A5034414462- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Radical Photochemical Reactions
- Catalytic C–H Functionalization Methods
- Sulfur-Based Synthesis Techniques
- Crystallography and molecular interactions
- Metal-Organic Frameworks: Synthesis and Applications
- Catalytic Cross-Coupling Reactions
- Chemical Synthesis and Reactions
- Nanomaterials for catalytic reactions
- Asymmetric Hydrogenation and Catalysis
- Oxidative Organic Chemistry Reactions
- Congenital Heart Disease Studies
- Cardiac Structural Anomalies and Repair
- Aortic Disease and Treatment Approaches
- Lanthanide and Transition Metal Complexes
- Innovative Microfluidic and Catalytic Techniques Innovation
- Atherosclerosis and Cardiovascular Diseases
- Cardiovascular Disease and Adiposity
- Metal complexes synthesis and properties
- Infectious Aortic and Vascular Conditions
- CO2 Reduction Techniques and Catalysts
- Synthesis and Characterization of Heterocyclic Compounds
- Aortic aneurysm repair treatments
- Nanocluster Synthesis and Applications
Yancheng Teachers University
2021-2025
Analysis and Testing Centre
2021-2025
Soochow University
2018-2023
South China University of Technology
2020-2023
Guangzhou Medical University
2020-2023
Guangzhou First People's Hospital
2020-2023
University of Colorado Boulder
2023
Hunan University of Science and Engineering
2023
Shihezi University
2023
Keio University
2023
One hexanuclear Cu(I) cluster of 4,6-dimethylpyrimidine-2-thiolate efficiently catalyzes the dehydrogenative cross-coupling secondary and primary alcohols to α-alkylated ketones with high selectivity. This transformation proceeds through a one-pot sequence dehydrogenation alcohols, condensation aldehydes ketones, hydrogenation resulting α,β-unsaturated generate ketones. catalytic system also displays activity for annulation reaction γ-amino- 2-aminobenzyl yield pyridines quinolines, respectively.
Visible-light-driven, intramolecular C(sp2)–H thiolation has been achieved without addition of a photosensitizer, metal catalyst, or base. This reaction induces the cyclization thiobenzanilides to benzothiazoles. The substrate absorbs visible light, and its excited state undergoes reverse hydrogen-atom transfer (RHAT) with 2,2,6,6-tetramethylpiperidine N-oxyl form sulfur radical. radical benzene ring gives an aryl radical, which then rearomatizes benzothiazole via RHAT.
Acyl radicals have been generated from α-keto acids using inexpensive and commercially available 2-chloro-thioxanthen-9-one as the photoredox catalyst under visible light illumination. These reactive species added to olefins or coupled with aryl halides via a bipyridyl-stabilized Ni(II) catalyst, enabling easy access diverse range of ketones. This reliable, atom-economical, eco-friendly protocol is compatible wide functional groups.
Abstract Diethyl 2,6‐dimethyl‐1,4‐dihydropyridine‐3,5‐dicarboxylate (HEH) has been utilized as a visible‐light photoredox catalyst for the cross coupling of arylhalides and arylsulfinates without transition metal, sacrificial agent, mediator. This method is compatible with various functional groups provides diaryl sulfones in good to high yields. Mechanistic studies indicate that this reaction undergoes stepwise light irradiation HE − , single electron transfer (SET) donor–acceptor complex...
An efficient method for visible-light-initiated, nickel-catalyzed Sonogashira C(sp)–C(sp2) coupling has been developed via an energy-transfer mode. Thioxanthen-9-one as a photosensitizer could significantly accelerate the arylation of alkynes with wide range (hetero)aryl halides in high yields. The cross-coupling reaction undergoes stepwise oxidative addition arylhalide to nickel(0), transmetalation resulting aryl–Ni(II) halide species Zn(II) acetylide into species, energy transfer from...
The nickel-catalyzed esterification of carboxylic acids with aryl bromides using thioxanthen-9-one as a photosensitizer provided esters excellent yields.
An efficient method has been developed for photocatalytic P(O)–C(sp2) coupling of (hetero)aryl halides with H-phosphine oxides or H-phosphites under the irradiation visible light sunlight. The thioxanthen-9-one/nickel dual catalysis mediates this phosphonylation to give arylphosphine and arylphosphonates in moderate excellent yields. This transformation is widely tolerant a range functional groups proceeds efficiently on gram scale.
Notwithstanding some progress in nickel-catalyzed etherification of alkanols and arylhalides, the ability such a Ni-catalyzed transformation employing phenols to diaryl ethers is unsuccessful due phenolates with much lower reduction potentials, which suppress oxidation nickel(II) intermediates into requisite Ni(III) species. We herein report visible-light-initiated, O-arylation arylhalides using t-BuNH(i-Pr) as base thioxanthen-9-one photosensitizer under visible light. This photocoupling...
