A5028021748- Thyroid Cancer Diagnosis and Treatment
- Parkinson's Disease Mechanisms and Treatments
- Thyroid and Parathyroid Surgery
- Head and Neck Anomalies
- Advanced Neuroimaging Techniques and Applications
- Lymphatic System and Diseases
- Diagnosis and Treatment of Venous Diseases
- Neurological disorders and treatments
- Electron Spin Resonance Studies
- Spinal Fractures and Fixation Techniques
- Lymphatic Disorders and Treatments
- Solid-state spectroscopy and crystallography
- Functional Brain Connectivity Studies
- Dementia and Cognitive Impairment Research
- Acute Ischemic Stroke Management
- Vascular Malformations and Hemangiomas
- Pelvic and Acetabular Injuries
- Alzheimer's disease research and treatments
- Photochemistry and Electron Transfer Studies
- Balance, Gait, and Falls Prevention
- Radiation Effects and Dosimetry
- Spine and Intervertebral Disc Pathology
- Neuroendocrine Tumor Research Advances
- Obstructive Sleep Apnea Research
- Traumatic Brain Injury and Neurovascular Disturbances
Chang Gung University
2016-2025
Kaohsiung Chang Gung Memorial Hospital
2016-2025
Jen-Ai Hospital
2022-2024
Chang Gung Memorial Hospital
2008-2024
National Sun Yat-sen University
2022-2024
University of Tokyo Hospital
2022
Beth Israel Deaconess Medical Center
2019
Xiamen Chang Gung Hospital
2019
Yuan Ze University
2015-2017
National Taiwan Normal University
2015
Parkinson's disease (PD) is a common neurodegenerative associated with accumulation of misfolding proteins and increased neuroinflammation, which may further impair the glymphatic system. The purpose this study was to utilize diffusion tensor image analysis along perivascular space (DTI-ALPS) evaluate system activity its relationship systemic oxidative stress status in PD patients.Magnetic resonance imaging neuropsychological tests were conducted on 25 patients normal cognition (PDN), mild...
<b>BACKGROUND AND PURPOSE:</b> Unlike conventional functional MR imaging where external sensory/cognitive paradigms are needed to specifically activate different regions of the brain, resting connectivity acquires images in absence cognitive demands (a condition) and detects brain regions, which highly temporally correlated. Therefore, is suited for study development pediatric subjects. This aimed determine temporal spatial patterns rfc healthy subjects between 2 weeks years age....
To evaluate white matter integrity in patients with obstructive sleep apnea (OSA) using diffusion tensor imaging (DTI) and to assess its relationship systemic inflammation.Cross-sectional study.One tertiary medical center research institute.Twenty severe OSA (apnea-hypopnea index [AHI] > 30, 18 men 2 women) 14 healthy volunteers (AHI < 5, 11 3 women).N/A.Patients underwent polysomnography determine the severity of apnea, DTI scanning fiber integrity. Early or late phase changes leukocyte...
Abstract Acute lower respiratory infection is the leading cause of child death in developing countries. Current strategies to reduce this problem include early detection and appropriate treatment. Better diagnostic therapeutic are still needed poor Artificial-intelligence chest X-ray scheme has potential become a screening tool for child. schemes children rare limited single lung disease. We need powerful system as most common diseases children. To address this, we present computer-aided...
Ultrasonography (renamed from the Journal of Korean Society Ultrasound in Medicine January 2014), official English-language journal (KSUM), is an international peer-reviewed academic dedicated to practice, research, technology, and education dealing with medical ultrasound, Aims Scope:Ultrasonography ultrasound.It published four times per year: 1, April July October 1. Original articles, topical reviews, pictorial essays, notable case reports are covering state-of-the-art content. also...
Abstract The electron spin resonance of an x-ray irradiated single crystal potassium dihydrogen arsenate has been examined and a radical which is thought to be AsO4 4- identified. Analysis the spectra for various orientations with respect external magnetic field leads axially symmetric hyperfine interaction tensor in agreement what would expected radical. Semi-empirical LCAO molecular orbital calculations symmetry D 2d trapped tetragonal KH2AsO4 crystals conclusion that odd enters A 1...
Systemic inflammation and white matter (WM) alterations have been noted as effects of Parkinson's disease (PD). This study sought to evaluate WM integrity in PD patients using diffusion tensor imaging (DTI) assess its relationship with systemic inflammation. Sixty-six (23 men 43 women) 67 healthy volunteers (29 38 underwent blood sampling quantify inflammatory markers DTI scans determine fiber integrity. The included leukocyte apoptosis, well cellular serum adhesion molecules, each...
