The presence of undesirable heavy metals, pesticide residues, and microbial contaminants in fresh produces is a worldwide public health concern. This study was undertaken to evaluate the residual pesticides (Diazinon, Malathion, Cypermethrin, Dimethoate, Quinalphos, Chloropyrofos), metal contamination (Pb, Cd, Cr), microbiological quality safety 4 common raw salad vegetables (RSVs) samples from different local markets Dhaka. Results showed metals residues were within acceptable limits...

Abstract In this study, we evaluated the ability of waste shell powder (WSP) and moringa seed (MSP) individually or in combination to eliminate dye, heavy metal resistant bacteria from industrial wastewater (IWW). The presence dyes, metals, approximately 7.0 log CFU/ml aerobic 3.0–4.0 other pathogens including Escherichia coli , Pseudomonas aeruginosa Citrobacter freundii Serratia liquefaciens Bacillus cereus was evident IWW both tannery textile industries. addition, depending on type...

In recent years, small molecule inhibition of LDHA (Lactate Dehydrogenase A) has evolved as an appealing option for anticancer therapy. catalyzes the interconversion pyruvate and lactate in glycolysis pathway to play a crucial role aerobic glycolysis. Therefore, current investigation was targeted with bioactive phytochemicals ethnomedicinally important plant species Oroxylum indicum (L.) Kurz. A total 52 were screened against protein through molecular docking, ADMET (Absorption,...

The etiology of cervical cancer in women is attributed to the continuous infection human papillomavirus (HPV). high costs and side effects standard treatments limited efficacy HPV vaccination have led a quest for novel, cost-effective treatments, particularly middle- low-income countries. Therefore, our objective was evaluate capacity marine seaweed compounds hinder activity E6 Oncoprotein. Seaweed Metabolite Database evaluated its ability inhibit Oncoprotein functions by throughput virtual...

Colorectal cancer (CRC) is one of the leading causes cancer-related mortality globally. The rising expenses, significant side effects, and increasing resistance to traditional CRC treatments suggest critical need for new more effective therapeutic options. This study explored anticancer potential Lannea coromandelica (Houtt.) Merr. phytocompounds targeting promising apoptosis signal-regulatory kinase 1 (ASK1) protein using computational biology approaches including molecular docking, ADMET...

Scaphium scaphigerum (Wall. ex G. Don) Planch. is a threatened medicinal tree of Bangladesh, belonging to the family Malvaceae. This study unveiled first chloroplast genome species, spanning 160,927 bp with GC content 36.89%. The plastome exhibited typical orbicular quadripartite structure angiosperms, consisting pair inverted repeat regions (25502 bp), isolated by large-single copy region (90012 bp) and small single-copy (19911 bp). harbored 128 genes in total, including 85 protein-coding...

Cancer is one of the leading causes death due to its very high rate morbidity and mortality, there a constant demand effective drugs for cancer therapy. Vascular endothelial growth factor receptor-2 (VEGFR-2) plays significant role as central modulator angiogenesis targeted frequently developing anti-angiogenic agents fight cancer. Helicteres isora L. (Malvaceae) reported possess diverse medicinal properties including anti-cancer potentials. In current investigation, 38 bioactive...

Infectious Spleen and Kidney Necrosis Virus (ISKNV) is linked to severe infections that cause significant financial losses in global aquaculture. ISKNV enters the host cell through its major capsid protein (MCP), resulting infection can lead mass mortality of fish. Even though several drugs vaccines are at various stages clinical testing, none currently available. Thus, we sought assess potential seaweed compounds block viral entrance by inhibiting MCP. The Seaweed Metabolite Database (1110...

It is evident that date fruits provide a wide variety of essential nutrients which impart potential human health benefits. In Bangladesh, the popularity and its consumption surge few-fold during Ramadan among Muslims owing to profound emotion related religious belief breaking dawn-to-dusk fasting with dates fulfilling Sunnah. The present study aimed explore microbiological quality five most popular fresh samples (Nagal, Dhapas, Boroi, Morium, Tunisia) purchased from different locations Dhaka...

