Qian Zhang

ORCID: 0000-0001-9924-6024
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About
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Research Areas
  • Advanced biosensing and bioanalysis techniques
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Biosensors and Analytical Detection
  • Electrochemical sensors and biosensors
  • Advancements in Transdermal Drug Delivery
  • Luminescence and Fluorescent Materials
  • Advanced Chemical Sensor Technologies
  • Advanced Nanomaterials in Catalysis
  • Liver physiology and pathology
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Advanced Drug Delivery Systems
  • Molecular Sensors and Ion Detection
  • MXene and MAX Phase Materials
  • Nanoplatforms for cancer theranostics
  • Olfactory and Sensory Function Studies
  • Liver Disease Diagnosis and Treatment
  • Crystallography and molecular interactions
  • Nanoparticle-Based Drug Delivery
  • Neurobiology and Insect Physiology Research
  • Nanocluster Synthesis and Applications
  • Gas Sensing Nanomaterials and Sensors
  • Carbon and Quantum Dots Applications
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Analytical Chemistry and Sensors

Zhejiang University
2014-2025

Guangzhou Medical University
2023-2025

Sichuan University
2013-2025

West China Hospital of Sichuan University
2023-2025

Bozhou People's Hospital
2025

Anhui Medical University
2022-2025

Qingdao University of Science and Technology
2008-2025

Chemical Synthesis Lab
2025

China West Normal University
2022-2025

Second Affiliated Hospital of Guangzhou Medical University
2023-2025

2D metal-organic frameworks (MOFs) are considered as promising electrochemical sensing materials and have attracted a lot of attention in recent years. Compared with bulk MOFs, the construction MOFs can increase exposure active sites by obtaining larger surface area ratio. Herein, facile one-pot hydrothermal synthesis pyridine-regulated lamellar Ni-MOFs ultrathin well-defined morphology is described. structure, Ni-MOF has higher site density, showing better glucose performance. The exhibits...

10.1002/advs.202304102 article EN cc-by Advanced Science 2023-07-20

Establishing how neurocircuit activation causes particular behaviors requires modulating the activity of specific neurons. Here, we demonstrate that magnetothermal genetic stimulation provides tetherless deep brain sufficient to evoke motor behavior in awake mice. The approach uses alternating magnetic fields heat superparamagnetic nanoparticles on neuronal membrane. Neurons, heat-sensitized by expressing TRPV1 are activated with field application. Magnetothermal cortex evoked ambulation,...

10.7554/elife.27069 article EN cc-by eLife 2017-08-15

A highly selective, sensitive, and low-cost hybrid sensing platform is developed based on extraordinary properties of explosives in an ionic liquid integrated electrochemical colorimetric approach.

10.1021/ja809104h article EN Journal of the American Chemical Society 2009-01-14

Semiconductor quantum dots (QDs) are highly attractive nanomaterials with wide biomedical applications owing to their unique photophysical properties. However, the adaptation of nonenzymatic QD nanosensor assembly sense low-abundance targets remains a great challenge. Herein, taking advantage dynamic DNA nanotechnology and single-molecule fluorescence detection, we demonstrate catalytic self-assembly QD-based microRNA directed by toehold-mediated strand displacement cascade for simple...

10.1021/acs.nanolett.9b02544 article EN Nano Letters 2019-08-28

Rationale:Recently, there is one-fifth of human deaths caused by cancer, leading to cancer treatment remains a hard nut crack in the medical field.Therefore, as an emerging diagnostic technology, mesoporous nanomaterials-based drug delivery systems integrated diagnosis and therapy have aroused tremendous interest owing visually targeting effect superior efficacy compared with traditional treatment.Methods: In this work, we successfully synthesized carbon-gold hybrid nanozyme nanoprobes,...

10.7150/thno.33266 article EN cc-by Theranostics 2019-01-01

On the basis of polarization-dependent absorption graphene under total internal reflection, we designed a graphene-based optical refractive index sensor with high resolution 1.7 × 10–8 and sensitivity 4.3 107 mV/RIU, as well an extensive dynamic range. This highly sensitive enables label-free, live-cell, accurate detection small quantity cancer cells among normal at single-cell level simultaneous distinction two cell lines without separation. It provides statistical distribution fewer cells....

10.1021/nl5012036 article EN Nano Letters 2014-05-05

How 2D Ti3 C2 enhances photocatalytic efficiency remains unclear. Now, it is shown that graphene quantum dots (GQDs) derived from , rather than itself, play the role of co-catalyst for La2 Ti2 O7 /Ti3 (LTC) composites during reaction. After modification derivatives, enhanced 16 times over pure . Solid-state NMR, Raman, and HRTEM results confirm existence GQDs in LTC composites. The are formed chemical change AlC2 to via HF etching, as Ti atoms removed unsaturated carbon bonds left, which...

10.1002/anie.201913095 article EN Angewandte Chemie International Edition 2019-11-11

Context Oxidative stress and inflammation are implicated in the aging process its related hepatic renal function decline. Chlorogenic acid (CGA) is one of most abundant polyphenol compounds human diet. Recently, CGA has shown vivo vitro antioxidant properties.Objective The current study investigates effects protective chlorogenic on d-galactose-induced liver kidney injury.Materials methods Hepatic injuries were induced a mouse model by subcutaneously injection d-galactose (d-gal; 100 mg/kg)...

10.3109/13880209.2015.1093510 article EN Pharmaceutical Biology 2016-01-25

Abstract We propose a hybrid circuit for spoof surface plasmon polaritons (SPPs) and spatial waveguide modes to develop new microwave devices. The includes SPP made of two anti-symmetric corrugated metallic strips traditional substrate integrated (SIW). From dispersion relations, we show that the electromagnetic waves only can propagate through when operating frequency is less than cut-off greater SIW, generating efficient band-pass filters. demonstrate pass band controllable in large range...

10.1038/srep16531 article EN cc-by Scientific Reports 2015-11-10

Abstract Purpose: Despite the importance of MET oncogene in many malignancies, clinical strategies targeting c-Met have benefitted only small subsets patients with tumors driven by signaling through pathway, thereby necessitating selection amplification and/or activation most likely to respond. An ADC could overcome these limitations potential as a broad-acting therapeutic. Experimental Design: ABBV-399 was generated c-Met–targeting antibody, ABT-700. Antitumor activity evaluated cancer...

10.1158/1078-0432.ccr-16-1568 article EN Clinical Cancer Research 2016-08-30
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