Shravan Asthana

ORCID: 0000-0002-1356-3764
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About
Contact & Profiles
Research Areas
  • RNA Research and Splicing
  • Spine and Intervertebral Disc Pathology
  • Head and Neck Surgical Oncology
  • Esophageal Cancer Research and Treatment
  • Sinusitis and nasal conditions
  • Health disparities and outcomes
  • Global Cancer Incidence and Screening
  • Cervical and Thoracic Myelopathy
  • Nasal Surgery and Airway Studies
  • Spinal Fractures and Fixation Techniques
  • RNA regulation and disease
  • Bone Tumor Diagnosis and Treatments
  • Homelessness and Social Issues
  • Migraine and Headache Studies
  • Global Health Care Issues
  • Esophageal and GI Pathology
  • Neurofibromatosis and Schwannoma Cases
  • Olfactory and Sensory Function Studies
  • Families in Therapy and Culture
  • PARP inhibition in cancer therapy
  • RNA modifications and cancer
  • Reconstructive Surgery and Microvascular Techniques
  • Geriatric Care and Nursing Homes
  • Drug-Induced Adverse Reactions
  • Soft tissue tumor case studies

Northwestern University
2022-2025

Pennsylvania State University
2022-2024

University of Pennsylvania
2024

Baylor College of Medicine
2023

University of Tennessee Health Science Center
2023

Sinonasal inverted papilloma (IP) is the most common benign tumor found in nasal cavity and has potential for locally destructive effects malignant transformation [1-3]. Birkenbeuel et al. demonstrate that 565 patients with squamous cell carcinoma of their IP, 5-year overall survival rate was 62% a mean recurrence time 24.3 months [4]. Therefore, follow-up crucial detection preemptive revision resection prior to transformation. While postulated, it not yet been examined how socioeconomic...

10.1002/alr.23535 article EN cc-by-nc-nd International Forum of Allergy & Rhinology 2025-01-19

Objectives: Osteocutaneous free flap reconstruction can be complicated by hardware failure. The present study investigates the frequency and predictors of failure in head neck osteocutaneous reconstruction. Methods: Patients who underwent between years 2014 2022 were identified at our institution. Hardware was defined as infection, screw plate loosening, exposed hardware, migration, deformation, or fracture. Results: We 47 patients met inclusion criteria for this study. Common indications...

10.1097/coc.0000000000001180 article EN American Journal of Clinical Oncology 2025-02-19

Study Design. Scoping review. Objective. The objective of this study was to conduct a scoping review exploring the extent which preference sensitivity has been studied in treatment decisions for lumbar spinal stenosis (LSS), utilizing shared decision-making (SDM) as proxy. Background. Preference-sensitive care involves situations where multiple options exist with significant tradeoffs cost, outcome, recovery time, and quality life. LSS gained research focus preference-sensitive scenario....

10.1097/brs.0000000000004952 article EN Spine 2024-02-19

Abstract Objective To characterize neighborhood‐level area deprivation's association with oropharyngeal carcinoma clinicodemographics, tumor staging, recurrence, and overall survival. Study Design Retrospective study. Setting Single institution academic medical center. Methods Patients diagnosed squamous cell (OPSCC) between 2007 2022 at our were included in this The Area Deprivation Index (ADI) was used to quantify disadvantage based on patients’ primary residence the time of their...

10.1002/oto2.70057 article EN cc-by-nc OTO Open 2024-10-01

There is currently no comprehensive tool that quantifiably measures validated factors of modern technology access in the US for digital inequity impact on esophageal cancer care (EC). To assess influence inequities disparities while accounting traditional social determinants. 15,656 EC patients from 2013-2017 SEER were assessed significant regression trends long-term follow-up, survival, prognosis, and treatment with increasing overall inequity, as measured by Digital Inequity Index (DII)....

