- Nanoparticle-Based Drug Delivery
- Graphene and Nanomaterials Applications
- Optical Imaging and Spectroscopy Techniques
- Nanoparticles: synthesis and applications
- Photoacoustic and Ultrasonic Imaging
- Carbon Nanotubes in Composites
- Neuroscience and Neural Engineering
- Infrared Thermography in Medicine
- Neurogenesis and neuroplasticity mechanisms
- SARS-CoV-2 and COVID-19 Research
- Functional Brain Connectivity Studies
- Alzheimer's disease research and treatments
- Anesthesia and Neurotoxicity Research
- Nanoplatforms for cancer theranostics
- Neurological Disease Mechanisms and Treatments
- Sleep and related disorders
- Spinal Fractures and Fixation Techniques
- Glioma Diagnosis and Treatment
- Mesenchymal stem cell research
- Spine and Intervertebral Disc Pathology
- Long-Term Effects of COVID-19
- Transcranial Magnetic Stimulation Studies
- Advanced Fluorescence Microscopy Techniques
- Photoreceptor and optogenetics research
- Advanced Chemical Sensor Technologies
Brain Mapping Foundation
2009-2024
BioElectronics (United States)
2017-2024
Loma Linda University
2020-2022
Middle East Institute
2022
NanoBio (United States)
2017-2021
Brain Innovation (Netherlands)
2021
NASA Research Park
2016
Cedars-Sinai Medical Center
2002-2013
Keck Hospital of USC
2010
Viterbo University
2010
Abstract In this research, we demonstrate cell uptake of magneto-electric nanoparticles (MENPs) through nanoelectroporation (NEP) using alternating current (ac)-magnetic field stimulation. Uptake MENPs was confirmed focused-ion-beam assisted transmission electron microscopy (FIB-TEM) and validated by a numerical simulation model. The NEP performed in microglial (MG) brain cells, which are highly sensitive for neuro-viral infection were selected as target nano-neuro-therapeutics. When the...
Abstract Transcranial direct current stimulation (tDCS) is among the rapidly growing experimental approaches to enhance athletic performance. Likewise, novel investigations have recently addressed effects of transcutaneous spinal Direct Current Stimulation (tsDCS) on motor functions such as reduced reaction time. The impact tDCS, and tsDCS might be attributed altered spontaneous neural activity membrane potentials cortical corticomotoneuronal cells, respectively. Given paucity empirical...
Abstract Parkinson’s disease (PD) is amongst the relatively prevalent neurodegenerative disorders with its course of progression classified as prodromal, stage1, 2, 3 and sever conditions. With all shortcomings in clinical setting, it often challenging to identify stage PD severity predict course. Therefore, there appear be an ever-growing need use supervised unsupervised artificial intelligence machine learning methods on paraclinical datasets accurately diagnose PD, In today’s...
Traumatic brain injury (TBI) is an enormous public health problem, with 1.7 million new cases of TBI recorded annually by the Centers for Disease Control. However, has proven to be extremely challenging condition treat. Here, we apply a nanoprodrug strategy in mouse model TBI. The novel contains derivative nonsteroidal anti-inflammatory drug (NSAID) ibuprofen emulsion antioxidant α-tocopherol. derivative, Ibu2TEG, tetra ethylene glycol (TEG) spacer consisting biodegradable ester bonds. bonds...
Pain generator-based lumbar spinal decompression surgery is the backbone of modern spine care. In contrast to traditional image-based medical necessity criteria for surgery, assessing severity neural element encroachment, instability, and deformity, staged management common painful degenerative conditions likely be more durable cost-effective. Targeting validated pain generators can accomplished with simplified procedures associated lower perioperative complications long-term revision rates....
Background: Endoscopically visualized spine surgery has become an essential tool that aids in identifying and treating anatomical pathologies are not well demonstrated by traditional advanced imaging, including MRI. These may be during endoscopic lumbar decompression (ELD) categorized into primary pain generators (PPG). Identifying these PPGs provides crucial information for a successful outcome with ELD forms the basis our proposed personalized care protocol (SpineScreen). Methods:...