A5007088509- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Spinal Cord Injury Research
- Scoliosis diagnosis and treatment
- Pelvic and Acetabular Injuries
- Nerve Injury and Rehabilitation
- Musculoskeletal pain and rehabilitation
- Management of metastatic bone disease
- Spinal Dysraphism and Malformations
- Cervical and Thoracic Myelopathy
- Medical Imaging and Analysis
- Cerebral Palsy and Movement Disorders
- Orthopedic Surgery and Rehabilitation
- Shoulder and Clavicle Injuries
- Shoulder Injury and Treatment
- Infectious Diseases and Tuberculosis
- Trauma and Emergency Care Studies
- Mesenchymal stem cell research
- Bone fractures and treatments
- Spinal Hematomas and Complications
- Bone Tumor Diagnosis and Treatments
- Diabetic Foot Ulcer Assessment and Management
- Sarcoma Diagnosis and Treatment
- Anesthesia and Pain Management
- Trauma Management and Diagnosis
Universidade de São Paulo
2016-2025
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2015-2024
National Institute of Traumatology & Orthopaedic Rehabilitation
2023
Associação de Assistência à Criança Deficiente
2022
Hospital de Clínicas
2021
Instituto do Câncer do Estado de São Paulo
2018-2020
Clinical Orthopaedics and Related Research
2019
Committee on Publication Ethics
2019
Universidade Brasil
2007-2015
Centro Universitário das Faculdades Metropolitanas Unidas
2011
To evaluate the functional and immunohistochemical effects of ganglioside GM1 erythropoietin following experimental spinal cord injury.Thirty-two male BALB/c mice were subjected to injury using NYU Impactor device randomly divided into groups: group, receiving standard (30 mg/kg); (1000 IU/kg); combination both drugs; control saline (0.9%). Animals evaluated according Basso Mouse Scale (BMS) Hindlimb Function Score (MFS). After euthanasia, immunohistochemistry medullary tissue was analyzed....
Mesenchymal stem cells (MSCs) are multipotent with the potential to differentiate into various lineages. They have also protect themselves against harmful stimuli maintain their functional integrity. Drug resistance-related transporters such as ABCB1 (P-glycoprotein; P-gp), ABCC1 (MRP1; multidrug Protein 1), and LRP (lung resistance protein) may MSCs toxic substances chemotherapeutic agents. This study evaluated ABCB1, ABCC1, before after differentiation of derived from human amniotic fluid...
OBJECTIVES:To evaluate the interobserver agreement for Neoplastic Spine Instability Score (SINS) among spine surgeons with or without experience in vertebral metastasis treatment and physicians other specialties.METHODS: Case descriptions were produced based on medical records of 40 patients metastases.The then published online.Physicians invited to by answering questions according (SINS).The was calculated using kappa coefficient.RESULTS: Seventeen agreed participate: three highly...
The objective was to compare the traditional microdiscectomy with percutaneous endoscopic lumbar discectomy for treatment of disc herniations regarding pain, disability, and complications.Randomized clinical trial 47 patients treated 2 different surgical techniques: or discectomy. Forty-seven were divided into groups monitored 12 months. Irradiated low back pain evaluated visual analog scale. Surgery complications recorded.After surgery, sciatica disability improved significantly but without...
Currently, there is a lack of effective therapeutic methods to restore neurological function for chronic complete spinal cord injury (SCI) by conventional treatment. Neurorestorative strategies with positive preclinical results have been translated the clinic, and some patients gotten benefits their quality life has improved. These include cell therapy, neurostimulation or neuromodulation, neuroprosthesis, neurotization nerve bridging, neurorehabilitation. The aim this consensus 31 experts...
In Brief Study Design. The report of a rare case lead poisoning by an intradiscal firearm bullet is presented. Objective. To describe and discuss the clinical radiologic features (by computed tomography magnetic resonance imaging) gunshot wound in L2–L3 space which caused 5 years afterwards. Summary Background Data. Lead from bullets rare, but possibility should be investigated lodged joints. Methods. A 30-year-old man presented to emergency room with intense lumbar pain complaint, colic,...
There are several techniques for screw insertion in upper cervical spine surgery, and the use of 3.5-mm is usually standard. However, there no consensus regarding feasibility using these screws pediatric population.To determine measurement lamina angle, pedicle length thickness, lateral mass topographic axial view axis vertebra 2- to 10-year-old children guide surgical screws.Seventy-five computed tomography scans from 24- 120-month-old patients were studied. Measurements taken an C2...
OBJECTIVE:To evaluate the association of clinical and demographic variables in patients requiring blood transfusion during elective surgery to treat scoliosis with aim identifying markers predictive need for transfusion.METHODS: Based on review medical charts at a public university hospital, this retrospective study evaluated whether following were associated red cell (measured by number packs used) surgery: scoliotic angle, extent arthrodesis (number fused levels), sex patient, duration...
To evaluate the functional and histological effects of estrogen as a neuroprotective agent after standard experimentally induced spinal cord lesion.In this experimental study, 20 male Wistar rats were divided into two groups: one group with undergoing injury (SCI) at T10 receiving therapy 17-beta estradiol (4mg/kg) immediately following placement skin sutures control only subjected to SCI. A moderate SCI was produced using computerized device that dropped weight on rat's spine from height...
Abstract During the progression of neurodegenerative process, mitochondria participates in several intercellular signaling pathways. Voltage-dependent anion-selective channel 1 (VDAC1) is a mitochondrial porin involved cellular metabolism and apoptosis intrinsic pathway many neuropathological processes. In spinal cord injury (SCI), after primary cell death, secondary response that comprises release pro-inflammatory molecules triggers apoptosis, inflammation, demyelination, often leading to...
Pain generator-based lumbar spinal decompression surgery is the backbone of modern spine care. In contrast to traditional image-based medical necessity criteria for surgery, assessing severity neural element encroachment, instability, and deformity, staged management common painful degenerative conditions likely be more durable cost-effective. Targeting validated pain generators can accomplished with simplified procedures associated lower perioperative complications long-term revision rates....
: The primary purpose of this study was to determine the characteristics and outcomes patients admitted at our clinics diagnosed with cauda equina syndrome (CES). Secondarily, will serve as a basis for other comparative studies aiming better understanding condition its epidemiology.: We conducted retrospective by reviewing medical records CES neurogenic bladder between 2005 2011. following variables were analyzed: gender, age, etiology, topographic level lesion, time disease onset diagnosis,...
To evaluate cases of traumatic spondylolisthesis the axis and describe them in relation to epidemiology, classification, neurological deficit, healing time treatment method.A retrospective analysis medical records patients treated between 2002 2010 at IOT-FMUSP.pars interarticularis fracture C2.68% were male patients, with a mean age 39.1 years. We used classification by Effendi, modified Levine-Edwards. Type I fractures observed five (31.2%) type II eight (50%). Only three (18%) had IIa...
OBJECTIVES:To verify the incidence of facetary and low back pain after a controlled medial branch anesthetic block in three-month follow-up to correlation between positive results demographic variables.METHODS: Patients with chronic lumbar underwent sham blockade (with saline injection) then block.Their symptoms were evaluated before injection real block; reevaluated one day week, as well one, two three months using visual analog scale.We searched for an association characteristics...