A5045060999- Mesenchymal stem cell research
- Muscle Physiology and Disorders
- Cerebral Palsy and Movement Disorders
- Prosthetics and Rehabilitation Robotics
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurogenesis and neuroplasticity mechanisms
- Muscle activation and electromyography studies
- Stroke Rehabilitation and Recovery
- Diabetic Foot Ulcer Assessment and Management
- Nerve injury and regeneration
Neurogen Brain & Spine Institute
2014-2016
Cerebral palsy is a nonprogressive heterogeneous group of neurological disorders with growing rate prevalence. Recently, cellular therapy emerging as potential novel treatment strategy for cerebral palsy. The various mechanisms by which works include neuroprotection, immunomodulation, neurorestoration, and neurogenesis. We conducted an open label, nonrandomized study on 40 cases aim evaluating the benefit in combination rehabilitation. These were administered autologous bone marrow...
Cell therapy is being widely explored in the management of stroke and has demonstrated great potential. It been shown to assist remodeling central nervous system by inducing neurorestorative effect through process angiogenesis, neurogenesis, reduction glial scar formation. In this study, intrathecal administration autologous bone marrow mononuclear cells (BMMNCs) analyzed on recovery patients with chronic stroke. 24 diagnosed were administered cell therapy, followed multidisciplinary...
Abstract: Limb girdle muscular dystrophy (LGMD), a group of progressive degenerative disorders, causes functional limitation affecting the quality life. Cell therapy is being widely explored and preliminary studies have shown beneficial effects. induces trophic-factors release, angiogenesis, anti-inflammation, protein synthesis, which helps in reparative process at microcellular level. In this 5-year longitudinal study, effect autologous bone marrow mononuclear cells studied on natural...
Introduction: Ischemic stroke is brain injury due to hypoperfusion leading sudden neurological symptoms. Despite advances in medicine, prognosis still grim especially with chronic residual neurodeficits. Autologous bone marrow mononuclear cells (BMMNCs) transplantation safe and has shown positive outcomes previous studies of ischemic stroke. Our aim was study the effect autologous BMMNCs Intervention Results: We treated a case pontine infarct three years later, followed by standard...