A5100363917- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Electrochemical Analysis and Applications
- Electrochemical sensors and biosensors
- Conducting polymers and applications
- Advanced Sensor and Energy Harvesting Materials
- SARS-CoV-2 and COVID-19 Research
- 3D Printing in Biomedical Research
- Analytical Chemistry and Sensors
- Cardiac Fibrosis and Remodeling
- Advanced Chemical Sensor Technologies
- Tissue Engineering and Regenerative Medicine
- Phagocytosis and Immune Regulation
- Ultrasound and Hyperthermia Applications
- Carbon and Quantum Dots Applications
- Extracellular vesicles in disease
- FOXO transcription factor regulation
- Advanced Biosensing Techniques and Applications
- Congenital heart defects research
- Viral Infections and Immunology Research
- Modernist Literature and Criticism
- SARS-CoV-2 detection and testing
- Advancements in Transdermal Drug Delivery
- Ultrasound in Clinical Applications
- Signaling Pathways in Disease
Second Affiliated Hospital of Zhejiang University
2023-2025
Zhongnan Hospital of Wuhan University
2024
Hubei University
2021-2024
Wuhan University
2024
Zhejiang University
2019-2023
National Clinical Research
2023
State Key Laboratory of Diagnosis and Treatment of Infectious Diseases
2023
National Center for Infectious Diseases
2023
Henan Provincial People's Hospital
2021
Zhengzhou University
2021
Abstract Skin‐interfaced electrochemical sensing devices are widely developed for biochemical at molecular levels. However, the electrodes fabricated with photolithography or printing technique hard to achieve high stretchability without special designs like serpentine shape. Also, most of them require wired connections external workstations data acquisition on‐board batteries power circuits, which largely restrain flexibility, simplification, and miniaturization devices. Here, a...
Paper-based lateral flow immunoassays (LFIAs) are cost-effective, portable, and simple methods for detection of diverse analytes, which however only provide qualitative or semiquantitative results lack sufficient sensitivity. A combination LFIA electrochemical detection, namely, immunoassay (eLFIA), enables quantitative analytes with high sensitivity, but the integration external electrodes makes system relatively expensive unstable. Herein, working, counter, reference were prepared directly...
Cortisol is commonly used as a significant biomarker of psychological or physical stress. With the accelerated pace life, non-invasive cortisol detection at point care (POC) in high demand for personal health monitoring. In this paper, an ultrasensitive immunosensor using gold nanoparticles/molybdenum disulfide/gold nanoparticles (AuNPs/MoS2/AuNPs) transducer was explored salivary monitoring POC with miniaturized differential pulse voltammetry (DPV) system based on smartphone. Covalent...
Manual lung ultrasound (LUS) scoring is influenced by clinicians' subjective interpretation, leading to potential inconsistencies and misdiagnoses due varying levels of experience. To improve monitoring pulmonary ventilation support early diagnosis, we propose an automated LUS network based on 8-point scale, named the detailed-global fusion residual (DGF-ResNet). This combines local global features using hybrid feature Block, which includes detail extraction (DFE) (GFE) Modules. The DFE...
Vibrio parahaemolyticus (VP) is a human pathogen widely distributed in marine environment. Eating raw or undercooked seafood contaminated with VP may cause acute gastroenteritis. Therefore, the requirement of rapid, sensitive...
Advancements in human-engineered heart tissue have enhanced the understanding of cardiac cellular alteration. Nevertheless, a human model simulating pathological remodeling following myocardial infarction for therapeutic development remains essential. Here we develop an engineered repair that replicates phased process, including hypoxic stress, fibrosis, and electrophysiological dysfunction. Transcriptomic analysis identifies nine critical signaling pathways related to fate transitions,...
Abstract As the cornerstone of tissue engineering and regeneration medicine research, developing a cost‐effective bionic extracellular matrix (ECM) that can precisely modulate cellular behavior form functional remains challenging. An artificial ECM combining polysaccharides fibrillar proteins to mimic structure composition natural provides promising solution for cardiac regeneration. In this study, we developed hydrogel scaffold by quaternized β ‐chitin derivative (QC) fibrin‐matrigel (FM)...
Cell size is a crucial physical property that significantly impacts cellular physiology and function. However, the influence of cell on stem specification remains largely unknown. Here, we investigated dynamic changes in during differentiation human pluripotent cells into definitive endoderm (DE). Interestingly, exhibited gradual decrease as DE progressed with higher stiffness. Furthermore, application hypertonic pressure or chemical to accelerate reduction specifically enhanced...
Exercise is one of the preferred management strategies for diabetic patients, but exercise mode including type, intensity, and duration time quite different each patient because individual differences. Inadequate has no effect on blood glucose control, while overexercise may cause serious side effects, such as hypoglycemia loss control. In this work, we report a closed-loop feedback in diabetes. A minimally invasive, biocompatible microneedle electrode patch was fabricated used continuously...
Diabetes is a chronic disease caused by decrease in insulin level or resistance. also has detrimental effects on the brain, which can lead to injury of blood-brain barrier and influence glucose transport. In this study, we use vivo electrochemical measurement explore variation brain early diabetic mice. The mice measured using carbon fiber microelectrode modified with osmium-derivatized polymer oxidase. electrode shows an excellent performance, antibiofouling ability, high stability, work...
Abstract An unprecedented number of COVID-19 vaccination campaign are under way worldwide. The spike protein SARS-CoV-2, which majorly binds to the host receptor angiotensin converting enzyme 2 (ACE2) for cell entry, is used by most vaccine as antigen. ACE2 highly expressed in heart and has been reported be protective multiple organs. Interaction with known reduce expression affect ACE2-mediated signal transduction. However, whether a spike-encoding will aggravate myocardial damage after...