A5001052637- Saffron Plant Research Studies
- Phytochemical and Pharmacological Studies
- Flavonoids in Medical Research
- Rabbits: Nutrition, Reproduction, Health
- Lipoproteins and Cardiovascular Health
- Neurological Disorders and Treatments
- Phytochemistry and biological activities of Ficus species
- Pharmacological Effects of Medicinal Plants
- Cardiovascular Disease and Adiposity
- Neurological Disease Mechanisms and Treatments
Universiti Teknologi MARA
2020-2024
Hospital Sungai Buloh
2024
Previous research has shown that natural medications pose health risks, especially in subjects with comorbidities. This study aimed to evaluate the safety of saffron ethanolic extract (SEE) administration early and established atherosclerotic rabbits. Rabbits were given a high-cholesterol diet (HCD) for 4 8 weeks induce atherosclerosis respectively, then they treated 50 100 mg/kg/day SEE. The body weight animals was recorded. Blood samples collected at baseline, pre-treatment, post-treatment...
Background: Various methods were used to induce atherosclerosis in rabbits. One of the most common is high-cholesterol diet (HCD) feeding. However, exact amount and duration HCD feeding early established New Zealand white rabbits (NZWR) continue be debated among researchers. Therefore, this study aims evaluate effectiveness 1% inducing lesions NZWR. Methods: A total 50 g/kg/day was fed three four months old male weighing 1.8 2.0 kg for eight weeks respectively. The body weight lipid profile...
Abstract Crocus sativus L. or saffron has been shown to have anti-atherogenic effects. However, its effects on key events in atherogenesis such as endothelial activation and monocyte-endothelial cell binding lipolysaccharides (LPS)-stimulated vitro model not extensively studied. Objectives To investigate the of bioactive derivative crocin gene protein expressions biomarkers LPS stimulated human coronary artery cells (HCAECs). Methodology HCAECs were incubated with different concentrations...