A5087064415- Tuberculosis Research and Epidemiology
- Pneumocystis jirovecii pneumonia detection and treatment
- Pneumonia and Respiratory Infections
- Infectious Diseases and Tuberculosis
- Diagnosis and treatment of tuberculosis
- Immunodeficiency and Autoimmune Disorders
- History and Politics in Latin America
- Child and Adolescent Health
- Health and Lifestyle Studies
- Parasites and Host Interactions
- Pharmacological Effects and Toxicity Studies
- Religious and Theological Studies
- Crime, Illicit Activities, and Governance
- Defense, Military, and Policy Studies
- Attention Deficit Hyperactivity Disorder
- Medical Malpractice and Liability Issues
- European Political History Analysis
- HIV/AIDS Research and Interventions
- Aging, Health, and Disability
- International Relations in Latin America
- Smoking Behavior and Cessation
- Respiratory viral infections research
- Amoebic Infections and Treatments
- HIV/AIDS drug development and treatment
- Parasitic Infections and Diagnostics
Universidad La República
2024
Universidad de la República
2024
Instituto Nacional de Salud del Niño
2006-2018
Harvard Global Health Institute
2018
Harvard University
2013-2018
Universidad Simón Bolívar
2013
Institut de Recherche en Santé, Environnement et Travail
2012
EsSALUD
2007
Brigham and Women's Hospital
2006
OBJECTIVES. The goals were to describe the management of multidrug-resistant tuberculosis among children, examine tolerability second-line antituberculosis agents and report outcomes children treated for in poor urban communities Lima, Peru, a city with high prevalence. METHODS. A retrospective analysis data 38 <15 years age tuberculosis, either documented drug sensitivity testing child's isolate or suspected on basis presence clinical symptoms child household contact was performed....
This detailed case history traces the first 5 years of a psychosocial support group intervention aimed to improve adherence individualized drug regimens for multidrug-resistant tuberculosis (MDR-TB) in Peru. A total eight groups were established metropolitan Lima and two provinces Peru led by teams psychiatrists nurses. The consisted bi-monthly groups, recreational excursions, symbolic celebrations, periodic family workshops. Notably, 285 patients who participated this intervention, only...
In 2012, Peru's National TB Program (NTP) reported approximately 2400 incident cases of tuberculosis (TB) disease in children aged <15 years. burden is concentrated the Lima metropolitan area, particularly poor districts such as El Agustino and La Victoria, where this study was conducted.To identify barriers to treatment childhood tuberculous infection from perspective front-line providers patients' families.We conducted 10 semi-structured focus groups with 53 purposefully sampled primary...
OBJECTIVE: We examined factors associated with in-hospital death among children tuberculosis (TB). hypothesized that a negative response to tuberculin skin testing (TST) would predict decreased survival. METHODS: This retrospective cohort comprised 2392 ages 0 14 years hospitalized TB at Peruvian referral hospital over the 25-year study period. Detailed chart abstraction captured clinical history including contacts, physical examination findings, diagnostic data, treatment regimen, and...
In 2012, Peru's National Tuberculosis Program (NTP) reported that children aged 0-14 years accounted for 7.9% of the country's tuberculosis (TB) incidence. This figure is likely an underestimate due to suboptimal diagnosis childhood TB.To identify barriers TB in Lima, Peru.Using semi-structured guides, moderators conducted in-depth interviews with four NTP administrators and five pulmonologists specializing 10 focus groups 53 primary care providers, community health workers (CHWs), parents...
Globally, >30 000 children fall sick with multidrug-resistant (MDR) tuberculosis every year. Without robust pediatric data, clinical management follows international guidelines that are based on studies in adults and expert opinion. We aimed to identify baseline predictors of death, treatment failure, loss follow-up among MDR disease treated regimens tailored their drug susceptibility test (DST) result or the DST a source case.This retrospective cohort study included all ≤15 years old...
We conducted a case-control study among children in Lima, Peru to identify factors associated with tuberculosis disease. Known close contact someone disease, prior hospitalization, and history of anemia were higher disease rate. Consumption fruits/vegetables ≥5 days/week was lower Isoniazid uptake low known contact.
Background:As most national tuberculosis programmes (NTPs) focus on adult (TB), NTP providers may not appreciate differences in the pathophysiology and presentation of childhood TB.Objectives:This study aimed to identify strengths weaknesses knowledge TB among 326 Lima Ciudad Este—two Peruvian capital's four health districts.Methods:310 providers—103 physicians, 106 nurses, 101 nursing technicians—accepted personal invitations complete self-administered surveys, which included 14 questions...
