A5003252781- Anesthesia and Sedative Agents
- Anesthesia and Pain Management
- Cardiac, Anesthesia and Surgical Outcomes
- Airway Management and Intubation Techniques
- Respiratory Support and Mechanisms
- Acute Kidney Injury Research
- Bone Metabolism and Diseases
- Nausea and vomiting management
- Organ Transplantation Techniques and Outcomes
- Tracheal and airway disorders
- Abdominal Surgery and Complications
- Ethics in medical practice
- Hemodynamic Monitoring and Therapy
- NF-κB Signaling Pathways
- Palliative Care and End-of-Life Issues
- Patient Dignity and Privacy
- Anesthesia and Neurotoxicity Research
- Transplantation: Methods and Outcomes
- Atrial Fibrillation Management and Outcomes
- Mechanical Circulatory Support Devices
- Renal Transplantation Outcomes and Treatments
- Pediatric Pain Management Techniques
- Inflammatory mediators and NSAID effects
- Neurological Complications and Syndromes
- Bone health and treatments
Yonsei University
2015-2025
Severance Hospital
2014-2024
Ewha Womans University
2007-2023
Sungae Hospital
2019-2020
Creative Commons
2016-2017
Christie's
2016-2017
Jacobson Holman (United States)
2016
Ewha Womans University Medical Center
2013
Catholic University of Korea
2010
Abstract Many inland waters exhibit complete or partial desiccation, have vanished due to global change, exposing sediments the atmosphere. Yet, data on carbon dioxide (CO 2 ) emissions from these are too scarce upscale for estimates understand their fundamental drivers. Here, we present results of a survey covering 196 dry across diverse ecosystem types and climate zones. We show that CO share drivers constitute substantial fraction cycled by waters. were consistent zones, with local...
Bone diseases such as osteoporosis and periodontitis are induced by excessive osteoclastic activity, which is closely associated with inflammation. Benzydamine (BA) has been used a cytokine-suppressive or non-steroidal anti-inflammatory drug that inhibits the production of pro-inflammatory cytokines prostaglandins. However, its role in osteoclast differentiation function remains unknown. Here, we explored BA regulating elucidated underlying mechanism. inhibited strongly suppressed...
Transurethral resection of bladder tumor (TURBT) is commonly performed in elderly patients and often requires repeated procedures. A high proportion non-procedural time TURBT affects operating room utilization, highlighting the need for a safe efficient anesthesia method. This study aimed to compare remimazolam-based monitored care (MAC) guided by analgesia nociception index (ANI) monitoring inhalation-based general (GA) TURBT, focusing on induction emergence (IAET). Forty-six who underwent...
Abstract Cholesterol sulfate (CS) is an activator of retinoic acid‐related orphan receptor α (RORα). CS treatment or RORα overexpression attenuates osteoclastogenesis in a collagen‐induced arthritis mouse model. However, the mechanism by which and regulate osteoclast differentiation remains largely unknown. Thus, we aimed to investigate role their underlying mechanism. inhibited differentiation, but deficiency did not affect CS‐mediated inhibition osteoclastogenesis. enhanced adenosine...
This study aimed to investigate the association between acute kidney injury (AKI) recovery subtypes and days alive out of hospital within first 3 months (DAOH-90) in patients undergoing lung transplantation. Patients who underwent transplantation from January 2012 December 2021 were retrospectively analyzed stratified into three groups: no-AKI, early AKI (within 7 days), non-early group. occurred 86 (35%) patients, which 40 (16%) achieved recovery, remaining 46 (19%) did not. The median...
Background: During robot-assisted laparoscopic radical prostatectomy (RALP), steep Trendelenburg position and carbon dioxide pneumoperitoneum are inevitable for surgical exposure, both of which can impair cardiopulmonary function.This study was aimed to compare the effects pressure-controlled ventilation with volume guarantee (PCV VG) 1:1 equal ratio (ERV) on oxygenation, respiratory mechanics hemodynamics during RALP.Methods: Eighty patients scheduled RALP were randomly allocated either PCV...
Other SectionsABSTRACTINTRODUCTIONRESULTSDISCUSSIONMATERIALS AND METHODSACKNOWLEDGEMENTSCONFLICTS OF INTERESTFIGURESREFERENCES
Cinchonine (CN) has been known to exert antimalarial, antiplatelet, and antiobesity effects. It was also recently reported inhibit transforming growth factor β-activated kinase 1 (TAK1) protein B (AKT) through binding tumor necrosis receptor-associated 6 (TRAF6). However, its role in bone metabolism remains largely unknown. Here, we showed that CN inhibits osteoclast differentiation with decreased expression of nuclear activated T-cells, cytoplasmic (NFATc1), a key determinant...
Background:The incidence of postoperative nausea and vomiting (PONV) remains high.The effects sufentanil for PONV is not firmly confirmed.The aim this study was to compare the effect sufentanil-and fentanyl-based intravenous patient-controlled analgesia (IV-PCA) on after laparoscopic nephrectomy.Methods: Eighty-six patients were randomly allocated receive either (n =43) or fentanyl =43).IV-PCA prepared using 3 µg/kg 20 µg/kg, ramosetron 0.3 mg, ketorolac 120 mg.The primary outcome during 24...
Abstract Background: Vitrectomy under general anesthesia is considered as a candidate for ambulatory surgery. An anesthetic method with high quality of postoperative recovery should be selected successful We thus compared on the day vitrectomy using Quality Recovery (QoR)-40 questionnaire between propofol total intravenous (propofol group) and desflurane inhalation (desflurane 2 representative methods. Methods: Eighty-four patients (20–80 years old) undergoing elective were randomized into...
Background: Postoperative sore throat (POST) is a frequent complication of tracheal intubation, particularly after surgery in the prone position.We designed this study to validate non-inferiority magnesium sulphate against dexamethasone for prevention POST lumbar spinal surgery.Methods: One hundred and forty-six patients were randomly allocated receive either or dexamethasone.Before anesthetic induction, group (n = 73) received 30 mg/kg followed by 10 mg/kg/h continuous infusion until end...
Even after recovery from acute kidney injury, glomeruli remain vulnerable to further injury by way of interstitial fibrosis. This study is aimed at elucidating the effects post ischemia-reperfusion (I/R) treatment with trimetazidine on progression renal fibrosis as well short- and intermediate-term aspects. Trimetazidine 3 mg/kg or 0.9% saline was given intraperitoneally once upon reperfusion daily thereafter for 5 d 8 w. Renal histologic changes related signaling proteins were assessed....
Purpose: Epidural analgesia has been the preferred analgesic technique after major abdominal surgery.On other hand, combined use of intrathecal morphine (ITM) and intravenous patient controlled (IVPCA) shown to be a viable alternative approach for analgesia.We hypothesized that ITM with IVPCA is as effective thoracic epidural (PC-TEA) respect postoperative pain control conventional open gastrectomy.Materials Methods: Sixty-four patients undergoing gastrectomy due gastric cancer were randomly...
Dual-controlled ventilation (DCV) combines the advantages of volume-controlled (VCV) and pressure-controlled (PCV). Carbon dioxide (CO2) pneumoperitoneum steep Trendelenburg positioning for robot-assisted laparoscopic radical prostatectomy (RALRP) has negative effects on respiratory system. We hypothesized that use autoflow as one type DCV can reduce these during RALRP. Eighty patients undergoing RALRP were randomly assigned to receive VCV or DCV. Arterial oxygen tension (PaO2) primary...