Background For current lymphatico‐venous anastomosis (LVA), the identification of “functional” lymphatic collecting vessels (LCVs) is mainly based on indocyanine green (ICG) lymphography. However, some non‐ICG enhanced LCVs utilized for LVA were found to have visual flow. Objectives Should enhanced, but flow‐positive be considered functional as well? Methods A retrospective study with 56 consecutive lymphedema patients (8 male/48 female) received LVA. observed after ICG injection,...
Systemic inflammation, neurocognitive impairments, and morphologic brain changes are associated with obstructive sleep apnea (OSA). Understanding their longitudinal evolution interactions after surgical treatment provides clues to the pathogenesis of cognitive impairment its reversibility. In present study, we investigate clinical disease severity, systemic deficits, corresponding gray matter volume (GMV) in OSA, modifications following surgery. Twenty-one patients OSA (apnea-hypopnea index,...
Background: Inferior lymphatic vessel (LV) quality was thought to be associated with prolonged lymphedema duration (LD), which can lead unfavorable lymphaticovenous anastomosis (LVA) outcomes. However, increasing evidence supports the use of LVA in treatment advanced lymphedema. Hence, this study aimed determine impact LD on LV and outcomes after patients secondary lower limb Patients Methods: A total 189 who underwent supermicrosurgical were retrospectively reviewed enrolled. The group...
To evaluate the association of circulating cell-free mitochondrial DNA (ccf-mtDNA) levels with severity and treatment outcomes sudden sensorineural hearing loss (SSNHL). Observational prospective study. Tertiary academic medical center. Plasma samples were collected from patients diagnosed SSNHL in morning before steroid treatment, as well healthy controls. A quantitative polymerase chain reaction was used to measure ccf-mtDNA levels, expressed log copy numbers per milliliter. Treatment...
Abstract X-ray irradiation of disodium hydrogen arsenate Na2HAsO4.7H2O has been shown to produce a paramagnetic species exhibiting quartet due hyperfine interaction at the 75As nucleus. The g-tensor and coupling have found be axially symmetric. A theoretical treatment is given which enables experimental observations used evaluate tensor, principal values are = 2031·8 Mc/s B=1581·6 Mc/s. identified as ·AsO3 2- radical anion with symmetry C 3v .
The aim of this study was to evaluate the relationship between cognitive impairment and brain perfusion using arterial spin labelling (ASL) in end-stage renal disease (ESRD) patients undergoing PD.ESRD PD were recruited. Laboratory screening, neuropsychological tests ASL magnetic resonance imaging (MRI) conducted prior after 6 months PD. Age- sex-matched normal subjects without ESRD served as control group. Comparisons regional CBF before or controls performed. Correlations biochemical, data...
The aim of this study was to investigate the effects angiotensin II/ II type I receptor (AT1R) and (AT2R) signaling pathway in esophageal squamous cell carcinoma (ESCC).Immunohistochemistry performed evaluate expression levels AT1R AT2R tissues from 152 surgically resected ESCC patients, those were then correlated with treatment outcomes. II/AT1R/AT2R its biological context investigated vitro vivo.In human samples, overexpression univariately associated inferior overall survival remained...
Systemic inflammation and alterations to regional cerebral blood flow (CBF) have been reported previously in obstructive sleep apnea (OSA). This study utilized arterial spin labelling (ASL) perfusion magnetic resonance imaging (MRI) evaluate CBF OSA patients determine its relationship with systemic inflammation. Twenty male moderate severe [apnea-hypopnea index (AHI) >15] 16 healthy volunteers (AHI <5) were recruited. Early- or late-phase changes leucocyte apoptosis subsets determined by...
Introduction Post-stroke depression (PSD) is a serious mental disorder after ischemic stroke. Early detection important for clinical practice. This research aims to develop machine learning models predict new-onset PSD using real-world data. Methods We collected data stroke patients from multiple medical institutions in Taiwan between 2001 and 2019. developed 61,460 used 15,366 independent test the models’ performance by evaluating their specificities sensitivities. The predicted targets...
Hepatic encephalopathy (HE) is a complex neuropsychiatric syndrome and major complication of liver cirrhosis. Dysmetabolism the brain, related to elevated ammonia levels, interferes with intercortical connectivity cognitive function. For evaluation network efficiency, 'small-world' model can quantify effectiveness information transfer within brain networks. This study aimed use small-world topology investigate abnormalities neuronal among widely distributed regions in patients cirrhosis...