- Cardiac Arrest and Resuscitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Mechanical Circulatory Support Devices
- Sepsis Diagnosis and Treatment
- Dysphagia Assessment and Management
- Streptococcal Infections and Treatments
- Electrolyte and hormonal disorders
- Acute Kidney Injury Research
- Cerebrospinal fluid and hydrocephalus
- Cardiac Structural Anomalies and Repair
- Neurological Complications and Syndromes
- Pharmacological Effects and Toxicity Studies
- Tracheal and airway disorders
- Thermal Regulation in Medicine
- Esophageal and GI Pathology
- Child Nutrition and Feeding Issues
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Climate Change and Health Impacts
- Moyamoya disease diagnosis and treatment
- Restraint-Related Deaths
- Teratomas and Epidermoid Cysts
- Antibiotics Pharmacokinetics and Efficacy
- Poisoning and overdose treatments
- Spinal Dysraphism and Malformations
- Radiation Dose and Imaging
Toho University
2013-2025
Toho University Omori Medical Center
2013-2025
Toho University Medical Center Sakura Hospital
2023-2025
University Medical Center
2012-2022
University Hospital and Clinics
2012-2022
Long-term administration of proton pump inhibitors (PPIs) has been increasingly recognized to cause hypomagnesemia due impaired magnesium absorption in both the small and large intestines. Hypomagnesemia can lead various electrolyte imbalances, including hypokalemia, hypocalcemia, and, less commonly, hyponatremia hypophosphatemia. Measuring serum levels is essential for identifying underlying patients receiving PPIs with unexplained abnormalities. Currently, no standardized treatment exists...
The insertion of foreign objects into the genitals for sexual pleasure has been reported in a certain number cases by both men and women. Common include household items such as batteries, pens, thermometers, but unexpected substances glue jelly foods have also identified. These acts can cause health hazards, diagnosis is often delayed, especially when patients hide fact due to shame. This report presents case 54-year-old male who developed bilateral epididymitis after injecting urethra...
Rapid assessment of severity is crucial for timely intervention and improved patient outcomes in heatstroke (HS). However, existing biomarkers are limited their accuracy accessibility ER settings. A prospective pilot study was conducted to assess urinary liver fatty acid-binding protein (L-FABP) levels using a point-of-care testing (POCT) upon HS. Severity estimated initial Sequential Organ Failure Assessment (SOFA) scores, were measured modified Rankin Scale (mRS) scores. In 78 severe HS...
Traumatic brain injury (TBI) is widely known to cause dynamic changes in cerebral blood flow (CBF). Ischemia a common and deleterious secondary following TBI. Detecting early ischemia TBI patients important prevent further advancement deterioration of the tissue. The purpose this study was clarify circulatory disturbance during phase whether it can be used predict patient outcome. A total 90 with underwent xenon-computed tomography (Xe-CT) subsequently perfusion CT evaluate circulation on...
Abstract The objective of this single-center retrospective cohort study was to investigate the relationship between blood transfusion and persistent inflammation, immunosuppression, catabolism syndrome (PIICS). conducted at Critical Care Center Toho University Omori Medical Center, Japan. We included 391 patients in PIICS group (hospitalization for > 15 days, C-reactive protein 3.0 mg/dL or albumin < lymph 800/μL on day 14) 762 non-PIICS days not meeting criteria). performed univariate...
Subarachnoid hemorrhage (SAH) causes dynamic changes in cerebral blood flow (CBF), and results delayed ischemia due to vasospasm, early perfusion deficits before vasospasm (CVS). The present study examined the severity of circulatory disturbance during phase CVS whether it can be used predict patient outcome. A total 94 patients with SAH underwent simultaneous xenon computed tomography (CT) CT evaluate circulation on Days 1-3. Cerebral (CBF) was measured using mean transit time (MTT)...
Soft tissue eosinophilic granulomatosis (Kimura's disease) is an granuloma with a proliferation of lymphoid follicles in the subcutaneous soft tissue. Although no established treatment exists, it considered disease good prognosis. On other hand, bacteremia caused by group G hemolytic streptococcus (GGS) said to be chronic local lymph abnormalities and likely recur. We present case 41-year-old Japanese man. He had history for Kimura's sepsis due came our hospital chief complaint fever. His...
High-pressure injection injuries, caused by forcefully injecting liquids or gases into the body, present significant challenges in diagnosis and treatment. Complications such as infection compartment syndrome can occur, leading to various outcomes, including possibility of amputation. Treatment approaches vary, with some cases undergoing surgery others opting for conservative methods. However, due rarity this injury, clear treatment guidelines are lacking. Consequently, there is insufficient...
