A5068053402- Thyroid Disorders and Treatments
- Vitamin D Research Studies
- Selenium in Biological Systems
- Immunodeficiency and Autoimmune Disorders
- Digestive system and related health
- Psoriasis: Treatment and Pathogenesis
- Sleep and related disorders
- Circadian rhythm and melatonin
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Obesity, Physical Activity, Diet
- Metabolism and Genetic Disorders
- Autoimmune Bullous Skin Diseases
- Biomarkers in Disease Mechanisms
- Infectious Diseases and Tuberculosis
- Diabetes and associated disorders
- Salivary Gland Disorders and Functions
- Barrier Structure and Function Studies
- Pancreatitis Pathology and Treatment
- Nutrition, Health and Food Behavior
- Ophthalmology and Eye Disorders
- S100 Proteins and Annexins
- Oral Health Pathology and Treatment
- Human Health and Disease
- Sleep and Wakefulness Research
- Thyroid Cancer Diagnosis and Treatment
Riga Stradiņš University
2015-2024
Riga East University Hospital
2019
Autoimmune thyroid disease (AITD), including Graves' (GD) or Hashimoto's thyroiditis (HT), occurs due to genetic susceptibility and environmental factors, among which the role of stressful events remains controversial. This study investigated relationship between number impact life in AITD patients with selenium status, Th1/Th2/Th17 immune response. The population included three groups: HT (n = 47), GD 13), a control group 49). Thyroid function parameters, autoantibody levels, plasma levels...
T helper (Th) 17 cells and interleukin (IL)-17 play a significant role in the pathogenesis of autoimmune thyroid disease (AITD). However, it has recently become clear that Th17 are more heterogeneous exhibit two different phenotypes, whereas IL-23 IL-1β crucial for generation pathogenic lymphocytes. We aimed to investigate association between IL-17 Th17-promoting cytokines AITD by studying immunoexpression patterns IL-17, IL-23, tissue. Following thyroidectomy, 29 patients with (21 cases...
Th17 cells together with their hallmark cytokine interleukin (IL)-17 were identified as crucial contributing factors in the pathogenesis of thyroid autoimmunity. The cytokine-regulated tight junction (Tj) disruption is thought to be essential initiation and/or development several diseases. Still, role IL-17 maintaining Tj integrity autoimmune diseases (AITDs) has not yet been evaluated. We aimed investigate follicle by studying immunoexpression cellular - zonula occludens (ZO)-1 and...
Abstract Introduction The contribution of Th17 cytokines to autoimmune thyroid disease (AITD) is generally accepted. However, the roles cells in initiation and progression Hashimoto's thyroiditis (HT) Graves' (GD) remain unclear. Selenium deficiency, along with genetic predisposition environmental factors, may have a role autoimmunity. Aim We aimed assess (1) immune response by measuring plasma levels Th17‐ Treg‐associated (2) selenium status treatment‐naïve Latvian patients newly diagnosed...
Background and Objectives: Adequate dietary intake of iodine selenium is essential during pregnancy. While vital for maternal thyroid function fetal development, contributes to the regulation autoimmunity. This study aimed assess consumption iodine- selenium-containing products by women reproductive age nutritional status pregnant in Latvia. Materials Methods: Population health survey (2010-2018) data were used characterize habits age. Additionally, 129 first trimester recruited; they...
Abstract Autoimmune thyroid diseases (AITD) mainly include Hashimoto’s thyroiditis (HT) and Graves’ disease (GD), which are characterised by the presence of circulating antibodies against various autoantigens infiltration gland autoreactive lymphocytes. Despite significant advancement in knowledge AITD pathogenesis last decade, specific immunological mechanisms responsible for development not thoroughly understood. Classically, HT has long been considered as a T helper (Th)1-mediated...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Clinical: Therapy and observation S199The aim of this study is to evaluate the clinical endoscopic efficacy, safety infliximab therapy for UC following liver transplantation in patients with PSC.Methods: We evaluated all clear diagnosis who underwent Orthotopic Liver Transplantation (OLT) at Ospedali Riuniti Bergamo between January 2001 September 2012 had received inflixamab refractory IBD transplantation.Results: Four (all men; median age 39 years, range 22 54 years) (3) pouchitis (1) OLT...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Abstract There is a close relationship between melatonin as circadian regulator and insulin, glucagon somatostatin production. This study aimed to describe subgroups of type 2 diabetes mellitus (T2DM) patients that may benefit from clock-targeting properties. The involved 38 participants: 26 T2DM patients, 12 participants without in the control group. Subjects were asked complete questionnaire Pittsburgh Sleep Quality Index (PSQI). Standard biochemical venous sample testing was performed,...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)