A5056264467- Asthma and respiratory diseases
- Respiratory and Cough-Related Research
- HIV/AIDS drug development and treatment
- HIV-related health complications and treatments
- Respiratory Support and Mechanisms
- Ultrasound in Clinical Applications
- HIV Research and Treatment
- Allergic Rhinitis and Sensitization
- Gut microbiota and health
- Piperaceae Chemical and Biological Studies
- Pneumonia and Respiratory Infections
- Sex and Gender in Healthcare
- SARS-CoV-2 and COVID-19 Research
- Biochemical Analysis and Sensing Techniques
- Clostridium difficile and Clostridium perfringens research
- Pregnancy and preeclampsia studies
- Dermatology and Skin Diseases
- Phonocardiography and Auscultation Techniques
- Respiratory viral infections research
- Long-Term Effects of COVID-19
- Ginger and Zingiberaceae research
- Medicinal Plant Research
- Pleural and Pulmonary Diseases
- Inhalation and Respiratory Drug Delivery
- Neonatal Respiratory Health Research
Santobono Children's Hospital
2024
University of Campania "Luigi Vanvitelli"
2019-2024
Food allergy is common in the Mediterranean, especially concerning lipid transfer proteins (LTPs) allergy. LTPs are widespread plant food allergens fruits, vegetables, nuts, pollen, and latex. Also, prevalent Mediterranean area. They can sensitize via gastrointestinal tract cause a wide range of conditions: from mild reactions, such as oral syndrome, to severe anaphylaxis. LTP adult population well described literature, both prevalence clinical characteristics. However, there poor knowledge...
Dupilumab is a new biological drug approved for the treatment of type 2 inflammatory diseases, such as asthma. fully humanized monoclonal antibody that acts against both interleukin-4 and interleukin-13 receptors. This study evaluated time--dependent effect dupilumab on asthma exacerbations quality life in adolescents with uncontrolled severe asthma.Five suffering from treated were recruited. All subjects 4, 12, 24 weeks after first dose dupilumab. Outcome measures included lung function,...
Integrase strand transfer inhibitors (INSTIs) are a class of antiretroviral therapy (ART) medications with good tolerability profile and high genetic barrier to HIV drug resistance. However, several studies report significant weight gain among persons receiving INSTI-based ART regimens compared other regimens.In-vitro model adipogenesis.We used 3T3-L1 cells investigate the effects nucleoside reverse transcriptase (NRTIs) tenofovir disoproxil fumarate (TDF) alafenamide (TAF), alone or in...
Seasonal allergic rhinitis (SAR) is a common disease of childhood and characterized by type 2 inflammation, bothersome symptoms, impaired quality life (QoL). Intranasal corticosteroids are effective medications in managing SAR. In addition, mometasone furoate nasal spray (MFNS) well-known therapeutic option. However, the literature provided no data about effects MFNS European children with Thus, this study addressed unmet requirement.MFNS was compared to isotonic saline. Both treatments were...
Background: Long COVID affects 8 to 10 % of children. Currently, the COVID-19 fo-llow-up protocols in children include chest auscultation, collection growth parameters, including weight, height and body mass index, execution six-minute walking test, basal spirometry, afterwards, bronchodilation test lung ultrasound. Case Presentation: In this paper, authors describe a case series long followed up for 9 months at Department Pediatrics University Luigi Vanvitelli. The review lite-rature was...
Abstract Background Brain injury in hereditary hemoglobinopathies is commonly attributed to anemia-related relative hypoperfusion terms of impaired oxygen blood supply. Supratentorial and infratentorial vascular watershed regions seem be especially vulnerable, but data are very scarce. Aims We investigated a large beta-thalassemia sample with arterial spin labeling order characterize regional perfusion changes their correlation phenotype anemia severity. Methods performed multicenter...
Background: The concept of atopic march was introduced about 15 years ago to define the temporal progression different allergic conditions, from dermatitis and food allergies in earliest childhood development asthma rhinitis older children. Case Presentation: authors describe a case report young girl who went through stages march. child first showed allergy infancy, and, after-wards, she manifested childhood. Discussion: This timeline reflects march's spatial evolution, beginning with skin...
Background: Children with mild or asymptomatic COVID-19 represent the majority of paediatric cases. Hospitalisation and critical care are required only in a small proportion SARS-CoV-2 positive children who present severe symptoms, like interstitial lung disease. A quarter experience persistent symptoms some months later after being hospitalised, they need to be properly followed up. Case Presentation: The authors describe case report long-COVID 5 years old child, was previously hospitalized...
ABSTRACT Integrase strand transfer inhibitors (INSTI) are a recently available class of antiretroviral therapy (ART) medications with good tolerability profile and high genetic barrier to HIV drug resistance. However, several studies report more significant weight gain among persons receiving INSTI-based ART regimens for initial compared protease (PIs) nucleoside reverse transcriptase (NNRTI)-based regimens. In our experimental setting, we used the in vitro model adipogenesis 3T3-L1 cells...