This study's aim is to measure liver-type fatty acid-binding protein (L-FABP) levels in urine using a rapid semiquantitative assay kit the emergency department and investigate whether onset of acute kidney injury (AKI) after hospitalization can be predicted.This was prospective observation study. Patients transferred critical care center were divided into two groups: urinary L-FABP negative positive groups. The status severity AKI evaluated for respective patients based on Kidney Disease:...
Nutmeg is a commonly used spice that contains myristicin, compound with anticholinergic and psychoactive properties. Excessive consumption can lead to toxicity, causing psychiatric symptoms such as tachycardia, dizziness, dry mouth, tremors, nausea. poisoning rare not widely recognized. This report describes the case of 33-year-old woman who accidentally ingested toxic amount nutmeg while cooking. She presented anxiety was subsequently diagnosed poisoning. Blood tests revealed electrolyte...
Background & aimsEarly provision of a high-protein nutrition improves the prognosis patients in intensive care units (ICUs). However, high protein intake increases blood urea nitrogen (BUN). No study has compared outcomes according to intake, and clinical significance changes BUN (ΔBUN) ICU is unclear. Here, we investigated association with assessed ΔBUN.MethodsThis was single-center retrospective cohort study. Between 1 January 2016 30 September 2019, 295 received enteral for at least 3...
Abstract If meningitis is suspected, head computed tomography performed before cerebrospinal fluid collection. Crown dens syndrome can be diagnosed using simultaneous CT scans of the and neck. Thus, unnecessary CSF tap test avoided.
Background Predicting the prognosis of intensive care unit (ICU) patients is crucial because it may lead to patient stratification that would in turn help appropriately distributing limited medical resources. This study, therefore, aimed investigate use urinary liver-type fatty acid-binding protein (L-FABP) semi-quantitative kit rapidly predicting admitted ICU.Methods We conducted a single-center, prospective, observational study wherein 100 consecutive ICU with an indwelling bladder...
Background: Tongue pressure values in patients with dysphagia are reported to be significantly lower than those healthy controls. The aim of this study was measure the maximum tongue (MTP) after extubation order assess presence post-extubation for safe initiation oral intake elderly patients. Methods: Data from 90 who were extubated mechanical ventilation under tracheal intubation collected retrospectively. divided into two groups as follows: normal group (those did not develop aspiration...
Patients with dementia may forget to take their oral medications or accidentally too much. Furthermore, there are cases where people lick the medicine without recognizing it as a ingest it. An 88-year-old woman history of insomnia presented hospital, complaining her weakness and mild loss consciousness. Although blood tests, imaging studies, neurological findings were unremarkable, we noticed that tongue was blue determined she had mistakenly taken flunitrazepam. This accidental ingestion...
<title>Abstract</title> Rapid assessment of severity is crucial for timely intervention and improved patient outcomes in heatstroke (HS). However, existing biomarkers are limited their accuracy accessibility prehospital / ER settings. A prospective study was conducted to assess urinary liver fatty acid-binding protein (L-FABP) levels using a point-of-care testing upon HS. Pathophysiological estimated initial Sequential Organ Failure Assessment (SOFA) scores, were measured modified Rankin...
Acute glaucoma attacks cause a sudden increase in intraocular pressure. In addition to ocular symptoms such as redness, visual impairment, and eye pain, it also presents with headache vomiting. It is diagnosed using slit lamp microscope, gonioscope, anterior segment optical coherence tomography. A 72-year-old man visited the emergency room complaining of repeated vomiting throbbing right temporal region. Conjunctival congestion was observed. However, this not considered important at initial...
BACKGROUND Toluene poisoning can occur as a result of occupational exposure in industries such painting, well through misuse, leading to complications neurological symptoms due the accumulation metabolic byproduct hippuric acid and acidosis. However, exact mechanisms remain unclear. Hippuric is not removed by dialysis, so urinary excretion plays central role. Symptomatic treatment, primarily involving fluid replacement, remains standard approach for managing toluene toxicity. Nonetheless,...
Most intracranial lipomas are asymptomatic, but headache is the most common symptom. The pounding score sometimes high. Therefore, it necessary to monitor imaging findings in parallel with treatment of migraine.
Key Clinical Message Multiple neodymium magnets can pinch tissue and cause barotrauma. Be careful if the of penis or foreskin is pinched, as this may necrosis damage to urethra.
Toluene poisoning is diagnosed based on toluene exposure history and the level of hippuric acid in urine. Regular blood urine tests are performed for follow-up. A 54-year-old man collided with a utility pole while driving car was rushed to our hospital complaint loss consciousness. Although trauma minor, suspected presence impaired consciousness, occupation painting job that involves toluene, metabolic acidosis normal anion gap. Urinary urinary liver-type fatty acid-binding protein (L-FABP)...