A5009511861- Skin Protection and Aging
- Phytochemicals and Antioxidant Activities
- Essential Oils and Antimicrobial Activity
- Advancements in Transdermal Drug Delivery
- Phytochemistry Medicinal Plant Applications
- Microencapsulation and Drying Processes
- Agricultural and Food Sciences
- TiO2 Photocatalysis and Solar Cells
- Dermatology and Skin Diseases
- melanin and skin pigmentation
- Phytochemistry and Biological Activities
- Advanced Drug Delivery Systems
- Polysaccharides Composition and Applications
- Bee Products Chemical Analysis
- Polysaccharides and Plant Cell Walls
- Venomous Animal Envenomation and Studies
- Proteoglycans and glycosaminoglycans research
- Proteins in Food Systems
- Herbal Medicine and Trade Cooperation
- Natural Compound Pharmacology Studies
- Iron oxide chemistry and applications
- Pigment Synthesis and Properties
- Ginkgo biloba and Cashew Applications
- Coconut Research and Applications
- Pineapple and bromelain studies
Universidade Federal do Ceará
2015-2023
TiO2 is a common inorganic filter used in sunscreens due to its photoprotective effect on the skin against UV radiation. However, use of this kind material cosmetics limited by inherent photocatalytic activity. It known that coating surface can improve some features. Although, many methodologies for purpose are still laborious and time-consuming. Thus, work reports novel, easy, cheap fast strategy coat particles using sonochemistry approach, aiming decrease activity enhance colloidal...
Sickle cell anaemia (SCA) is the most prevalent monogenic disease in Brazil. In SCA, haemoglobin S (HbS) formed, which modifies red blood morphology. Intravascular haemolysis occurs, free Hb and radicals degrade nitric oxide (NO) release arginase, reduces arginine levels. Because a substrate for NO formation, this decrease leads to reduced (vasodilator) synthesis. SCA treatment uses hydroxyurea (HU) maintain high foetal (HbF) levels HbS avoid haemolytic episodes. To analyse efficacy of...
This work describes the development and characterization of triglyceride-based magnetic nanocomposites for application in hyperthermia controlled drug delivery.The solid lipid (MSLN) constituted by mixtures trilaurin-tricaprylin trilaurin-tricaprin have been successfully obtained emulsification-solvent evaporation method.The developed MSLNs were subjected to an external oscillating field showed significant hyperthermia.The samples exposed frequencies 688 869 kHz causing, respectively, a...
Improving the development of modified release matrix systems strictly depends on selecting an appropriate agent capable controlling drug's release.In this study, Adenanthera pavonina galactomannan was investigated as a potential basis for developing controlled rutin.This extracted, purified and characterized by GPC, NMR FT-IR spectroscopy.The mannose/galactose ratio (M/G) 1.46 calculated relative area from signals anomeric region 1 H-NMR spectrum.The main chain consists β(1→4)-D-mannose...
HIGHLIGHTS CF-Ctn[15-34] shows excellent encapsulation efficiency (93,3%) in PLGA nanoparticles. loaded nanoparticles have good physicochemical characteristics. There is a rapid initial release of the nanoparticles, followed by sustained release. improves antifungal effect against Cryptococcus neoformans.
OF GALACTOMANNAN MICROPARTICLES CONTAINING ALLANTOIN.In this work, the allantoin was encapsulated with galactomannan extruded from Delonyx regia, by spray drying technique.The microparticles obtained were structurally characterized infrared spectroscopy (IR), thermal analysis, scanning electron microscopy (SEM) and controlled release profile evaluated.The results of IR suggested formation polymeric wall microcapsules SEM revealed spherical particles an average size range 2.84 ± 0.41 μm.X-ray...
: Objective: The objective of this work was to evaluate the behavior Acid Violet 43 pigment shampoos and conditioners formulations when applied hair through 10 formulations. Method: were developed, these being 5 conditioners. Among shampoos, 4 pigmented in different concentrations 1 served as control. In same way it done for conditioners, conditioner samples subjected organoleptic physicochemical characterization 15 days, evaluated appearance, color odor, after centrifugation, determination...
Resumo O objetivo desse estudo foi formular e avaliar comprimidos de liberação controlada. Comprimidos controlada teofilina foram preparadas pelo método compressão direta usando dois polímeros como, o HPMC K 100M (polímero hidrofílico) a Goma Guar (Polímero natural), isolado ou em mistura (GG:HPMC 3:1) GG:HPMC 1:3). Os caracterizados através do peso médio, diâmetro, altura, dureza, friabilidade. Todos os resultados estiveram conformidade com limites aceitáveis. ensaio intumescimento...
The binary mixtures of Brij ® surfactant and Pluronic F127 were studied as carriers griseofulvin.The systems 78 (C 18 H 37 E 20 ), 98 35 ) 700 100 prepared in the proportions 10/90, 30/70, 50/50 70/30, respectively.The characterizations carried out by tube inversion, rheology, particle size, theoretical cmcs.The griseofulvin solubilization tests performed at 25 °C micellar solutions 1 wt.% quantified UV/Vis.According to rheological data, presence make F127/Brij 70/30 thermoresponsive...
<!DOCTYPE html> <html> <head> </head> <body> <p style="text-align: justify;"><strong>Objective: </strong>Unfractionated heparin and low molecular weight are the drugs most used today in coagulopathy. Although effective, these have limitations their usage, which aroused interest of scientific community researching other substances with a similar effect. This study aims to analyze anticoagulant activity isolated chemically modified pectin extracted from Caipira melon (<em>Cucumis melo</em>...
Nanoparticle Development: Commercially purchased aqueous LMWH solution (Clexane 100 mg/ml) was dissolved in 5ml diclomethane: PLGA (50:50) and sonicated (Sonifier® Model W-450D Branson) at 50% amplitude for 15 seconds an ice bath forming the first emulsion.Immediately thereafter, a 1.0% PVA added sonication again double emulsion.The suspension allowed to stir 6 hours fully evaporate solvent (dichloromethane).Subsequently, separating filter (Amicon Ultra-15ml) centrifuged min 3000rpm (Figure 1).
: Objective: The present work has as objective to evaluate the influence of drying process granules in stove and fluidized bed, well as, stages compression formation nimesulide drug polymorphism. Method: Two tests, TB02 TB06 were produced same way, from weighing granulation, but during test was dried using while oven dried. X-ray diffraction tests show that, all samples, active remains crystalline. Result: Although both batches drugs 85% release 30 mins coefficient variation values for...
: Background: The treatment of dyschromia can be conducted using dermocosmetics containing depigmenting agents, such as kojic acid. Objectives: This study aimed the development and characterization Carnaúba wax-based micro particles, in order to disseminate acid cosmetic dermatological products. Methods: These elements were developed characterized by electron microscopy spectrophotometry, addition evaluation encapsulation effectiveness release profile. Results: different formulations showed...
, popularly known as 'aroeira-do-sertão', a large tree, with tall trunk. Belonging to the Anacardiaceae family, it occurs in 'caatinga' and dry forests of Brazil, from Ceará states Paraná Mato Grosso do Sul. The present study aimed analyse whitening antioxidant activities aqueous extract leaves Myracrodruon urundeuva (AELMU). Inhibition tyrosinase enzyme, well its copper chelating capacity effect were evaluated. AELMU (at 2000 µg/mL) showed excellent inhibitory action (83.76%) on by ion...