Photoredox catalysis has recently emerged as a powerful synthetic tool for making variety of carbon‐carbon and carbon‐heteroatom bonds. The development esterification reactions induced by light is an atom economical energy efficient alternative to traditional methods the synthesis esters, with benefits including mild reaction conditions, high chemical yields, wide functional group tolerance. This review summarizes recent progress made in this green methodology, mechanisms action, substrate...
Abstract Reactions of three tetrazole containing carboxylic acid ligands, namely, Hpztza, Htzpya, and Hpytza [Hpztza = 5‐(2‐pyrazinyl)tetrazole‐2‐acetic acid, Htzpya 3‐(5‐tetrazolyl)pyridine‐1‐acetic 5‐(3‐pyridyl)tetrazole‐2‐acetic acid] with NdCl 3 · 6H 2 O under hydrothermal conditions, afforded the complexes [Nd(pztza) (H O) 6 ] pztza 3H ( 1 ), [Nd (tzpya) 12 ]Cl 4 2H [Nd(pytza) Cl(H ). The compounds were structurally characterized by elemental analysis, IR spectroscopy single‐crystal...
We have developed a catalyst-free visible-light-driven C(sp2)-H arylation of unprotected phenols with arylbromides to give 2-arylated phenols. This reaction proceeds through the excitation an electron donor-acceptor complex between phenolate and arylbromide, transfer, debrominative C(sp2)-C(sp2) coupling.
Thoracic aortic dissection (TAD) is a life-threatening disease caused by an intimal tear in the aorta. The histological characteristics differ significantly between area (TA) and distant area. Previous studies have emphasized that certain specific genes tend to cluster at TA. Obtaining thorough understanding of precise molecular signatures near TA will assist discovering therapeutic strategies for TAD.We performed paired comparison pathological patterns with remote (RA). We used Tomo-seq,...
Abstract Organic transformations using carbonyl‐photoredox/metal dual catalysis have attracted much attention in recent years. Abundant and inexpensive carbonyl photosensitizers effectively serve as single electron, energy or hydrogen atom transfer agents to induce metal‐catalyzed cross‐coupling dicarbofunctionalization of olefins. This review covers literature reports photocatalytic coupling reactions from 2020 mid‐2023, with a focus on C−C (C(sp 3 )−C(sp ), C(sp 2 )−C(sp)) C‐heteroatom...
Photoredox/metal dual catalysis is a versatile tandem methodology to construct carbon–carbon and carbon–heteroatom bonds. The focus of this short review the application technology C(sp3)–C(sp3), C(sp3)–C(sp2), C(sp2)–C(sp2), C(sp2)–O, C(sp3)–O bond formation induced by readily available inexpensive carbonyl complexes as single electron transfer agents, photosensitizers, or hydrogen atom agents. 1 Introduction 2 Homocoupling Aryl Halides 3 Functionalization C(sp3)–H Bonds 3.1 Dehydrogenation...
Earth-abundant copper(I) coordination complexes of an imine-phosphine and a diimine have been developed as visible-light photocatalysts. Reaction [Cu(MeCN)4]BF4 with hetero-bidentate phosphinopyrazole (phpz) ligand R1R2C3HN2PPh3 (R1 = R2 H (1a); R1 H, Me (1b); Ph (1c); (1d)) 2,9-dimethyl-1,10-phenanthroline (dmp) gave four heteroleptic bis-chelate Cu(I) [Cu(dmp)(R1R2C3HN2PPh3)]BF4 (2a); (2b); (2c); (2d)) distorted tetrahedral geometries. Complexes 2a-2d exhibited broad absorption in the...
An inexpensive thioxanthen-9-one as a triplet photosensitizer could significantly accelerate this Ni-catalyzed amination of aniline with aryl halides, providing various diarylamines good yields at room temperature.
Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia, and it significantly increases risk of cardiovascular complications morbidity, even with appropriate treatment. Tissue remodeling has been a significant topic, while its systematic transcriptional signature remains unclear in AF. Our study aims to systematically investigate molecular characteristics AF at cellular-level. We conducted single-nuclei RNA-sequencig (snRNA-seq) analysis using nuclei isolated from left atrial...
A unique carbon-based AuAg alloy nanocomposite catalyst was prepared from the heterometallic [Au<sub>4</sub>Ag<sub>4</sub>] cluster for efficient oxidative coupling of anilines.
Abstract Sodium tert-butoxide promotes the efficient etherification of alcohols with aryl bromides at room temperature. This simple procedure has a broad substrate scope, providing practical pathway to alkyl ethers in good yields without addition any transition metal species.
To evaluate the efficacy of hybrid transthoracic periventricular device closure ventricular septal defects (VSDs) in a single center.All patients who underwent VSDs between January 2018 and December 2019 were retrospectively analyzed. The preoperative, operative postoperative findings clinical follow-ups reviewed.A total 59 procedure. Transesophageal echocardiographic guidance was used all procedures. procedure successful 57 procedures (97%). two changed to openheart surgery during same...