A5002163682- EEG and Brain-Computer Interfaces
- Botulinum Toxin and Related Neurological Disorders
- Lysosomal Storage Disorders Research
- Glycogen Storage Diseases and Myoclonus
- Balance, Gait, and Falls Prevention
- Parkinson's Disease Mechanisms and Treatments
- Tendon Structure and Treatment
- Lower Extremity Biomechanics and Pathologies
- Orthopedic Surgery and Rehabilitation
- Scoliosis diagnosis and treatment
- Nerve Injury and Rehabilitation
- Multiple Sclerosis Research Studies
- Peripheral Neuropathies and Disorders
- Cerebral Palsy and Movement Disorders
- HIV/AIDS drug development and treatment
- HIV Research and Treatment
- Pharmacological Effects of Natural Compounds
- Peripheral Nerve Disorders
- Ion channel regulation and function
- Diabetic Foot Ulcer Assessment and Management
- Heart Rate Variability and Autonomic Control
- Foot and Ankle Surgery
- Pregnancy and preeclampsia studies
- HIV-related health complications and treatments
- Sports Performance and Training
University of Basilicata
2024-2025
University of Campania "Luigi Vanvitelli"
2018-2025
University of Trieste
2021
Introduction: The “postural control system” acts through biomechanical strategies and functional neuromuscular adaptations to maintain body balance under static dynamic conditions. Postural stability weight distribution can be affected by external sensory inputs, such as different visual stimuli. Little information is available about the influence of receptors on stabilometric plantar pressure parameters. aim this study was analyze variability, correlations, changes in these parameters open-...
Neurofibromatosis type 1 (NF1) is one of the most common genetic tumor predisposition syndrome, caused by mutations in NF1. To date, few genotype-phenotype correlations have been discerned NF1, due to a highly variable clinical presentation. We aimed study molecular spectrum NF1 and monocentric cohort 85 patients (20 relatives, 65 sporadic cases). Clinical data were collected at time mutation analysis reviewed for accuracy this investigation. An internal phenotypic categorization was...
Executive functions (EFs) are neurocognitive processes planning and regulating daily life actions. Performance of two simultaneous tasks, requiring the same cognitive resources, lead to a fatigue. Several studies investigated cognitive-motor task interference during walking, highlighting an increasing risk falls especially in elderly people with neurological diseases. A few instrumentally explored relationship between activation-no-activation EFs (working memory inhibition) spatial-temporal...
Total Ankle Replacement (TAR) could, in theory, partially restore joint sensation and motion, enhancing motor coordination, functional stability, proprioception a affected by osteoarthritis. The aim of this study is to evaluate ankle before after via an instrumental objective assessment. evaluation proprioceptive stability was carried out using the dedicated Delos Postural Proprioceptive System (DPPS). clinical performed administering validated questionnaires, namely American Orthopaedic...
Postural abnormalities in the sagittal plane are common Parkinson’s disease (PD) and increase risk of falls. Previous studies have reported short-term benefit corrective corsets PD patients assessed by clinical instrumental methods, while long-term effects on posture upright standing during walking remain unexplored. Fifteen with postural plane, evaluated via NeuroPostureApp, ten healthy subjects matched for age BMI were 3D motion analysis posture. Then, without K1 Posture Keeper at baseline...
Background: Postural stability and plantar pressure parameters can be assessed by baropodometry; nevertheless, they are often affected low repeatability. The aim of the study was to test accuracy repeatability a novel resistive sensor plate establish most reliable baropodometric parameters. Methods: Accuracy FM12050 BTS-Bioengineering measurements were using different weights in static conditions across three sessions. Subsequently, 20 healthy subjects 30-s stabilometric analysis bipedal...
Postural stability is maintained by the Control System (PCS), consisting of anatomical structures Central Nervous and peripheral receptors, interacting with each other, in order to keep whole-body balance modulating myofascial chains against gravity. The vision one most important receptors for postural control. Previous studies analyzed changes body sway during viewing nearby (VNT) distant (VDT) targets healthy population without considering feet adaptations related weight distribution. Aim...
