A5037941962- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Advanced Sensor and Energy Harvesting Materials
- Electrochemical sensors and biosensors
- Neuroscience and Neural Engineering
- SARS-CoV-2 detection and testing
- Advanced Biosensing Techniques and Applications
- Conducting polymers and applications
- Covalent Organic Framework Applications
- Muscle activation and electromyography studies
- Luminescence and Fluorescent Materials
- CRISPR and Genetic Engineering
- 2D Materials and Applications
- Advanced Photocatalysis Techniques
- Molecular Sensors and Ion Detection
- Organic Electronics and Photovoltaics
- Parkinson's Disease Mechanisms and Treatments
- Advanced Memory and Neural Computing
- Energy Harvesting in Wireless Networks
- Neural dynamics and brain function
- Metal-Organic Frameworks: Synthesis and Applications
- Supercapacitor Materials and Fabrication
- Advanced Nanomaterials in Catalysis
- RNA Interference and Gene Delivery
- Electrochemical Analysis and Applications
Tongji University
2024-2025
Shanghai East Hospital
2024-2025
Fudan University
2021-2025
Zhejiang University
2016-2022
Fujian University of Traditional Chinese Medicine
2016-2020
Abstract Skin‐interfaced electrochemical sensing devices are widely developed for biochemical at molecular levels. However, the electrodes fabricated with photolithography or printing technique hard to achieve high stretchability without special designs like serpentine shape. Also, most of them require wired connections external workstations data acquisition on‐board batteries power circuits, which largely restrain flexibility, simplification, and miniaturization devices. Here, a...
The existing electrochemical biosensors lack controllable and intelligent merit to modulate the sensing process upon external stimulus, leading challenges in analyzing a few copies of biomarkers unamplified samples. Here, we present self-actuated molecular-electrochemical system that consists tentacle trunk modification on graphene microelectrode. contains probe an label keeps upright orientation, which increases recognition efficiency while decreasing pseudosignal. Once nucleic acids are...
Accurate and population-scale screening technology is crucial in the control prevention of COVID-19, such as pooled testing with high overall efficiency. Nevertheless, faces challenges sensitivity specificity due to diluted targets increased contaminations. Here, we develop a graphene field-effect transistor sensor modified triple-probe tetrahedral DNA framework (TDF) dimers for 10-in-1 SARS-CoV-2 RNA. The synergy effect triple probes well special nanostructure achieve higher binding...
In recent years, researchers have begun to develop smartphone-based electrochemical system support healthcare services. These systems are always combined with screen-printed electrodes perform early diagnosis, chronic disease monitoring, and health management. However, there still some challenges that will affect the practical application of electrodes, such as sensitivity, sensor performance, stability. this paper, a square wave voltammetry graphene was developed solve aforementioned...
Transition-metal dichalcogenides (TMDs) have been considered potential materials for the next generation of semiconductors. Realizing controllable growth TMD crystals is a prerequisite their future applications, which remains challenging. Here, we reveal new mechanism self-expanding molten salt-driven salt-assisted method and achieve patterned single-crystal arrays with size hundreds micrometers. Time-of-flight secondary ion mass spectroscopy other characterizations identify component salt...
Abstract For epidemic prevention and control, molecular diagnostic techniques such as field‐effect transistor (FET) biosensors is developed for rapid screening of infectious agents, including Mycobacterium tuberculosis , SARS‐CoV‐2, rhinovirus, others. They obtain results within a few minutes but exhibit diminished sensitivity (<75%) in unprocessed biological samples due to insufficient recognition low‐abundance analytes. Here, an electro‐enhanced strategy the precise detection...
Cardiovascular disease (CAD) is a major global public health issue, with mortality rates being significantly impacted by cold temperatures. Stable and reliable electrocardiogram (ECG) monitoring in environments crucial for early detection treatment of CAD. However, existing skin sensor struggle to balance freeze resistance, breathability, flexibility, conductivity adhesion at Here, we introduce solvent cross-linking strategy an situ transfer method prepare ultrathin bioionic gels, featuring...
Abstract Conventional nucleic acid detection methods often involve complex, time‐consuming amplification procedures and rely on sophisticated equipment, rendering them incapable of serving end customers or community hospitals. Here, a miniaturized automated point‐of‐care (POC) molecular diagnostic device is described that amplification‐free detects, via organic electrochemical transistors (OECTs) enhanced CRISPR/Cas12a system, achieving disease‐associated acids in real sample at attomolar...
Abstract Carbon aerogels with exceptional electrical properties are considered promising materials for bioelectronics in signal detection and stimulation. To address the mechanical incompatibilities of carbon bio‐interfaces, particularly dynamic tissues organs, incorporation hydrogels is an effective strategy. However, achieving excellent performance aerogel‐hydrogel hybrids remains a significant challenge. Two key factors contribute to this difficulty: 1) unrestricted hydrogel infiltration...
Abstract Cardiac pacemakers play a crucial role in arrhythmia treatment. Existing devices typically rely on rigid electrode components, leading to potential issues such as heart damage and detachment during prolonged cardiac motion due the mechanical mismatch with tissue. Additionally, traditional pacemakers, their batteries percutaneous leads, introduce infection risks limit freedom of movement. A wireless, battery‐free multifunctional bioelectronic device for pacing is developed. This...
To realize human-machine fusion, a hybrid neural pathway operating in the same modality with biological systems becomes imperative, which requires an interneuron unit to encode information biorecognizable spike sequences and tune frequency upon excitatory inhibitory neurotransmitters. Existing artificial interneurons cannot different neurotransmitters, activation threshold responsivity do not align those of counterparts, leading limited success constructing signal-harmonizing for...
In biological neural networks, chemical communication follows the reversible integrate-and-fire (I&F) dynamics model, enabling efficient, anti-interference signal transport. However, existing artificial neurons fail to follow I&F model in communication, causing irreversible potential accumulation and system dysfunction. Herein, we develop a supercapacitively gated neuron that mimics model. Upon upstream neurotransmitters, an electrochemical reaction occurs on graphene nanowall (GNW) gate...
As an important amino acid, cysteine is related to the development of various diseases. The quantitative detection great significance for both disease diagnosis and treatment. current labeling methods mainly rely on fluorescent probes, making it difficult in point-of-care testing (POCT). In this study, we proposed a label-free method quantification by novel photoelectrochemical (PEC) sensing using specific ion chelation probe. An indium tin oxide electrode loaded with nanoscale graphitic...