Over the last century a number of techniques have been developed which allow measurement dielectric properties biological particles in fluid suspension.The majority these are limited by fact that they only provide an average value for collection particles.More recently, with advent microfabrication and Lab-on-a-chip, it has possible to perform spectroscopic experiments on single suspended physiological media.In this paper we review current methods cell spectroscopy.We also discuss...

A surface plasmon resonance (SPR) sensor with two open-ring channels based on a photonic crystal fiber (PCF) is described. The designed to detect low refractive indexes between 1.23 and 1.29 the operation wavelength in mid-infrared region 2550 nm 2900 nm. coupling characteristics sensing properties are numerically analyzed by finite element method. average spectral sensitivity 5500 nm/RIU maximum resolution of 7.69 × 10-6 RIU can be obtained. Our analysis shows that PCF-SPR suitable for detection.

Symmetrical dual D-shape photonic crystal fibers (PCFs) for surface plasmon resonance (SPR) sensing are designed and analyzed by the finite element method (FEM). The performance of sensor is remarkably enhanced directional power coupling between two fibers. We study influence structural parameters on as well relationship wavelengths analyze refractive indexes 1.36 1.41. An average spectral sensitivity 14660 nm/RIU can be achieved in this range corresponding index resolution 6.82 × 10-6 RIU....

The rapid advancement of electronic devices and fabrication technologies has further promoted the field wearables smart textiles. However, most current efforts in textile electronics focus on a single modality cover small area. Here, we have developed tailored, conformable suit (E-TeCS) to perform large-scale, multimodal physiological (temperature, heart rate, respiration) sensing vivo. This platform can be customized for various forms, sizes functions using standard, accessible...

The ultra-thin flexible polyimide neural probe can reduce the glial sheath growth on body while its flexibility minimize micromotion between and brain tissue. To provide sufficient stiffness for penetration purposes, we developed a drawing lithography technology uniform maltose coating to make maltose-coated become stiff microneedle. thicknesses under different temperature corresponding are studied. It has been proven that coated is dissolved by fluids after implantation few seconds....

A surface plasmon resonance (SPR) sensor comprising a photonic crystal fibre (PCF) with an annular analyte channel outside the is described and analysed. The losses of are analysed by finite element method (FEM) boundary condition perfectly matched layer (PML). influence structural parameters on performance investigated based loss spectra fundamental mode. relationship between wavelengths refractive indexes established for ranging from 1.395 to 1.425. An average spectral sensitivity...

To achieve sensing of low refractive indexes (RIs) in the near-infrared region, a novel series-wound structure with dual gold nanowires is designed and photonic crystal fiber (PCF) sensor based on surface plasmon resonance (SPR) investigated. Numerical simulation by finite element method (FEM) reveals that odd mode for y-polarization has better properties due to more prominent shift confinement loss peak. The PCF-SPR can realize broad range detection RIs changing from 1.13 1.35. maximum...

Paper-based lateral flow immunoassays (LFIAs) are cost-effective, portable, and simple methods for detection of diverse analytes, which however only provide qualitative or semiquantitative results lack sufficient sensitivity. A combination LFIA electrochemical detection, namely, immunoassay (eLFIA), enables quantitative analytes with high sensitivity, but the integration external electrodes makes system relatively expensive unstable. Herein, working, counter, reference were prepared directly...

Microfabricated impedance cytometers have been developed to measure the electrical of single biological particles at high speed. A general approach analytically solve electric field distributions for two different designs cytometers: parallel facing electrodes and coplanar electrodes, using Schwarz–Christoffel Mapping method is presented. Compared previous analytical solutions, our derivations are more systematic solutions straightforward. The validated by comparison with numerical...

A novel impedance spectroscopy technique has been developed for high speed single biological particle analysis. microfluidic cytometer is used to measure the of micrometre sized latex particles at across a range frequencies. The setup uses based on maximum length sequence (MLS) analysis, where time-dependent response system measured in time domain and transformed into impulse using fast M-sequence transform (FMT). Finally Fourier (FFT) applied give transfer-function frequency domain. It...

Abstract Detection of volatile organic compounds (VOCs) at parts-per-billion (ppb) level is one the most challenging tasks for miniature gas sensors because high requirement on sensitivity and possible interference from moisture. Herein, first time, we present a novel platform based hybrid photonic cavity with metal-organic framework (MOF) coatings VOCs detection. We have fabricated compact sensor detection limitation ranging 29 to 99 ppb various including styrene, toluene, benzene,...

An asymmetrical birefringence photonic crystal fiber based on a surface plasmon resonance (SPR) sensor designed to detect the low analyte refractive indexes is investigated by novel analysis method. The results show that birefringent method can replace conventional confinement loss pertaining investigation SPR structures. air holes in are arranged square lattice structure and two active plasmonic gold layers deposited inner of left right channels enhance phenomenon. shows broad index...

Abstract Lateral flow immunoassays (LFIA) are widely used for the cost‐effective and rapid detection of diverse analytes. However, traditional LFIA suffers from difficulties in providing quantitative results has low sensitivity. Herein, is combined with electrochemiluminescence (ECL), a leading transduction technique high sensitivity wide dynamic range, to achieve highly sensitive severe acute respiratory syndrome coronavirus nucleocapsid protein (SARS‐CoV‐2 N protein). Ruthenium(II)‐based...

Dielectric spectroscopy is a powerful tool for investigating the dielectric properties of biological particles in suspension. For low volume fractions, are related to measured suspension by Maxwell's mixture equation. A number different techniques can be used measure spectrum frequency domain or time domain. In spectroscopy, data converted into using convolution Fourier transform, prior analysis. this paper, we present general method transforming equation from allowing analysis cell directly...

Measurements of the dielectric (or impedance) properties cells can be used as a general characterization and diagnostic tool.In this paper, we describe novel impedance spectroscopy technique for analysis single biological in suspension.The uses maximum length sequences (MLS) periodic excitation signal microfluidic cytometer.The method allows multi-frequency cell measurements to made short time period (ms).Spectral information is obtained frequency domain by applying fast M-sequence transform...

Analysis of the movement particles in a nonuniform field requires accurate knowledge electric distribution system. This paper describes method for analytically solving above interdigitated electrode arrays used dielectrophoresis (DEP) and traveling wave (twDEP), using Schwarz-Christoffel mapping method. The solutions are to calculate dielectrophoretic force both cases, electrorotational torque twDEP case. no approximations can take into account Neumann boundary condition represent an...