A5061606034- Glioma Diagnosis and Treatment
- Cancer Cells and Metastasis
- Electromagnetic Fields and Biological Effects
- Spinal Cord Injury Research
- Cancer Research and Treatments
- Immunotherapy and Immune Responses
- Mesenchymal stem cell research
- Chemical Reactions and Isotopes
- Neuroblastoma Research and Treatments
- Immune cells in cancer
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurogenesis and neuroplasticity mechanisms
- Amyotrophic Lateral Sclerosis Research
- Cancer Diagnosis and Treatment
- Hematopoietic Stem Cell Transplantation
- Bone health and treatments
- Biofield Effects and Biophysics
- Pluripotent Stem Cells Research
- Cancer, Hypoxia, and Metabolism
- Microtubule and mitosis dynamics
- Neurogenetic and Muscular Disorders Research
- Spinal Dysraphism and Malformations
- Spine and Intervertebral Disc Pathology
- Traumatic Brain Injury Research
- Ultrasound and Hyperthermia Applications
NeuroVita Clinic
2012-2024
Central Clinical Hospital and Polyclinic
2018-2020
Federal Medical-Biological Agency
2015-2019
Far Eastern Federal University
2014-2016
State Research Institute of Highly Pure Biopreparations
2015
Creative Research Enterprises (United States)
2015
Cell therapy has been shown to be a key clinical therapeutic option for central nervous system diseases or damage. Standardization of cell procedures is an important task professional associations devoted therapy. The Chinese Branch the International Association Neurorestoratology (IANR) completed first set guidelines governing application neurorestoration in 2011. IANR and (CANR) collaborated propose current version "Clinical Therapy Guidelines Neurorestoration (IANR/CANR 2017)". council...
BACKGROUND:The aims of this study were to investigate the incidence and risk factors for development bone metastases prognosis in women with cancer uterine cervix using database analysis. MATERIAL AND METHODS:The National Cancer Institute (NCI) Surveillance, Epidemiology, End Results (SEER) was analyzed survival rates diagnosed cervical United States between 2010–2015. Multivariate logistic regression analysis identified metastases. Kaplan-Meier estimated overall survival. Proportional...
International standards for stem cell treatment of neurological disorders have not yet been established. In particular, specific quantitative methods adopted to assess the effectiveness treatment. The aim this study is evaluate functional changes detectable by conventional neurophysiologic in an injured spinal cord during therapy. Twenty adult patients with chronic injury at C4–C8 level were examined somatosensory evoked potentials (SEPs) and motor (MEPs) methods, first time prior then...
We performed proteome mapping (PM), cataloging, and bioinformation analysis of protein lysates human neural (CD133 + ) progenitor stem cells (NPSCs) isolated from the olfactory sheath a nose, multipotent mesenchymal (CD29 , CD44 CD73 CD90 CD34 - stromal (MMSCs) bone marrow, tumor (TSCs) U87 glioblastoma (GB) cell line. identified 1,664 proteins in examined (SCs), 1,052 (63.2%) which are identical NPSCs TSCs 607 (36.47%) MMSCs TSCs. Other GB oncospecific or carcinogenesis associated. The...
To evaluate the short and long-term effects of complex cell therapy 202 cases spinal cord injury (SCI).The main arm included SCI control 20 cases. For hematopoietic stem cells (HSCs) progenitor (PCs) were mobilized to peripheral blood by 8 subcutaneous injections granulocyte colony-stimulating factor (G-CSF) for 4 d are harvested at day 5. The administered intrathecally every 3 mo a long term (3-5 years) according internal research protocol international medical institute tissue engineering....
Purpose: Based on a large-population analysis, we aimed to estimate the incidence and survival of bone metastases (BM) in initial bladder cancer (BC) patients identify risk prognostic factors BC with BM.Patients methods: Using National Cancer Institute's Surveillance, Epidemiology, End Results (SEER) database, diagnosed between 2010 2014 were retrieved.Multivariate logistic Cox regression analyses employed for BM patients.A Kaplan-Meier analysis log-rank test was used overall difference...
Glioblastoma multiforme is an aggressive malignant brain tumor with terminal consequences. A primary reason for its resistance to treatment associated cancer stem cells (CSCs), of which there are currently no effective ways destroy. It remains unclear what become a target cell migration, the role this process in oncogenesis and lines should be used developing antitumor technologies. Using modern post‑genome technologies, present study investigated migration human vitro, comparative proteomes...
BACKGROUND:Traumatic spinal cord injury (SCI) often results in the deficiency of glia and neurons cystic cavities. These syringomyelic cysts can prevent axonal regeneration sprouting. Details mechanism cyst formation are unknown an effective treatment for overcoming is not available. MATERIAL AND METHODS:Ten adult female Wistar rats underwent contusion SCI modeling resulting formation. A novel method locating was developed employed. MRI safe silver needles were inserted through erector...
Immature hematopoietic progenitors are a constant source for renewal of hemocyte populations and the basic component tissue cell repair apparatus. A unique property these cells internalizing extracellular double-stranded DNA has been previously shown. The leukostimulatory effect demonstrated in our pioneering studies was considered to be due feature this cell. In present research, we have analyzed effects genome reconstructor preparation (DNAgr), DNAmix, human recombinant angiogenin on both...
Time is infinite movement in constant motion. We are glad to see that Neurorestoratology, a new discipline, has grown into rich field involving many global researchers recent years. In this 2019 yearbook of we introduce the most advances and achievements field, including findings on pathogenesis neurological diseases, neurorestorative mechanisms, clinical therapeutic globally. Many patients have benefited from treatments cell therapies, neurostimulation/neuromodulation, brain–computer...
Glioblastoma multiforme is an invasive malignant glial brain tumor with a poor prognosis for patients. The primary reasons that lead to the development of treatment resistance are associated cells infiltrating parenchyma and specific properties stem cells. A crucial research area in medical science search effective agents able act on these targets. Fascaplysin alkaloids possess potent antitumor activity. Modern methods targeted delivery drugs reveal extensive possibilities terms clinical use...
The development of antitumor medication based on autologous stem cells is one the most advanced methods in glioblastoma multiforme (GBM) treatment. However, there are no objective criteria for evaluating effectiveness this cancer (CSCs). One possible criterion could be a change number microglial and their specific location tumor. present study aimed to understand interaction between CSCs an experimental model. C6 glioma were used create model, as they have immunophenotypic characteristics...
Multiform glioblastoma is the most common primary, highly invasive, malignant tumor of central nervous system, with an extremely poor prognosis. The median survival patients following surgical resection, radiation therapy and chemotherapy does not exceed 12-15 months thus, novel approaches for treatment disease are required. phenomenon directed migration stem cells in tissue presents a approach development technologies that facilitate targeted delivery drugs other therapeutic agents to foci....