A5080881253- Telomeres, Telomerase, and Senescence
- Genetics, Aging, and Longevity in Model Organisms
- Spaceflight effects on biology
- Circadian rhythm and melatonin
- Chromosomal and Genetic Variations
- Erythrocyte Function and Pathophysiology
- RNA and protein synthesis mechanisms
- Blood groups and transfusion
- Bacillus and Francisella bacterial research
- DNA Repair Mechanisms
- Reproductive Biology and Fertility
- Cancer Research and Treatments
- Diet and metabolism studies
- Pluripotent Stem Cells Research
- Plant Molecular Biology Research
- Probiotics and Fermented Foods
- Plant Virus Research Studies
- Protein purification and stability
- Light effects on plants
- RNA Research and Splicing
- Magnetic and Electromagnetic Effects
- Cellular Mechanics and Interactions
- Immunodeficiency and Autoimmune Disorders
- Escherichia coli research studies
- Tree Root and Stability Studies
Institute of Biochemical Physics NM Emanuel
1997-2022
Russian Academy of Sciences
1999-2021
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I.Kulakov of the Ministry of Healthcare of the Russian Federation
2019-2021
Semenov Institute of Chemical Physics
1992-2002
Cardiff University
1999
Ministry of Transportation of Ontario
1976
Gamalei Institute of Epidemiology and Microbiology
1973
Academy of Medical Sciences
1970
It is supposed that the development and aging of multicellular animals humans are controlled by a special form clock mechanism - chronograph. The their interconnected program species lifespan has been selected in evolution each to fit resources its ecological niche. theory based on idea about loss neurons brain hypothetical organelles chronomeres represent themselves small DNA molecules, which amplificates segments chromosomal DNA. A regular mode process chronomere losses provided pacemaker...
A metronomic mechanism for the duration control of ontogenetic cycle periods an animal is proposed. The components proposed system include ventricular brain, planet Earth as a generator signals, and temporal DNA (tDNA) substrate that epigenetically marked to measure elapsed time ontogenesis. generates repetitive signals in form hydrodynamic disturbances cerebrospinal fluid (CSF). effect arises due superposition two processes - near-wall unidirectional flow CSF oscillations movement planet....
According to the redusome hypothesis, aging of an organism is determined by shortening chronomeres (small perichromosomal linear DNA molecules). In this paper, a presumptive role for infradian hormonal rhythms considered. Endogenous are supposed actively interact with those shifts which governed exogenous gravitational lunar rhythm. As result interaction, so-called T-rhythm formed. Peaks T-rhythms used as pacemaker signals keep life-long "clockwork" brain running. The "ticking" clock...
The possibility of using the aggregate-hemagglutination technique for detection Bacillus cereus exo-enterotoxin in foodstuffs and culture media is shown. A 0.004-mug quantity enterotoxin per ml can be detected by this method.
During a cell's lifespan, DNA break formation is common event, associated with many processes, from replication to apoptosis. Most of breaks are readily repaired, but some meant persist in time, such as the chromosome ends, protected by telomeres. Besides them, eukaryotic genomes comprise shorter stretches interstitial telomeric repeats. We assumed that latter may also be time. In zebrafish and mouse embryos, cells containing numerous breakage foci were identified. These not apoptosis or...
SUMMARY A new virobacterial agglutination (VBA) test for the immunodiagnosis of plant viruses is described. The based on Staphylococcus aureus cells by virus particles after treatment with homologous antiserum. occurs within 1–5 min. sensitivity 0·1‐0·4 μg virus/ml and not affected shape particle. use affinity purified antibodies sensitisation S. increases reaction 50‐fold enables detection tobacco mosaic cucumber green mottle at a concentration 2 ng/ml. VBA allows estimation potato X, S, M...
The possibility of using the aggregate-hemagglutination technique for detection Bacillus cereus exo-enterotoxin in foodstuffs and culture media is shown. A 0.004-μg quantity enterotoxin per ml can be detected by this method.