A5063943673- Periodontal Regeneration and Treatments
- Reconstructive Surgery and Microvascular Techniques
- Multiple Sclerosis Research Studies
- Bone and Joint Diseases
- Knee injuries and reconstruction techniques
- Molecular Communication and Nanonetworks
- Wireless Body Area Networks
- Streptococcal Infections and Treatments
- Shoulder and Clavicle Injuries
- Tissue Engineering and Regenerative Medicine
- Parvovirus B19 Infection Studies
- Hip disorders and treatments
- Polyomavirus and related diseases
- Corneal Surgery and Treatments
- Mesenchymal stem cell research
- Transcranial Magnetic Stimulation Studies
- Hemoglobinopathies and Related Disorders
- Oral and gingival health research
- Electrospun Nanofibers in Biomedical Applications
- Platelet Disorders and Treatments
- Autoimmune and Inflammatory Disorders Research
- Shoulder Injury and Treatment
- Autoimmune Bullous Skin Diseases
- Mosquito-borne diseases and control
- Head and Neck Surgical Oncology
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2004-2025
Universidade de São Paulo
2023-2025
Deoxi Biotecnologia (Brazil)
2023
Angiogenesis Foundation
2007
Background: Severe yellow fever (YF) can result in acute liver failure (ALF) and high mortality. The role of therapeutic plasma exchange (TPE) managing YF-ALF remains unclear. This study evaluated the impact TPE strategies severe YF. Methods: observational case-series three groups patients classified according to treatment: G1 (standard intensive care support [ICS]), G2 (ICS + high-volume-TPE [HV-TPE]), G3 TPE). HV-TPE was performed during 3 consecutive days with extra sessions one...
Azacitidine is a hypomethylating agent recommended for the treatment of patients with high-risk myelodysplastic syndromes. Here, we report case patient syndrome who was not eligible allogeneic stem cell transplantation (allo-SCT) and presented rare previously unreported cutaneous side effect after use subcutaneous azacitidine. We propose that changing route azacitidine administration from to intravenous could potentially decrease occurrence bullous pemphigoid-like localized toxic reactions...
Abstract: In order to increase the amount of available bone where dental implants must be placed, present study has associated platelet‐rich plasma (PRP) and mononuclear cells (MNCs) from marrow aspirate scaffold (BS) in 32 patients aged between 45 75 years old. The MNC attainment adherence BS were confirmed through histology, cell culture, scanning electron microscopy. clinical results, analyzed by computed tomography, have showed that scaffolds well integrated adapted cortical bone. We can...
Platelet-rich plasma (PRP) has the capacity to improve bone-healing process. The aim of this pilot study was investigate occurrence bone healing and time taken achieve in patients submitted medial opening wedge high tibial osteotomy (MOWHTO), comparing platelet-rich with marrow aspirate autologous iliac graft.Twenty-five who underwent were randomly divided into 2 groups: a control group, which received grafts (14 patients), compound PRP (11 patients).The rates achieved 100% group 91% group....
OBJETIVO: Avaliar se a injeção intra-articular de Plasma rico em plaquetas (PRP) pode reduzir apoptose pós-traumática condrócitos. MÉTODOS: Foi desenvolvido um estudo experimental duplo-cego com quatro joelhos coelhos adultos. Após anestesia, os animais foram submetidos à contusão padronizada dos joelhos. Depois foi injetado 1ml PRP humano nos dois esquerdos e solução fisiológica (SF) direitos. Os mantidos no mesmo ambiente sob controle temperatura, atividades diárias alimentação. A...
Abstract Background Alpha‐1‐antitrypsin is the principal serum protease inhibitor. In addition to well‐recognized association with early‐onset emphysema and cirrhosis, alpha‐1‐antitrypsin deficiency may be associated panniculitis. The treatment of this type panniculitis presents a significant challenge. Previous attempts using immunosuppressive, anti‐inflammatory, cytotoxic drugs have shown variable results. Aim To report case deficiency‐associated treated plasma exchange therapy. Methods A...
The present study was performed in order to evaluate the use of platelet rich plasma associated bone marrow aspirate, substituting autologous iliac graft medial opening wedge osteotomy (OWHTO).Twenty-five patients were submitted tibial osteotomy, being divided into two groups. Iliac group: 14 OWHTO, using fill gap. PRP 11 aspirate We evaluated bleeding (hemoglobin and hematocrit levels) pain (visual analogic scale-VAS), then we compared groups regarding these variables.Differences between...
ABSTRACT Objective: To describe a protocol of obtention mesenchymal stem cells and to report their use as biological adjuvant in three patients undergoing arthroscopic rotator cuff repair. Methods: Case series who underwent repair isolated full-thickness supraspinatus tear using obtained from the bone marrow adjuvant. All were operated on at same institution, by surgeon with 13 years experience. The applied end procedure, tendon-bone interface, an approximate concentration 2,000,000...
OBJETIVO: O presente estudo procurou avaliar a aplicação do plasma rico em plaquetas associado ao aspirado de medular óssea como substituto ósseo enxerto autólogo ilíaco nas osteotomias tibiais proximais cunha adição medial (OTCAM). MÉTODOS: Foram estudados 25 pacientes submetidos OTCAM divididos forma randomizada dois grupos, grupo ilíaco, 14 nos quais se utilizou o para preencher sitio da osteotomia, PRP, 11 um composto formado por osteotomia. avaliados sangramento (variação dos níveis...
In order to assure corneal transparency after injury the effective removal of myofibroblasts is fundamental. The display platelet activator factor receptor on its surface. concentrate one richest sources essential growth factors, reducing bleeding, inflammation, scaring time, thus speeding up closing ulcers. We report a case which provides evidence clinical improvement with eyedrops non responsive trophic disease. Use for ocular surface [...]