A5100621625- Mesenchymal stem cell research
- Autism Spectrum Disorder Research
- Pluripotent Stem Cells Research
- Spinal Cord Injury Research
- Nerve injury and regeneration
- Nerve Injury and Rehabilitation
- Spinal Fractures and Fixation Techniques
- Sarcoma Diagnosis and Treatment
- Cerebral Palsy and Movement Disorders
- Neurogenetic and Muscular Disorders Research
- Muscle Physiology and Disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Spinal Hematomas and Complications
- Renal Diseases and Glomerulopathies
- Spinal Dysraphism and Malformations
- Soft tissue tumor case studies
- Genetics and Neurodevelopmental Disorders
- Oral and Maxillofacial Pathology
- Case Reports on Hematomas
- Cancer and Skin Lesions
- Cerebrospinal fluid and hydrocephalus
- Stroke Rehabilitation and Recovery
- Neurogenesis and neuroplasticity mechanisms
- Bone Tumor Diagnosis and Treatments
- Cardiac Valve Diseases and Treatments
All India Institute of Medical Sciences Jodhpur
2019-2024
Neurogen Brain & Spine Institute
2014-2024
All India Institute of Medical Sciences, Nagpur
2024
Post Graduate Institute of Medical Education and Research
2016-2024
Creative Commons
2024
Atal Bihari Vajpayee Indian Institute of Information Technology and Management
2024
University of Pennsylvania Health System
2024
Lokmanya Tilak Municipal General Hospital and Lokmanya Tilak Municipal Medical College
2011-2023
Medical College of Wisconsin
2023
Pacific Dental College and Hospital
2023
Cellular therapy is an emerging therapeutic modality with a great potential for the treatment of autism. Recent findings show that major underlying pathogenetic mechanisms autism are hypoperfusion and immune alterations in brain. So conceptually, cellular which facilitates counteractive processes improving perfusion by angiogenesis balancing inflammation regulation would exhibit beneficial clinical effects patients This open label proof concept study autologous bone marrow mononuclear cells...
Neurological disorders such as muscular dystrophy, cerebral palsy, and injury to the brain spine currently have no known definitive treatments or cures. A study was carried out on 71 children suffering from incurable neurological injury. They were intrathecally intramuscularly administered autologous bone marrow-derived mononuclear cells. Assessment after transplantation showed improvements in muscle power a shift assessment scales FIM Brooke Vignos scale. Further, imaging...
The purpose of this multicenter observational clinical study was to evaluate the performance a near-infrared (NIR)-based, non-invasive, portable device screen for traumatic intracranial hematomas. Five trauma centers collected data using NIR at time computed tomography (CT) scan performed suspected brain injury (TBI). CT scans were read by an independent neuroradiologist who blinded measurements. Of 431 patients enrolled, 365 included in per-protocol population analyzed. patients, 96...
Cerebral palsy is a nonprogressive heterogeneous group of neurological disorders with growing rate prevalence. Recently, cellular therapy emerging as potential novel treatment strategy for cerebral palsy. The various mechanisms by which works include neuroprotection, immunomodulation, neurorestoration, and neurogenesis. We conducted an open label, nonrandomized study on 40 cases aim evaluating the benefit in combination rehabilitation. These were administered autologous bone marrow...
Cell therapy is being widely explored in the management of stroke and has demonstrated great potential. It been shown to assist remodeling central nervous system by inducing neurorestorative effect through process angiogenesis, neurogenesis, reduction glial scar formation. In this study, intrathecal administration autologous bone marrow mononuclear cells (BMMNCs) analyzed on recovery patients with chronic stroke. 24 diagnosed were administered cell therapy, followed multidisciplinary...
Cell therapy has been shown to be a key clinical therapeutic option for central nervous system diseases or damage. Standardization of cell procedures is an important task professional associations devoted therapy. The Chinese Branch the International Association Neurorestoratology (IANR) completed first set guidelines governing application neurorestoration in 2011. IANR and (CANR) collaborated propose current version "Clinical Therapy Guidelines Neurorestoration (IANR/CANR 2017)". council...
Muscular dystrophy is a genetic disorder with no definite cure. A study was carried out on 150 patients diagnosed muscular dystrophy. These included Duchenne dystrophy, limb-girdle and Becker variants. They were administered autologous bone marrow-derived mononuclear cells intrathecally intramuscularly at the motor points of antigravity weak muscles followed by vigorous rehabilitation therapy. No significant adverse events noted. Assessment after transplantation showed neurological...
Traumatic brain injury is an to the parenchyma resulting from external factors such as vehicular accidents, falls, or sports injuries. Its outcome involves primary insult followed by a cascade of secondary insult, in diffuse axonal further causing white matter damage. Surgical intervention targets damage, whereas only few treatment alternatives are available treat Cellular therapy could be one prospective therapeutic options, it has potential arrest degeneration and promote regeneration new...
Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's (PD), Huntington's (HD), and epilepsy sickness, currently impact millions of people globally. Thus yet, the primary etiology these ailments has not been determined. Regretfully, no medication can prevent onset illnesses. The risk factor for illnesses developing is age. Recently, there an increase in interest among researchers to investigate potential therapeutic benefits herbal remedies neurodegenerative diseases....
Tuberculosis is endemic in developing countries. However, calvarial tuberculosis rare, even areas where endemic. In the literature, only few case series of have been reported.To report a 11 patients with tuberculosis, and discuss their presentation management.This study retrospective analysis records treated between 2001 2005 tertiary hospital. Clinical features, radiological findings, surgical medical management, outcomes were reviewed.Of patients, seven male age ranged 1 25 years (mean...
<b>Background:</b> Crescentic glomerulonephritis (CrGN), defined as crescents involving more than 50% of the glomeruli, includes pauci-immune, immune complex-mediated and anti-glomerular basement membrane disease. <b>Objectives:</b> The present study was aimed at evaluating various clinical, biochemical histological parameters in CrGN with respect to these categories clinical outcome. <b>Materials Methods:</b> Renal biopsies diagnosed between Jan 2008 Feb 2010 were included. Clinical...
Currently, there is a lack of effective therapeutic methods to restore neurological function for chronic complete spinal cord injury (SCI) by conventional treatment. Neurorestorative strategies with positive preclinical results have been translated the clinic, and some patients gotten benefits their quality life has improved. These include cell therapy, neurostimulation or neuromodulation, neuroprosthesis, neurotization nerve bridging, neurorehabilitation. The aim this consensus 31 experts...