occur ADPKD, we asked whether serum might underlie effect on ADPKD. Serum levels were measured 44 patients with ADPKD 24...
Background: The kidney is often affected in plasma cell dyscrasias, usually due to the effects of nephrotoxic monoclonal-free light chains. Renal failure a monoclonal gammopathy may be detected by highly sensitive serum-free light-chain (sFLC) ratio yet missed electrophoretic assays. aim this study was assess sFLC levels relation markers renal function. Methods: Five-hundred thirteen patients were included study. measured Freelite® (The Binding Site Group Ltd, Birmingham, UK) assay using...
The pathogenesis of familial Mediterranean fever (FMF) is unknown, and since no specific laboratory test yet available, the diagnosis FMF remains clinical. purpose this study was to review clinical characteristics patients with FMF.A total 96 were evaluated either retrospectively (for those diagnosed before 1997) or prospectively after 1997).The records 54 male 42 female studied. All Turks. Family history positive in 72 (75%). Involved site peritoneum 73 (76%), joints 65 (68%), pleura 16...
This study aims to determine fibroblast growth factor-23 and soluble α-Klotho levels in patients with autosomal dominant polycystic kidney disease. A total of 76 disease 32 healthy volunteers were included the study. Serum measured ELISA kits. Parathyroid hormone, phosphate, calcium, creatinine, 25-hydroxyvitamin D3 levels, urinary protein creatinine ratio estimated glomerular filtration rate also or calculated. Patients had significantly higher serum parathyroid hormone (p<0.001), (p=0.001)...
Neopterin is a diagnostic or prognostic biomarker for several pathologies including renal diseases. However, the association between neopterin status and causative main reasons such as diabetes hypertension disease remains unclear. The aim of study was to evaluate levels in patients treated with/without hemodialysis. According primary disorders, undergoing hemodialysis were classified into 4 groups diabetic nephropathy, hypertensive reflux nephropathy interstitial nephritis, others. controls...