The aims of the study were to assess in patients with advanced HIV disease receiving antiretroviral therapy (ART) intensification enfuvirtide (i) resistance at virological failure (VF), (ii) impact baseline tropism on immunovirological response, and (iii) HIV-1 DNA evolution during ART. ANRS 130 APOLLO randomized trial evaluated naive standard ART without (control arm) or enfuvirtide. Tropism was determined RNA by V3-loop sequencing interpreted using Geno2Pheno algorithm. At median CD4 cell...
Abstract Background International guidelines recommend monitoring weight as an indicator of therapeutic response in childhood tuberculosis (TB) disease. This recommendation is based on observations adults. In the current study, we evaluated association between change and treatment outcome, accuracy using to predict regimen efficacy, whether successfully treated children achieve catch-up gain. Methods We enrolled for drug-susceptible TB disease (group 1) multidrug-resistant 2) Peru....
We conducted a case–control study to examine associations between parasite infection, including protozoa and tuberculosis (TB) in children Lima, Peru. enrolled 189 matched-pairs. In multivariable conditional logistic regression analyses, Blastocystis hominis infection (rate ratio = 0.30, 95% confidence interval 0.14–0.64, P 0.002) was strongly associated with lower risk of TB. observed statistically significant inverse linear dose-response relationship These findings should be confirmed...
Introducción: El tabaquismo es un problema de salud pública a nivel mundial; actualmente considerado la principal causa muerte evitable en el mundo. uso simultáneo tabaco y marihuana se asocia con mayor riesgo persistencia recaída ambos consumos. En los últimos años ha aumentado sistemas electrónicos administración nicotina jóvenes mundial, debido lo novedoso su uso, gran cantidad sabores noción que son menos nocivos. objetivo este estudio fue conocer prevalencia del consumo tabaco,...
Attention deficit hyperactivity disorder (ADHD) is a neurobehavioural whose essential characteristic persistent pattern of inattention or and impulsiveness. Recent studies into prevalence carried out on the Antioquian population by our group found an overall 15.8%, which confirms ADHD as one most frequent problems in infancy. The cause this still not altogether clear; familial aggregation points towards genetic component. Although to date no model inheritance has been defined, its high rate,...
This paper examines a set of conditions that have allowed the existence and de-velopment praetorianism, absence effective civilian control over military in Venezuela. study is based on analysis theoretical parameters laid out by Domingo Irwin, S.E. Finer, contrast to works U.S. author, Gene Bigler.
Tuberculosis in infants is a clinical case difficult to diagnose by regular testing which often yield negative results; additionally, the source of transmission identify. This work presents one-month old nursing boy presenting irritability, tachypnea, fever, poor gain weight from birth, and hepatomegaly. Additionally, he had maternal history pre-extensively drug- resistant tuberculosis tuberculoid granulomatosis reaction with positive auramine tincture for acid-alcohol bacilli at...
Photo: Yukun ChenThe balance of power in Latin America is shifting. Large, recently thriving countries like Brazil are struggling, hampered by domestic scandals. The economies oil-dependent Venezuela and Ecuador stagnant, while other nations, such as Chile Mexico, seem poised for growth. Amid this turbulence, striving to reposition themselves. World Policy Journal consulted a panel experts help understand what issues defining countries’ changing roles the region.The most pressing problem...
The objective of the study was to determine association between BCG immunization and severe tuberculosis (TB). We performed a retrospective study, including medical records from patients pneumology department at National Children’s Institute in Peru, years 1990-2000. A total 2106 TB cases were reviewed, them 259 (miliary or meningoencephalitic TB). all, 497 did not have history vaccination, 202 had 295 non-severe (OR = 0.05, 95% CI 0.03 0.07). In conclusion, children diagnosed with who been...
El objetivo del estudio fue determinar la asociación entre inmunización con BCG y tuberculosis grave (TB). Se realizó un retrospectivo, se incluyó fichas de pacientes atendidos en el servicio neumología Instituto Nacional Salud Niño Perú, los años 1990-2000. revisaron total 2106 casos TB que había 259 graves (TB miliar o meningoencefalitis por TB). Del total, 497 no tenían antecedente BCG; 202 295 (OR= 0,05; IC 95%= 0,03-0,07). En conclusión, niños diagnóstico han sido inmunizados BCG,...