Addition to the angiosperm flora provides essential insights into biodiversity of a region, contributing ecological understanding and conservation planning. Gafargaon subdistrict under Mymensingh district in Bangladesh represents diverse population angiosperms with multifaceted ecosystem that demands re-evaluation existing diversity update status taxa facilitate their efforts. With this endeavor, total 100 belonging 90 genera 46 families were uncovered as additional occurrence Gafargaon. The...

The underdeveloped countries with large populations are facing a grave global threat in the form of cholera.

The SARS-CoV-2 has severely impacted the lives of people worldwide. Global concern is on rise due to a large number unexpected mutations in viral genome, resulting new variants. Nature-based bioactive phytochemicals hold great promise as inhibitors against pathogenic viruses. current study was aimed at evaluating some antiviral variants concern. A total 46 were screened spike protein Alpha, Beta, Delta, Gamma, and Omicron In addition molecular docking, screening for favorable pharmacokinetic...

Vibrio cholerae, the etiological agent of cholera, causes dehydration and severe diarrhea with production cholera toxin. Due to acquired antibiotic resistance, V. cholerae has drawn attention establishment novel medications counteract virulence viability pathogen. Centella asiatica is a medicinal herb native Bangladesh that wide range ethnobotanical applications including anti-bacterial properties. In present investigation, total 25 bioactive phytochemicals C. have been screened virtually...

A molecular phylogenetic investigation was undertaken for 30 species belonging to 15 genera of the palm family Arecaceae in Bangladesh infer evolutionary relationships and dating utilizing plastid-based matK rbcL genes through multifaceted-algorithm driven approaches with Neighbor-Joining, Maximum-Likelihood, Bayesian Inference methods. The study revealed that has better discrimination efficiency than gene due its highly variable nature. Transition/transversion bias test corroborated this...

Chagas disease is a tropical ailment indigenous to South America and caused by the protozoan parasite Trypanosoma cruzi, which has serious health consequences globally. Insect vectors transmit and, due lack of vaccine availability limited treatment options, we implemented an integrated core proteomics analysis design reverse candidate based on immune epitopes for control. Firstly, T. cruzi was used identify immunodominant epitopes. Therefore, designed sequence be non-allergic, antigenic,...

The present investigation unveiled the first complete chloroplast (cp) genome of Tribulus macropterus var. arabicus (Hosni) Al-Hemaid & J. Thomas (Zygophyllaceae), a medicinal herb, indigenous to Saudi Arabia. cp genome, comprising length 158,179 bp and GC content 35.8%, exhibited typical circular quadripartite arrangement flowering plants, including two inverted repeat regions (25842 bp) separated by large single-copy (88873 small region (17622 bp). Genome annotation unraveled 132...

Taxonomic revision and morphometrics are two crucial facets for the proper identification, updating of taxa, strengthening phenetic relationships angiosperms. This study focused on systematics subfamily Byttnerioideae Burnett (Family Malvaceae) first time in Bangladesh, revealing eight taxa under seven genera, namely Abroma Jacq., Ayenia L., Guazuma Mill., Kleinhovia Melochia Theobroma L. Waltheria These genera fall into three tribes: Byttnerieae, Theobromateae, Hermannieae. Dichotomous...

Lepidocephalichthys guntea, commonly known as loach, is a popular freshwater fish found in various water bodies. This study collected 210 specimens (148 females, 62 males) from markets Noakhali, Bangladesh, to measure length, weight, gonado-somatic index (GSI), fecundity and condition factor. To establish correlations, the relationships between length-length, length-weight, GSI with both length weight were analyzed. Body ranged 1.99 8.89 g (mean 4.21 ± 1.49 g), total 6.5 10.3 cm 7.91 0.77...

The present study explores the angiosperm flora belonging to class Liliopsida in Rajbari district, seamlessly integrating taxonomy with phytocompound-based drug discovery through advanced computational biology approaches. covered all five upazilas (sub-districts) of district. A total 201 taxa across 118 genera and 24 families were identified. is predominantly composed herbs (79.06%), followed by climbers (7.96%), trees (7.46%), shrubs (2.98%), a minimal occurrence epiphytes (1.99%). Poaceae...