A5007842672- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Mental Health Research Topics
- Traumatic Brain Injury Research
- Trauma and Emergency Care Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Posttraumatic Stress Disorder Research
- Heart Rate Variability and Autonomic Control
- EEG and Brain-Computer Interfaces
- Digital Mental Health Interventions
- Traumatic Brain Injury and Neurovascular Disturbances
- Impact of Light on Environment and Health
- Cell Image Analysis Techniques
- Parkinson's Disease Mechanisms and Treatments
- Treatment of Major Depression
- Psychosomatic Disorders and Their Treatments
- Optical Imaging and Spectroscopy Techniques
- Transcranial Magnetic Stimulation Studies
- Cardiac Arrest and Resuscitation
- Alzheimer's disease research and treatments
- Circadian rhythm and melatonin
- Advanced Graph Neural Networks
- Amyotrophic Lateral Sclerosis Research
- Brain Tumor Detection and Classification
The University of Texas at Austin
2018-2024
Texas Research Institute
2018-2019
University of Arizona
2015-2017
Neuroscience is advancing standardization and tool development to support rigor transparency. Consequently, data pipeline complexity has increased, hindering FAIR (findable, accessible, interoperable reusable) access. brainlife.io was developed democratize neuroimaging research. The platform provides standardization, management, visualization processing automatically tracks the provenance history of thousands objects. Here, described evaluated for validity, reliability, reproducibility,...
Prolonged exposure to blue wavelength light has been shown have an alerting effect, and enhances performance on cognitive tasks. A small number of studies also that relatively short leads changes in functional brain responses during the period exposure. The extent which continues affect functioning a cognitively challenging task after cessation longer periods (i.e., roughly 30 minutes or longer), however, not fully investigated. total 35 healthy participants (18 female) were exposed either...
Abstract Background Some Internet interventions are regarded as effective treatments for adult depression, but less is known about who responds to this form of treatment. Method An elastic net and random forest were trained predict depression symptoms related disability after an 8-week course intervention, Deprexis, involving adults ( N = 283) from across the USA. Candidate predictors included psychopathology, demographics, treatment expectancies, usage, environmental context obtained...
Abstract Using brain atlases to localize regions of interest is a requirement for making neuroscientifically valid statistical inferences. These atlases, represented in volumetric or surface coordinate spaces, can describe topology from variety perspectives. Although many human have circulated the field over past fifty years, limited effort has been devoted their standardization. Standardization facilitate consistency and transparency with respect orientation, resolution, labeling scheme,...
Thalamocortical connectivity is believed to underlie basic alertness, motor, sensory information processing, and attention processes. This appears be disrupted by total sleep deprivation, but it not known whether affected normal variations in general daytime sleepiness nonsleep deprived persons. Healthy adult participants completed the Epworth Sleepiness Scale underwent resting-state functional MRI. Functional between thalamus other regions of cortex was examined correlated with scores....
Brooding, which refers to a repetitive focus on one's distress, is associated with functional connectivity within Default-Mode, Salience, and Executive-Control networks (DMN; SN; ECN), comprising the so-called "triple-network" of attention. Individual differences in brain structure that might perseverate dysfunctional brooding are less clear, however. Using diffusion Magnetic Resonance Imaging, we explored multimodal relationships between severity, white-matter microstructure, resting-state...
Individuals differ in their ability to understand emotional information and apply that understanding make decisions solve problems effectively – a construct known as Emotional Intelligence (EI). While considerable evidence supports the importance of EI social occupational functioning, neural underpinnings this capacity are relatively unexplored. We used Tract-Based Spatial Statistics (TBSS) determine white matter correlates measured by ability-based Mayer–Salovey–Caruso Test (MSCEIT)....
Abstract Using brain atlases to localize regions of interest is a requirement for making neuroscientifically valid statistical inferences. These atlases, represented in volumetric or surface coordinate spaces, can describe topology from variety perspectives. Although many human have circulated the field over past fifty years, limited effort has been devoted their standardization. Standardization facilitate consistency and transparency with respect orientation, resolution, labeling scheme,...
Abstract Depressive Rumination (DR), which involves a repetitive focus on one’s distress, has been linked to alterations in functional connectivity of the ‘triple-network’, consisting Default-Mode, Salience, and Executive Control networks. A structural basis for these that can dually explain DR’s persistence as stable trait remains unexplored, however. Using diffusion Magnetic Resonance Imaging, we investigated multimodal relationships between DR severity, white-matter microstructure,...
Posttraumatic stress disorder (PTSD) develops in a substantial minority of emergency room admits. Inexpensive and accurate person-level assessment PTSD risk after trauma exposure is critical precursor to large-scale deployment early interventions that may reduce individual suffering societal costs. Toward this aim, we applied ensemble machine learning predict status three months severe injury using cost-effective minimally invasive data. Participants (N = 271) were recruited at Level 1...
Theoretical models and empirical research point to negatively biased attention as a maintaining factor in depression. Although preliminary studies suggest experimentally modifying attentional biases (i.e., bias modification; ABM) reduces depression symptoms risk, relatively few rigorous with clinical samples have been completed. This trial examines the impact of ABM on sample adults (N = 123) elevated severity who also exhibit at least modest levels prior treatment. Participants will be...
Abstract Connectomics—the study of brain networks—provides a unique and valuable opportunity to the brain. Research in human connectomics, leveraging functional diffusion Magnetic Resonance Imaging (MRI), is resource-intensive practice. Typical analysis routines require significant computational capabilities subject matter expertise. Establishing pipeline that low-resource, easy use, off-the-shelf (can be applied across multifarious datasets without parameter tuning reliably estimate...
Mild traumatic brain injury (mTBI) is often associated with sleep problems. However, little known about the relationship between problems, post-concussion symptom severity, and common cognitive deficits such as difficulties verbal fluency when given a category. We investigated whether post-concussive severity was problems in sample of recent concussion survivors. 26 adults (11 males; 18–45 years old) documented history mTBI within preceding 12 months underwent comprehensive...
A complete understanding of human behavior and disease depends upon our ability to parse genetic environmental influences in the brain. The heritability a trait quantifies degree its variability due influences. Classical approach for quantifying operate on simple traits, sometimes do not properly model control other potential sources variation, such as age or sex. We therefore develop Causal Heritability Networks (CHaiN) rigorously quantify brain networks (i.e., connectomes). applied CHaiN...
We develop an open-source tool for the retrospective estimation of inter-volume head-motion and eddy-current distortions, typically found in diffusion MRI (dMRI) data acquired with echo-planar imaging schemes. The implementation is “open-since-inception” to ensure transparency. By leveraging widely used DIPY package a user-friendly interface, researchers have at their disposal combining state-of-art approaches substantial improvements that can efficiently leverage any compliant model(s)...