A5081243219- Global Public Health Policies and Epidemiology
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Obesity, Physical Activity, Diet
- Chronic Disease Management Strategies
- Diabetes Management and Education
- Nicotinic Acetylcholine Receptors Study
- Ion channel regulation and function
- Health disparities and outcomes
- Diabetes Management and Research
- Health Promotion and Cardiovascular Prevention
- Photoreceptor and optogenetics research
- Nutritional Studies and Diet
- Child Nutrition and Water Access
- Birth, Development, and Health
- Diabetes and associated disorders
- Food Security and Health in Diverse Populations
- Lipid Membrane Structure and Behavior
- Obesity and Health Practices
- Diabetic Foot Ulcer Assessment and Management
- Blood Pressure and Hypertension Studies
- Tuberculosis Research and Epidemiology
- Health Systems, Economic Evaluations, Quality of Life
- Liver Disease Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- HIV/AIDS Impact and Responses
MRC Laboratory of Molecular Biology
2008-2024
Medical Research Council
1990-2024
University of Cambridge
2015-2024
University of the West Indies
2014-2024
MRC Epidemiology Unit
2015-2024
University of Exeter
2020-2024
Royal Cornwall Hospital
2020-2021
Cambridge School
2019-2021
Addenbrooke's Hospital
2020
University of the West Indies
2019
OBJECTIVE—To estimate the global number of excess deaths due to diabetes in year 2000. RESEARCH DESIGN AND METHODS—We used a computerized generic formal disease model (DisMod II), by World Health Organization assess burden through modeling relationships between incidence, prevalence, and disease-specific mortality. Baseline input data included population structure, age- sex-specific estimates available published relative risk death for people with compared without diabetes. The results were...
Objective: To compare coronary risk factors and disease prevalence among Indians, Pakistanis, Bangladeshis, in all South Asians (these three groups together) with Europeans. Design: Cross sectional survey. Setting: Newcastle upon Tyne. Participants: 259 Indian, 305 Pakistani, 120 Bangladeshi, 825 European men women aged 25-74 years. Main outcome measures: Social economic circumstances, lifestyle, self reported symptoms diseases, blood pressure, electrocardiogram, anthropometric,...
The role of GTP hydrolysis in microtubule dynamics has been reinvestigated using an analogue GTP, guanylyl-(alpha, beta)-methylene-diphosphonate (GMPCPP). This binds to the tubulin exchangeable nucleotide binding site (E-site) with affinity four eightfold lower than and promotes polymerization normal microtubules. rate microtubules GMPCPP-tubulin is very similar that GTP-tubulin. However, contrast polymerized GMPCPP-microtubules do not depolymerize rapidly after isothermal dilution....
Abstract Background Tuberculosis (TB) remains a major cause of mortality in developing countries, and these countries diabetes prevalence is increasing rapidly. Diabetes increases the risk TB. Our aim was to assess potential impact as factor for incident pulmonary tuberculosis, using India an example. Methods We constructed epidemiological model data on tuberculosis incidence, prevalence, population structure, relative associated with diabetes. evaluated contribution made by both difference...
Abstract Background This study was established to enable a comparison of lower extremity amputation incidence rates between different centres around the world. Methods Ten centres, all with populations greater than 200 000, in Japan, Taiwan, Spain, Italy, North America and England collected data on amputations done July 1995 June 1997. Patients were identified from at least two sources (to allow checks ascertainment); denominator based census figures. Results The highest Navajo population...