A5061540513- Elasticity and Material Modeling
- Lower Extremity Biomechanics and Pathologies
- Tendon Structure and Treatment
- Diabetic Foot Ulcer Assessment and Management
- Pelvic floor disorders treatments
- Bariatric Surgery and Outcomes
- Urological Disorders and Treatments
- Urinary Bladder and Prostate Research
- Dental Implant Techniques and Outcomes
- Orthopaedic implants and arthroplasty
- Gastroesophageal reflux and treatments
- Automotive and Human Injury Biomechanics
- Bone Tissue Engineering Materials
- Foot and Ankle Surgery
- Dental materials and restorations
- Mechanical Engineering and Vibrations Research
- Osteoarthritis Treatment and Mechanisms
- Respiratory Support and Mechanisms
- Sports injuries and prevention
- Inhalation and Respiratory Drug Delivery
- Knee injuries and reconstruction techniques
- Corneal Surgery and Treatments
- Gastrointestinal motility and disorders
- Textile materials and evaluations
- Corneal surgery and disorders
University of Padua
2016-2025
Leeds Teaching Hospitals NHS Trust
2022-2023
University of Leeds
2022-2023
Osteoarthritis (OA) is one of the most common joint disorders. Evidence suggests that infrapatellar fat pad (IFP) directly involved in OA pathology. However, a comparison between versus non-OA IFP still missing. Thus, aim this study was to compare molecular, adipocytes and extracellular matrix characteristics patients affected by OA, undergoing anterior cruciate ligament (ACL) reconstruction. We hypothesized not only inflammation but also changes (ECM) composition might be pathogenesis....
Bladder cancer (BC) is among the most common malignancies in world and a relevant cause of mortality. BC one frequent causes for bladder removal through radical cystectomy, gold-standard treatment localized muscle-invasive some cases high-risk, non-muscle-invasive cancer. In order to restore urinary functionality, an autologous intestinal segment has be used create diversion. However, several complications are associated with bowel-tract removal, affecting patients’ quality life. The present...
Articular cartilage is a complex connective tissue with the fundamental functions of load bearing, shock absorption and lubrication in joints. However, traumatic events, aging degenerative pathologies may affect its structural integrity function, causing pain long-term disability. Osteoarthritis represents health issue, which concerns an increasing number people worldwide. Moreover, it has been observed that this pathology also affects mechanical behavior articular cartilage. To better...
A viscoelastic constitutive model for the periodontal ligament (PDL) capable of accounting large strains, anisotropy, and inelastic time-dependent effects was developed. Anisotropy characteristics are determined by composite nature tissue and, in particular, distribution collagen fibres. Time-dependent viscous phenomena due to microstructural modifications during loading, such as fluid fluxes moving through solid matrix internal rearrangement fibers adaptation. The presented here implemented...
The periodontal ligament (PDL), as other soft biological tissues, shows a strongly non-linear and time-dependent mechanical response can undergo large strains under physiological loads. Therefore, the characterization of behavior tissues entails definition constitutive models capable accounting for geometric material non-linearity. microstructural arrangement determines specific anisotropic properties. A hyperelastic formulation is adopted basis development PDL properly arranged...
Several studies have investigated cartilage degeneration and inflammatory subchondral bone synovial membrane changes using magnetic resonance (MR) in osteoarthritis (OA) patients. Conversely, there is a paucity of data exploring the role knee ligaments, infrapatellar fat pad (IFP), suprapatellar (SFP) OA compared to post-traumatic cohorts Therefore, aim this study was analyze volumetric morphometric characteristics following joint tissues: IFP (volume, surface, depth, femoral tibial arch...
Background: Nowadays, a challenging task concerns the biomechanical study of human lower urinary tract (LUT) due to variety its tissues and low availability samples. Methods: This work attempted further extend knowledge through comprehensive mechanical characterization male LUT by considering numerous harvested from same cadaver, including some never studied before. Samples bladder, urethra, prostate, Buck’s fascia tunica albuginea related corpora cavernosa were considered distinguished...
The aim was to investigate the biomechanical behaviour of colonic tissues by a coupled experimental and numerical approach. wall colon is composed different tissue layers. Within each layer, fibre families are distributed according specific spatial orientations, which lead strongly anisotropic configuration. Accounting for complex histology tissues, mechanical tests must be planned designed evaluate in directions. Uni-axial tensile were performed on specimens from 15 fresh pig colons,...
A constitutive framework is provided for the characterization of mechanical behavior colonic tissues, as a fundamental tool development numerical models structures. The analysis performed by multidisciplinary approach that requires cooperation between experimental and computational competences. preliminary investigation pertains to review tissues histology. complex structural configuration specific distributions fibrous elements entail nonlinear anisotropic response. identification...
What is the central question of this study? Prostheses for treatment urinary incontinence elicit complications associated with an inadequate mechanical action. This investigation aimed to define a procedure addressed urethral characterization. Experimental tests are basis constitutive formulation, view numerical modelling interaction between tissues and prosthesis. main finding its importance? Horse urethra, selected histomorphometric similarity human was characterized by integrated...