A5090060909- Extracellular vesicles in disease
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Adolescent Sexual and Reproductive Health
- HIV/AIDS Research and Interventions
- Pulmonary Hypertension Research and Treatments
- Global Maternal and Child Health
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Mesenchymal stem cell research
- Primary Care and Health Outcomes
- Occupational and environmental lung diseases
- MicroRNA in disease regulation
- HIV, Drug Use, Sexual Risk
- Poverty, Education, and Child Welfare
- Migration, Identity, and Health
- Health Policy Implementation Science
- Tissue Engineering and Regenerative Medicine
- HIV/AIDS Impact and Responses
- Evaluation and Performance Assessment
- Autophagy in Disease and Therapy
Columbia University
2021-2023
ICAP Global Health
2021
Authorised Association Consortium
2021
University of Pittsburgh
2014-2019
Abstract Mesenchymal stem cells (MSCs) and macrophages are fundamental components of the cell niche function coordinately to regulate haematopoietic self-renewal mobilization. Recent studies indicate that mitophagy healthy mitochondrial critical survival cells, but how these processes regulated in MSCs is unknown. Here we show manage intracellular oxidative stress by targeting depolarized mitochondria plasma membrane via arrestin domain-containing protein 1-mediated microvesicles. The...
Macrophages play a fundamental role in innate immunity and the pathogenesis of silicosis. Phagocytosis silica particles is associated with generation reactive oxygen species (ROS), secretion cytokines, such as TNF, cell death that contribute to silica-induced lung disease. In macrophages, ROS production executed primarily by activation NADPH oxidase (Phox) mitochondrial (mtROS); however, relative contribution unclear, effects on macrophage function fate are unknown. this study, we used...
Retaining women in Option B+ services is crucial for eliminating new pediatric HIV infections. However, there are few studies on factors influencing retention at the district level. This study evaluates associated with two health districts of Cameroon.
Abstract Background Antenatal care (ANC) clinics remain important entry points to HIV for pregnant women living with HIV—including adolescents. Prior knowledge of their status at ANC enrollment is crucial providing services prevention mother-to-child transmission (PMTCT) HIV. We examined known adolescents and in other age groups enrollment. Methods A descriptive study routinely reported PMTCT data from 419 facilities Eswatini, Ethiopia, Mozambique, January through December 2018 was...