A5103752571- Asphalt Pavement Performance Evaluation
- Phase Change Materials Research
- Polymer composites and self-healing
- Craniofacial Disorders and Treatments
- Infrastructure Maintenance and Monitoring
- Cleft Lip and Palate Research
- dental development and anomalies
- Skin Protection and Aging
- Smart Materials for Construction
- Adsorption and Cooling Systems
- Vehicle Routing Optimization Methods
- Advanced Algorithms and Applications
- Fibroblast Growth Factor Research
- Aerodynamics and Fluid Dynamics Research
- Epoxy Resin Curing Processes
- Innovative concrete reinforcement materials
- Hypertrophic osteoarthropathy and related conditions
- Metaheuristic Optimization Algorithms Research
- Forest ecology and management
- Bioenergy crop production and management
- Connective tissue disorders research
- Advanced Battery Technologies Research
- Urban Stormwater Management Solutions
- Optimization and Packing Problems
- Selenium in Biological Systems
Xi’an University of Posts and Telecommunications
2019-2025
Qingdao University
2024
Central China Normal University
2023
Northeast Forestry University
2019-2021
Ludong University
2020-2021
Chang'an University
2014-2018
Jangan University
2015
Icahn School of Medicine at Mount Sinai
2006-2014
Genistein, the most abundant isoflavone of soy derived phytoestrogen compounds, is a potent antioxidant and inhibitor tyrosine kinase. We previously reported antiphotocarcinogenic effects genistein in SKH-1 murine skin, including its capacity for scavenging reactive oxygen species, inhibiting photodynamic DNA damage downregulating UVB(ultra violet B)-induced signal transduction cascades carcinogenesis. In this study we elucidate genistein's photoprotective efficacy within context full...
Abstract Background Apert syndrome is characterized by craniosynostosis and limb abnormalities primarily caused FGFR2 +/P253R +/S252W mutations. The former mutation present in approximately one third whereas the latter two-thirds of patients with this condition. We previously reported an inbred transgenic mouse model Fgfr2 on C57BL/6J background for syndrome. Here we a Fgfr2+/P253R mutation. Results generated +/ P253R mice same C56BL/6J genetic analyzed their skeletal abnormalities. 3D...
Previous research has shown that composite shape-stabilized phase change material (CPCM) a remarkable capacity for thermal storage and stabilization, it can be directly applied to highway construction without leakage. However, recent studies on temperature changing behaviors of CPCM asphalt mixture cannot intuitively reflect the thermoregulation mechanism efficiency mixture. The objective this paper is determine specific heat mixtures mixed with using exchange system data acquisition system....
Beare-Stevenson cutis gyrata syndrome (BSS) is a human genetic disorder characterized by skin and skull abnormalities. BSS caused mutations in the FGF receptor 2 (FGFR2), but molecular mechanisms that induce abnormalities are unclear. We developed mouse model of harboring FGFR2 Y394C mutation identified p38 MAPK as an important signaling pathway mediating these Fgfr2+/Y394C mice exhibited epidermal hyperplasia premature closure cranial sutures (craniosynostosis) due to abnormal cell...
As a novel logistics transportation mode, the passenger and freight integration model has garnered significant attention in recent years. This study focuses on collaborative delivery route planning for rural public buses express vehicles, exploring its application within context of integration. For pickup routing problem with time windows under demand uncertainty, we first developed traditional aimed at minimizing total costs. Subsequently, considering co-transportation between courier...
Apert syndrome is a congenital disorder characterized by severe skull malformations and caused one of two missense mutations, S252W P253R, on fibroblast growth factor receptor 2 (FGFR2). The molecular bases underlying differential phenotypes are still poorly understood it unclear why cleft palate more frequent in patients carrying the mutation. Taking advantage mouse models, we performed novel combination morphometric, histological immunohistochemical analyses to precisely quantify distinct...
The objective of this investigation is to prepare the shape memory hydrogenated epoxy resin used for asphalt mixtures (SM-HEP-AM) and study its properties. (SM-HEP) prepared using bisphenol A (AL-3040), polypropylene glycol diglycidylether diacrylate (JH-230), isophorone diamine (IPDA). formulations SM-HEP-AM are obtained by linearly fitted method. thermo-mechanical property, molecular structure, shape-memory performance studied. glass-transition temperature (Tg) determined differential...
This study evaluates the effects of a combined rice-crayfish farming model and compares this with traditional paddy fields. The focus is on soil aggregate characteristics, organic matter content, also distribution aggregates. research was conducted in Qianjiang, Hubei Province. surface samples were collected from two types arable land: fields (WR) (CR). We performed an analysis content. Results reveal that majority aggregates exceed 2 mm size (≥74.94%). integrated significantly enhances...
Apert syndrome (AS), the most severe form craniosynostosis, is characterized by premature fusion of coronal sutures. Approximately 70% AS patients carry S252W gain-of-function mutation in FGFR2. Besides cranial phenotype, brain dysmorphologies are present and not seen other FGFR2-asociated such as Crouzon (CS). Here, we hypothesized that leads only to overstimulation FGFR2 downstream pathway, but likewise induces novel pathological signaling. First, profiled global gene expression wild-type...