BACKGROUND: Asymmetrical posture maintained over long training periods may affect phenotypic plasticity, resulting functional to sporting goal but negative the locomotor system. Aim of this study was quantitatively evaluate these long-term effects in competitive boxers.METHODS: Baropodometric analysis used assess 20 boxers and non-sportsmen upright bipedal for 5 s 51.2 with open (OE) closed (CE) eyes.RESULTS: The boxers' group (BOX) showed a larger total foot load (TFL) (p=0.022) on right...
Posture can be evaluated by clinical and instrumental methods. Three-dimensional motion analysis is the gold standard for static dynamic postural assessment. Conventional stereophotogrammetric protocols are used to assess posture of pelvis, hip, knee, ankle, trunk (considered as a single segment) rarely head upper limbs during walking. A few studies also analyzed multi-segmental whole-body kinematics. Aim our study was evaluate sagittal spine walking in healthy subjects 3D using new marker...
During pregnancy, SARS-CoV-2 infection is associated with several adverse outcomes, including an increased risk of pre-eclampsia, preterm delivery, hypertensive disorders, gestational diabetes, and fetal growth restriction related to the development placenta vascular abnormalities. We analyzed human from full-term, uncomplicated pregnancies during first, second, or third trimesters gestation. studied, by immunohistochemistry technique, expression CD34 podoplanin (PDPN) as markers...
This study is the first to quantitatively characterize sagittal spine and whole body posture of patients with late-onset Pompe disease during walking, showing a pathological kinematic pattern defined “man falling backwards.” 3-D-motion analysis, specific marker set (DB-total protocol) introducing new parameters, may be useful for accurate functional evaluation monitoring this rare disease.
Foot drop (FD) is characterized by an inability to lift the foot against gravity because of dorsiflexor muscle weakness. The aim present study report a clinical case acute non-traumatic FD in patients with peroneal intraneural ganglion, after performing scoping review on methodological management this disease. We performed literature and reported 49-year-old man caused ganglion cyst nerve. Out total 201 articles, 3 were suitable for our beyond report. can be managed careful...
Hoverboards are always more popular among children. to them like a game or mean of transport, but they could be used as valid and useful instrument in children’s training programs improve their performance. In this study, we compared the athletic performance two groups 12 A total 24 children aged between 8 11 years followed similar program for five months, first group hoverboard (Hb+ group: Age: Standard Deviation (SD) = 1.15 Mean 9.66; Weight: SD 5.90 32; Height: 7.64 135.08) some time,...
Late Onset Pompe Disease (LOPD) is a rare myopathy characterized by prevailing weakness of trunk and pelvic girdle muscles that causes motor disabilities. Spinal deformities have been reported unclearly on clinical examination. No study quantitatively assessed upright posture defining specific alterations LOPD various phenotype.Identify postural abnormalities in homogeneous group patients using 3D Stereophotogrammetry (St) x-Ray (xR).Seven siblings were recruited. They scales and, posture,...
Integrase strand transfer inhibitors (INSTIs) are a class of antiretroviral therapy (ART) medications with good tolerability profile and high genetic barrier to HIV drug resistance. However, several studies report significant weight gain among persons receiving INSTI-based ART regimens compared other regimens.In-vitro model adipogenesis.We used 3T3-L1 cells investigate the effects nucleoside reverse transcriptase (NRTIs) tenofovir disoproxil fumarate (TDF) alafenamide (TAF), alone or in...
Autophagic vacuolar myopathies (AVMs) are an emerging group of heterogeneous sharing histopathological features on muscle pathology, in which autophagic vacuoles the pathognomonic morphologic hallmarks. Glycogen storage disease type II (GSDII) caused by lysosomal acid α-glucosidase (GAA) deficiency is best-characterised AVM.This study aimed to investigate mutational profiling seven neuromuscular outpatients clinical, myopathological and biochemical findings with AVMs.We applied a diagnostic...