- Advanced Wireless Communication Techniques
- Bioinformatics and Genomic Networks
- Gene expression and cancer classification
- Gene Regulatory Network Analysis
- Wireless Communication Networks Research
- RNA modifications and cancer
- Evolution and Genetic Dynamics
- HER2/EGFR in Cancer Research
- Wnt/β-catenin signaling in development and cancer
- Innovation and Socioeconomic Development
- Cancer, Lipids, and Metabolism
- Cancer-related gene regulation
- Peptidase Inhibition and Analysis
- Cancer-related molecular mechanisms research
- Cooperative Communication and Network Coding
- Antioxidant Activity and Oxidative Stress
- Target Tracking and Data Fusion in Sensor Networks
- Error Correcting Code Techniques
- Ion Transport and Channel Regulation
- CRISPR and Genetic Engineering
- Genetic factors in colorectal cancer
- Botanical Studies and Applications
- Lung Cancer Treatments and Mutations
- Fibroblast Growth Factor Research
- Cholesterol and Lipid Metabolism
Centro de Estudios Monetarios y Financieros
2025
Southern Illinois University School of Medicine
2016-2023
Chengdu Technological University
2017-2022
Qingdao University of Technology
2017-2022
Nanjing Tech University
2020
Soochow University
2017
City Of Hope National Medical Center
2015
Tongji University
2014
Kaohsiung Chang Gung Memorial Hospital
2010-2013
Chang Gung University
2010-2013
The dried fruits of Crataegus pinnatifida, a local soft drink material and medical herb, demonstrated antioxidant effect in previous study. present study investigates the anti-inflammatory potential flavonoid contents from fruit C. pinnatifida (CF-Fs). preliminary investigation showed that CF-Fs (0.25−0.75 mg/mL) decreased release PGE2 nitric oxide as induced by lipopolysaccharide (LPS, an endotoxin) macrophage RAW 264.7 cells. vivo assay pretreatment rats with (50−200 mg/kg dosed gavage)...
Abstract Nasopharyngeal carcinoma (NPC) is known for its highly metastatic character. Recent advances in diagnosis and treatment have not improved the high mortality rate that attributable to early metastasis. Although several biomarkers correlate with metastasis prognosis, molecular mechanisms of NPC development progression remain unclear. We demonstrate comprehensively fibulin‐3 down‐regulated NPC. Loss expression significantly correlated advanced tumour lymph node‐metastasis stages,...
Gastric cancer (GC) is a common type of cancer, particularly in China. Numerous studies have demonstrated that circulating microRNAs (miRNAs) potential applications as noninvasive biomarkers for diagnosis and prognosis. Microarray-based serum miRNA profiling was performed on the 12 paired pre- post-operative GC patients to screen differentially expressed miRNAs. Twelve different miRNAs between were identified. Those verified by real-time quantitative polymerase chain reaction 110 samples...
This paper describes control algorithm of minimum energy loss in the aeration process wastewater treatment activated sludge system. The basic equations have been proposed this with dissolved oxygen concentration (DO) and amount discharge (QW) being dual-parameter variables organic matter S microbial X tank state variables. Based on present study optimization treatment, multivariable optimal model restriction factors presented paper. modern theory system analysis are introduced into field...
Two facts distinctively separate exporter dynamics from firm dynamics. One is the strikingly low survival rate of new entrants into export markets. The second that survive less than re-entrants. We argue these two are critical to discipline models because many sources heterogeneity (e.g. fixed costs) do not affect rates when firms time their entry decision optimally. extend a standard model by positing experiment resolve an uncertain component in foreign-market profitability. estimate using...
The dried fruit of Crataegus pinnatifida, a local soft drink material and medical herb, was found to possess potential against oxidative stress. In the preliminary study, antioxidant hot-water extract obtained from C. pinnatifida (CF-H) evaluated in terms its capacity quenching 1,1-diphenyl-2-picrylhydrazyl free radicals (EC50 = 0.118 mg/mL). After content analysis, it that CF-H is mainly composed polyphenols including flavonoids (6.9%), procyanidins (2.2%), (+)-catechin (0.5%),...
BackgroundNasopharyngeal carcinoma (NPC) is known for its high metastatic potential and locoregional recurrence, although the molecular alterations that are driving NPC metastasis remain unclear at this time. This study aimed to examine expression of fibulin-5 in NPC, correlate results with clinicopathological variables survival, investigate role human cell lines. Material MethodsStandard semi-quantitative-RT-PCR, quantitative-RT-PCR, immunoblotting, immunohistochemistry were used mRNA...
The Chloride Channel Accessory (CLCA) protein family was first characterized as regulators of calcium-activated chloride channel (CaCC) currents (ICaCC), but the mechanism has not been fully established. We hypothesized that CLCAs might regulate ICaCC by modulating intracellular calcium levels. In cells stably expressing human CLCA2 or vector, we found imaging moderately enhanced intracellular-store release dramatically increased store-operated entry upon cytosolic depletion. Moreover,...
CLCA2 is a p53-, p63-inducible transmembrane protein that frequently downregulated in breast cancer. It induced during differentiation of human mammary epithelial cells, and its knockdown causes epithelial-to-mesenchymal transition (EMT). To determine how promotes differentiation, we searched for interactors using membrane dihybrid screening. We discovered strong interaction with the cell junctional EVA1 (Epithelial V-like Antigen 1) confirmed it by co-immunoprecipitation. Like CLCA2, type I...
Numerical solution methods for option pricing fall into two broad classes, either the lattice framework or Monte Carlo simulation. simulation is problematic American options, while Binomial and Trinomial approaches have difficulty incorporating stochastic jumps. The probability density at expiration that generated by a typically has different skewness kurtosis than embedded in market prices. can be fitted imposing terminal with right moments, using Johnson system of distributions example,...
Atherosclerosis, a major contributor to cardiovascular disease, remains significant health concern worldwide. While previous research has shown that acid-sensing ion channel 1 (ASIC1) impedes macrophage cholesterol efflux, its precise role in atherogenesis and the underlying mechanisms have remained elusive.
We investigate turbo equalization using an algorithm called probabilistic data association (PDA). first propose a general structure for PDA, which consists of linear interference cancellation step followed by in every iteration. Based on the structure, we show that original PDA belongs to one variation and it is computationally inefficient. then unveil popular soft MMSE (SLMMSE) equalizer can be considered as sweep within generalized PDA. Such connection implies further performance...
We address the severe interference condition with unity frequency re-use factor in each cell and propose a novel distributed receiver for reliable detection of uncoded data transmitted multi-user multi-cell multiple input, output (MIMO) systems. The new algorithm employs probabilistic association (PDA) turbo base-station (BS) cooperations (PDA-TB). From Bayesian point view, we modify original complex PDA detector to incorporate priori probability, which makes applicable processing: soft...
In the past decades, significant progresses have been achieved in genetic engineering of nucleases. Among genetically engineered nucleases, zinc finger transcription activator-like (TAL) effector and CRIPSPR/Cas9 system form a new field gene editing. The editing efficiency or targeting effect off-target are two major determinant factors evaluating usefulness enzyme. Engineering strategies improving these enzymes, particularly minimizing their effects, focus this paper. Examples using enzymes...