10.3390/cancers15235522 article EN Cancers 2023-11-22

Background: Sinonasal inverted papilloma is the most common benign tumor found in nasal cavity and has potential for locally destructive effects malignant transformation. More extensive papillomas are often harder to excise can jeopardize other structures, sites of attachment more difficult fully delineate. In this study, we examine effect patient geographical socioeconomic factors, as assessed by Area Deprivation Index (ADI), a calculation based on domains income, education, employment,...

10.1055/s-0044-1780082 article EN Journal of Neurological Surgery Part B Skull Base 2024-02-01

The role of RNA Binding Motif Protein 8a (RBM8A), an exon junction complex (EJC) component, in neurodevelopmental disorders has been increasingly studied for its crucial regulating multiple levels gene expression. It regulates mRNA splicing, translation, and degradation influences embryonic development. RBM8A protein is expressed both neurons astrocytes, but little known about RBM8A's specific glial fibrillary acid (GFAP)-positive astrocytes. To address the we generated a conditional...

10.3390/cells13060498 article EN cc-by Cells 2024-03-13

Hybrid peripheral nerve sheath tumors (HPNSTs) are classified as benign that consist of at least two tumor subtypes - neurofibroma, schwannoma, or perineurioma the lesion site. While there reports these lesions in head and neck, is no documentation a hypopharynx hybrid neurofibroma-schwannoma literature. This case report describes clinical presentation, treatment, histopathologic features 45-year-old man. The patient presented to clinic with mild dysphagia globus but prior history neck...

10.1016/j.xocr.2024.100598 article EN cc-by-nc-nd Otolaryngology Case Reports 2024-03-29

Study Design: Level 3 retrospective database study. Objective: This study aims to compare work RVU (wRVU), practice expense (peRVU), malpractice (mpRVU), and inflation-adjusted facility price alongside MS-DRG relative weight length of stay (LOS) for cervical spine fusions between 2011 2023. Summary Background Data: Both reimbursement have been studied in various surgical subspecialties; however, little investigation has centered on fusions. To the best our knowledge, this is first...

10.1097/bsd.0000000000001660 article EN Clinical Spine Surgery A Spine Publication 2024-08-28

Study Design: Retrospective database study. Objective: This study aims to quantify and compare mean work RVUs (wRVUs), operative time (OpTime), wRVUs/min in single- multilevel anterior posterior cervical spine fusions performed between 2011 2020. Summary of Background Data: Prior research has demonstrated inconsistencies technical skill, time, surgical difficulty with reimbursement various orthopedic subspecialties. Although trends investigating physician effort have been investigated lumbar...

10.1097/bsd.0000000000001684 article EN Clinical Spine Surgery A Spine Publication 2024-10-31

Key points Racial disparities influence the completion of aspirin (ASA) desensitization and ASA‐exacerbated respiratory disease (AERD) diagnosis age. Public insurance correlates with an official AERD after age 50. Social factors, including race status, impact adherence to ASA desensitization.

10.1002/alr.23485 article EN International Forum of Allergy & Rhinology 2024-11-27

Mucosal contact between the turbinates and septum is implicated as a cause of headache migraine. The prevalence mucosal reported to be low 4%. However, inclusion criteria in that study were restrictive, no data on superior turbinate reported. We sought determine nasal endoscopy its association with

10.1177/01455613241306953 article EN cc-by-nc Ear Nose & Throat Journal 2024-12-12

Abstract Objectives: To develop and implement a novel, comprehensive tool called the Digital Inequity Index (DII) that quantifiably measures modern technology access in US to assess impact of digital inequity on esophageal cancer (EC) care nationwide. Methods: A total of15,656 EC patients from 2013-2017 SEER were assessed for significant regression trends long-term follow-up, survival, prognosis, treatment with increasing overall inequity, as measured by DII. The DII was calculated based 17...

10.21203/rs.3.rs-3280374/v1 preprint EN cc-by Research Square (Research Square) 2023-08-29
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